asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
External Links
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 121 - 130 of 222 in total
Gene ID Gene Symbol Description Source
5621 PRNP prion protein (Kanno blood group)
5660 PSAP prosaposin
5728 PTEN phosphatase and tensin homolog
5730 PTGDS prostaglandin D2 synthase
5742 PTGS1 prostaglandin-endoperoxide synthase 1
5743 PTGS2 prostaglandin-endoperoxide synthase 2
6319 SCD stearoyl-CoA desaturase
6385 SDC4 syndecan 4
6392 SDHD succinate dehydrogenase complex subunit D
6401 SELE selectin E
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
12654 Chi3l1 chitinase 3 like 1
12655 Chil3 chitinase-like 3
16182 Il18r1 interleukin 18 receptor 1
16846 Lep leptin
17082 Il1rl1 interleukin 1 receptor-like 1
18654 Pgf placental growth factor
18783 Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent)
21897 Tlr1 toll-like receptor 1
21898 Tlr4 toll-like receptor 4
21899 Tlr6 toll-like receptor 6
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source
24835 Tnf tumor necrosis factor
25556 Il1rl1 interleukin 1 receptor-like 1
25591 Parp1 poly (ADP-ribose) polymerase 1
25608 Lep leptin
29260 Tlr4 toll-like receptor 4
65270 Abo3 histo-blood group ABO system transferase 3
89824 Chi3l1 chitinase 3 like 1
94203 Pgf placental growth factor
113901 Chia chitinase, acidic
296504 Abo2 histo-blood group ABO system transferase 2
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
38223 Cht2 Chitinase 2
38973 se sepia
43222 Tl Toll
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
560788 parp1 poly (ADP-ribose) polymerase 1
563897 gbgt1l5 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5
566487 gbgt1l2 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2
100005565 gbgt1l8 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8
100005704 gbgt1l9 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 9
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo.1 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100497509 abo.4 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 Xenopus tropicalis (tropical clawed frog)
108698211 abo.2.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog Xenopus laevis (African clawed frog)
108698863 abo.4.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog Xenopus laevis (African clawed frog)
Displaying all 3 entries
Gene ID Gene Symbol Description Source
180628 cht-1 putative endochitinase
183000 gsto-1 Glutathione transferase omega-1
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
850666 GTT2 glutathione transferase GTT2
851977 CTS2 putative chitinase
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
HP:0000006 Autosomal dominant inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024