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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
lung disease
Summary
- Definition
- A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
- Super Class
- lower respiratory tract disease
External Links
- Disease Ontology
- DOID:850
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4353 | MPO | myeloperoxidase | |
| 4582 | MUC1 | mucin 1, cell surface associated | |
| 4843 | NOS2 | nitric oxide synthase 2 | |
| 4846 | NOS3 | nitric oxide synthase 3 | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 6347 | CCL2 | C-C motif chemokine ligand 2 | |
| 6352 | CCL5 | C-C motif chemokine ligand 5 | |
| 6376 | CX3CL1 | C-X3-C motif chemokine ligand 1 | |
| 6439 | SFTPB | surfactant protein B | |
| 6440 | SFTPC | surfactant protein C |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 13649 | Egfr | epidermal growth factor receptor | |
| 13653 | Egr1 | early growth response 1 | |
| 14063 | F2rl1 | F2R like trypsin receptor 1 | |
| 14815 | Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | |
| 15978 | Ifng | interferon gamma | |
| 16153 | Il10 | interleukin 10 | |
| 16163 | Il13 | interleukin 13 | |
| 16168 | Il15 | interleukin 15 | |
| 16175 | Il1a | interleukin 1 alpha | |
| 16182 | Il18r1 | interleukin 18 receptor 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 84007 | C3ar1 | complement C3a receptor 1 | |
| 89808 | Cx3cl1 | C-X3-C motif chemokine ligand 1 | |
| 113959 | C5ar1 | complement C5a receptor 1 | |
| 116553 | Il13 | interleukin 13 | |
| 116562 | Il2 | interleukin 2 | |
| 116677 | F2rl1 | F2R like trypsin receptor 1 | |
| 192155 | Sftpb | surfactant protein B | |
| 302668 | Ace2 | angiotensin converting enzyme 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 173828 | rig-6 | Contactin rig-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180841 | gnrr-4 | G-protein coupled receptors family 1 profile domain-containing protein | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 181288 | pxn-2 | Peroxidasin homolog pxn-2 |
