cholesteatoma

Summary
Definition
A keratosis that is characterized by keratinizing squamous epithelium located in middle ear and/or mastoid, subepithelial connective tissue and by the progressive accumulation of keratin debris with or without surrounding inflammatory reaction.
Super Class
keratosis
Disease Ontology
DOID:869
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying all 9 entries
Gene ID Gene Symbol Description Source
2069 EREG epiregulin
3082 HGF hepatocyte growth factor
3552 IL1A interleukin 1 alpha
4313 MMP2 matrix metallopeptidase 2
4318 MMP9 matrix metallopeptidase 9
6775 STAT4 signal transducer and activator of transcription 4
7097 TLR2 toll like receptor 2
7099 TLR4 toll like receptor 4
7422 VEGFA vascular endothelial growth factor A
Displaying all 8 entries
Gene ID Gene Symbol Description Source
13874 Ereg epiregulin
15234 Hgf hepatocyte growth factor
16175 Il1a interleukin 1 alpha
17390 Mmp2 matrix metallopeptidase 2
17395 Mmp9 matrix metallopeptidase 9
21898 Tlr4 toll-like receptor 4
22339 Vegfa vascular endothelial growth factor A
24088 Tlr2 toll-like receptor 2
Displaying all 7 entries
Gene ID Gene Symbol Description Source
24446 Hgf hepatocyte growth factor
24493 Il1a interleukin 1 alpha
29260 Tlr4 toll-like receptor 4
59325 Ereg epiregulin
81686 Mmp2 matrix metallopeptidase 2
81687 Mmp9 matrix metallopeptidase 9
83785 Vegfa vascular endothelial growth factor A
Displaying 1 entry
Gene ID Gene Symbol Description Source
43222 Tl Toll
Displaying 1 entry
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
Displaying all 2 entries
Gene ID Gene Symbol Description Source
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024