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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 325 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
111 ADCY5 adenylate cyclase 5
133 ADM adrenomedullin
142 PARP1 poly(ADP-ribose) polymerase 1
150 ADRA2A adrenoceptor alpha 2A
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
183 AGT angiotensinogen
186 AGTR2 angiotensin II receptor type 2
Displaying entries 1 - 10 of 249 in total
Gene ID Gene Symbol Description Source
11303 Abca1 ATP-binding cassette, sub-family A member 1
11421 Ace angiotensin I converting enzyme
11450 Adipoq adiponectin, C1Q and collagen domain containing
11491 Adam17 a disintegrin and metallopeptidase domain 17
11551 Adra2a adrenergic receptor, alpha 2a
11556 Adrb3 adrenergic receptor, beta 3
11596 Ager advanced glycosylation end product-specific receptor
11601 Angpt2 angiopoietin 2
11609 Agtr2 angiotensin II receptor, type 2
11625 Ahsg alpha-2-HS-glycoprotein
Displaying entries 41 - 50 of 166 in total
Gene ID Gene Symbol Description Source
24890 Esr1 estrogen receptor 1
24946 F9 coagulation factor IX
24953 Gcgr glucagon receptor
25008 Lta lymphotoxin alpha
25024 Gipr gastric inhibitory polypeptide receptor
25059 Hk2 hexokinase 2
25062 Gpd2 glycerol-3-phosphate dehydrogenase 2
25083 Adra2a adrenoceptor alpha 2A
25116 Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1
25121 Pcsk2 proprotein convertase subtilisin/kexin type 2
Displaying entries 71 - 80 of 80 in total
Gene ID Gene Symbol Description Source
53511 Ugt37D1 UDP-glycosyltransferase family 37 member D1
53512 Ugt37E1 UDP-glycosyltransferase family 37 member E1
53513 Ugt37C2 UDP-glycosyltransferase family 37 member C2
53583 Ugt37C1 UDP-glycosyltransferase family 37 member C1
53584 Ugt37B1 UDP-glycosyltransferase family 37 member B1
117364 Hex-t1 Hexokinase testis 1
140439 Tre1 Trapped in endoderm 1
246614 Ugt50B3 UDP-glycosyltransferase family 50 member B3
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
3772574 Fuca alpha-L-fucosidase
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source Organism
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380341 pon2.L paraoxonase 2 L homeolog Xenopus laevis (African clawed frog)
394283 sdc2.S syndecan 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
Displaying entries 21 - 30 of 69 in total
Gene ID Gene Symbol Description Source
177372 cpi-1 Cystatin cpi-1
177557 klo-1 Glycoside hydrolase family 1 protein
177668 C49C8.5 Fibrinogen C-terminal domain-containing protein
177850 gon-1 A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein
177911 Y43C5A.2 Fibrinogen C-terminal domain-containing protein
177940 egl-21 Carboxypeptidase E
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178215 pgp-1 Multidrug resistance protein pgp-1
178330 ugt-22 UDP-glucuronosyltransferase
178585 srp-1 Serpin domain-containing protein
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2645 GCK glucokinase
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024