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MIRAGE
Interleukin-2

Summary
UniProt ID
P60568
Gene Symbol
  • IL2
Gene ID
3558
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P60568
PubChem
P60568
Re-Glyco
P60568
Annotation
Keyword
  • 3D-structure
  • Adaptive immunity
  • Chromosomal rearrangement
  • Cytokine
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Growth factor
  • Pharmaceutical
  • Proto-oncogene
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 2 entries
GO Term
extracellular region
extracellular space
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
23 O-linked (GalNAc...) threonine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Interleukin receptor SHC signaling Homo sapiens
Interleukin-2 signaling Homo sapiens
RAF/MAP kinase cascade Homo sapiens
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Homo sapiens
Disease
Displaying entries 1 - 10 of 32 in total
DO ID Disease Name Source
DOID:0050866 oral squamous cell carcinoma
DOID:0060500 drug allergy
DOID:0081120 Graves ophthalmopathy
DOID:0081267 graft-versus-host disease
DOID:10003 sensorineural hearing loss
DOID:10652 Alzheimer's disease
DOID:10964 cholesteatoma of middle ear
DOID:11054 urinary bladder cancer
DOID:12361 Graves' disease
DOID:12704 ataxia telangiectasia
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025