glioblastoma

Summary
Synonym
  • GBM
  • adult glioblastoma multiforme
  • glioblastoma multiforme
  • grade IV adult Astrocytic tumor
  • primary glioblastoma multiforme
  • spongioblastoma multiforme
Definition
A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Super Class
malignant astrocytoma
Disease Ontology
DOID:3068
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 54 in total
Gene ID Gene Symbol Description Source
546 ATRX ATRX chromatin remodeler
575 ADGRB1 adhesion G protein-coupled receptor B1
710 SERPING1 serpin family G member 1
1116 CHI3L1 chitinase 3 like 1
1363 CPE carboxypeptidase E
1508 CTSB cathepsin B
1512 CTSH cathepsin H
1755 DMBT1 deleted in malignant brain tumors 1
1869 E2F1 E2F transcription factor 1
1950 EGF epidermal growth factor
Displaying entries 11 - 20 of 38 in total
Gene ID Gene Symbol Description Source
15926 Idh1 isocitrate dehydrogenase 1 (NADP+), soluble
16170 Il16 interleukin 16
16542 Kdr kinase insert domain protein receptor
16653 Kras Kirsten rat sarcoma viral oncogene homolog
16728 L1cam L1 cell adhesion molecule
17390 Mmp2 matrix metallopeptidase 2
17395 Mmp9 matrix metallopeptidase 9
18591 Pdgfb platelet derived growth factor, B polypeptide
18596 Pdgfrb platelet derived growth factor receptor, beta polypeptide
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
Displaying entries 1 - 10 of 24 in total
Gene ID Gene Symbol Description Source
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24628 Pdgfb platelet derived growth factor subunit B
24629 Pdgfrb platelet derived growth factor receptor beta
24842 Tp53 tumor protein p53
25313 Egf epidermal growth factor
25425 Ctsh cathepsin H
25589 Kdr kinase insert domain receptor
25669 Cpe carboxypeptidase E
29414 Akt3 AKT serine/threonine kinase 3
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
Displaying entries 11 - 13 of 13 in total
Gene ID Gene Symbol Description Source
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
42850 Atg6 Autophagy-related 6
Displaying 1 entry
Gene ID Gene Symbol Description Source
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source
180628 cht-1 putative endochitinase
180931 cpr-6 Cathepsin B-like cysteine proteinase 6
181684 cpd-2 Peptidase M14 carboxypeptidase A domain-containing protein
186632 ver-4 Tyrosine-protein kinase receptor ver-4
Displaying all 7 entries
Gene ID Gene Symbol Description Source
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
853313 PBS2 mitogen-activated protein kinase kinase PBS2
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3
856699 NPP2 nucleotide diphosphatase/phosphodiesterase NPP2

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Last updated: December 9, 2024