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Standards Ontologies Notations
glioblastoma

Summary
Synonym
  • GBM
  • adult glioblastoma multiforme
  • glioblastoma multiforme
  • grade IV adult Astrocytic tumor
  • primary glioblastoma multiforme
  • spongioblastoma multiforme
Definition
A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Super Class
malignant astrocytoma
Disease Ontology
DOID:3068
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 31 - 40 of 54 in total
Gene ID Gene Symbol Description Source
5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5426 POLE DNA polymerase epsilon, catalytic subunit
5605 MAP2K2 mitogen-activated protein kinase kinase 2
5606 MAP2K3 mitogen-activated protein kinase kinase 3
5742 PTGS1 prostaglandin-endoperoxide synthase 1
5743 PTGS2 prostaglandin-endoperoxide synthase 2
5787 PTPRB protein tyrosine phosphatase receptor type B
5925 RB1 RB transcriptional corepressor 1
6165 RPL35A ribosomal protein L35a
6774 STAT3 signal transducer and activator of transcription 3
Displaying entries 31 - 38 of 38 in total
Gene ID Gene Symbol Description Source
23797 Akt3 thymoma viral proto-oncogene 3
26397 Map2k3 mitogen-activated protein kinase kinase 3
29810 Bag3 BCL2-associated athanogene 3
57808 Rpl35a ribosomal protein L35A
74769 Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
107831 Adgrb1 adhesion G protein-coupled receptor B1
170757 Adgrl4 adhesion G protein-coupled receptor L4
268345 Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2
Displaying entries 1 - 10 of 24 in total
Gene ID Gene Symbol Description Source
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24628 Pdgfb platelet derived growth factor subunit B
24629 Pdgfrb platelet derived growth factor receptor beta
24842 Tp53 tumor protein p53
25313 Egf epidermal growth factor
25425 Ctsh cathepsin H
25589 Kdr kinase insert domain receptor
25669 Cpe carboxypeptidase E
29414 Akt3 AKT serine/threonine kinase 3
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
Displaying entries 11 - 13 of 13 in total
Gene ID Gene Symbol Description Source
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
42850 Atg6 Autophagy-related 6
Displaying 1 entry
Gene ID Gene Symbol Description Source
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source
174437 dep-1 Receptor-type tyrosine-protein phosphatase dep-1
175182 ver-1 Protein ver-1
177078 lad-2 Ig-like domain-containing protein;Neuroglian
177940 egl-21 Carboxypeptidase E
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
179663 enpp-1 Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;NUC domain-containing protein
179665 C27A7.3 Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.3
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180033 cpr-3 Cathepsin B-like cysteine proteinase 3
180351 W01F3.2 Uncharacterized protein
Displaying all 7 entries
Gene ID Gene Symbol Description Source
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
853313 PBS2 mitogen-activated protein kinase kinase PBS2
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3
856699 NPP2 nucleotide diphosphatase/phosphodiesterase NPP2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024