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Standards Ontologies Notations
pulmonary fibrosis

Summary
Synonym
  • Fibrosis of lung
Definition
An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
Super Class
interstitial lung disease
Disease Ontology
DOID:3770
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 69 in total
Gene ID Gene Symbol Description Source
999 CDH1 cadherin 1
1116 CHI3L1 chitinase 3 like 1
1131 CHRM3 cholinergic receptor muscarinic 3
1233 CCR4 C-C motif chemokine receptor 4
1234 CCR5 C-C motif chemokine receptor 5
1277 COL1A1 collagen type I alpha 1 chain
1278 COL1A2 collagen type I alpha 2 chain
1437 CSF2 colony stimulating factor 2
1490 CCN2 cellular communication network factor 2
1636 ACE angiotensin I converting enzyme
Displaying entries 51 - 56 of 56 in total
Gene ID Gene Symbol Description Source
50701 Elane elastase, neutrophil expressed
58861 Cysltr1 cysteinyl leukotriene receptor 1
74006 Dnm1l dynamin 1-like
76898 B3gat1 beta-1,3-glucuronyltransferase 1
81897 Tlr9 toll-like receptor 9
83995 Mmp1a matrix metallopeptidase 1a (interstitial collagenase)
Displaying entries 31 - 40 of 42 in total
Gene ID Gene Symbol Description Source
89824 Chi3l1 chitinase 3 like 1
114099 Cysltr1 cysteinyl leukotriene receptor 1
114114 Dnm1l dynamin 1-like
116510 Timp1 TIMP metallopeptidase inhibitor 1
116553 Il13 interleukin 13
116630 Csf2 colony stimulating factor 2
117029 Ccr5 C-C motif chemokine receptor 5
117108 B3gat1 beta-1,3-glucuronyltransferase 1
192155 Sftpb surfactant protein B
287287 Il4 interleukin 4
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
31293 N Notch
31926 Idgf4 Imaginal disc growth factor 4
34189 Acer Angiotensin-converting enzyme-related
34282 GlcAT-S Glucuronyltransferase S
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30718 notch1a notch receptor 1a
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
140421 jag1a jagged canonical Notch ligand 1a
386856 pdgfra platelet-derived growth factor receptor, alpha polypeptide
548607 b3gat1a beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100332644 b3gat1b beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
100037907 b3gat1 beta-1,3-glucuronyltransferase 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174517 sqv-8 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175781 daf-4 Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase
176286 glp-1 glp-1/Notch intracellular domain
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178672 srp-3 Serpin domain-containing protein
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179962 gar-3 Muscarinic acetylcholine receptor gar-3
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851977 CTS2 putative chitinase
853177 APL6 Apl6p
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024