pemphigus

Summary
Definition
An autoimmune disease of skin and connective tissue that is characterized by blistering of the outer layer of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals), causing lesions and blisters that are easily ruptured.
Super Class
autoimmune disease of skin and connective tissue bullous skin disease
Disease Ontology
DOID:9182
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying all 7 entries
Gene ID Gene Symbol Description Source
831 CAST calpastatin
948 CD36 CD36 molecule (CD36 blood group)
958 CD40 CD40 molecule
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3558 IL2 interleukin 2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025