acquired immunodeficiency syndrome

Summary
Synonym
  • AIDS
  • acquired Immune deficiency
Definition
A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.
Super Class
human immunodeficiency virus infectious disease
Disease Ontology
DOID:635
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
684 BST2 bone marrow stromal cell antigen 2
920 CD4 CD4 molecule
925 CD8A CD8 subunit alpha
968 CD68 CD68 molecule
3105 HLA-A major histocompatibility complex, class I, A
3481 IGF2 insulin like growth factor 2
3802 KIR2DL1 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
3813 KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
5243 ABCB1 ATP binding cassette subfamily B member 1
7124 TNF tumor necrosis factor
Displaying entries 11 - 20 of 24 in total
Gene ID Gene Symbol Description Source
16002 Igf2 insulin-like growth factor 2
17086 Ncr1 natural cytotoxicity triggering receptor 1
18669 Abcb1b ATP-binding cassette, sub-family B member 1B
18671 Abcb1a ATP-binding cassette, sub-family B member 1A
21926 Tnf tumor necrosis factor
21937 Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a
21938 Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b
69165 Cd209b CD209b antigen
69550 Bst2 bone marrow stromal cell antigen 2
110557 H2-Q6 histocompatibility 2, Q region locus 6
Displaying all 9 entries
Gene ID Gene Symbol Description Source
24483 Igf2 insulin-like growth factor 2
24835 Tnf tumor necrosis factor
24930 Cd8a CD8 subunit alpha
24932 Cd4 Cd4 molecule
25625 Tnfrsf1a TNF receptor superfamily member 1A
117547 Ncr1 natural cytotoxicity triggering receptor 1
156767 Tnfrsf1b TNF receptor superfamily member 1B
353253 Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
378947 Bst2 bone marrow stromal cell antigen 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 2 entries
Gene ID Gene Symbol Description Source
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6

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Last updated: December 9, 2024