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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glioblastoma
Summary
- Synonym
-
- GBM
- adult glioblastoma multiforme
- glioblastoma multiforme
- grade IV adult Astrocytic tumor
- primary glioblastoma multiforme
- spongioblastoma multiforme
- Definition
- A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
- Super Class
- malignant astrocytoma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 546 | ATRX | ATRX chromatin remodeler | |
| 575 | ADGRB1 | adhesion G protein-coupled receptor B1 | |
| 710 | SERPING1 | serpin family G member 1 | |
| 1116 | CHI3L1 | chitinase 3 like 1 | |
| 1363 | CPE | carboxypeptidase E | |
| 1508 | CTSB | cathepsin B | |
| 1512 | CTSH | cathepsin H | |
| 1755 | DMBT1 | deleted in malignant brain tumors 1 | |
| 1869 | E2F1 | E2F transcription factor 1 | |
| 1950 | EGF | epidermal growth factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 18654 | Pgf | placental growth factor | |
| 19224 | Ptgs1 | prostaglandin-endoperoxide synthase 1 | |
| 19225 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 19263 | Ptprb | protein tyrosine phosphatase receptor type B | |
| 20539 | Slc7a5 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | |
| 20848 | Stat3 | signal transducer and activator of transcription 3 | |
| 20850 | Stat5a | signal transducer and activator of transcription 5A | |
| 21923 | Tnc | tenascin C | |
| 22059 | Trp53 | transformation related protein 53 | |
| 22589 | Atrx | ATRX, chromatin remodeler |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24479 | Idh1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 24628 | Pdgfb | platelet derived growth factor subunit B | |
| 24629 | Pdgfrb | platelet derived growth factor receptor beta | |
| 24842 | Tp53 | tumor protein p53 | |
| 25313 | Egf | epidermal growth factor | |
| 25425 | Ctsh | cathepsin H | |
| 25589 | Kdr | kinase insert domain receptor | |
| 25669 | Cpe | carboxypeptidase E | |
| 29414 | Akt3 | AKT serine/threonine kinase 3 | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850391 | NPP1 | nucleotide diphosphatase/phosphodiesterase NPP1 | |
| 850871 | IDP2 | isocitrate dehydrogenase (NADP(+)) IDP2 | |
| 851493 | IDP1 | isocitrate dehydrogenase (NADP(+)) IDP1 | |
| 851977 | CTS2 | putative chitinase | |
| 853313 | PBS2 | mitogen-activated protein kinase kinase PBS2 | |
| 855723 | IDP3 | isocitrate dehydrogenase (NADP(+)) IDP3 | |
| 856699 | NPP2 | nucleotide diphosphatase/phosphodiesterase NPP2 |
