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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steatotic liver disease
Summary
- Synonym
-
- Fatty change of liver
- SLD
- Steatosis of liver
- alcoholic fatty liver
- fatty liver disease
- hepatic lipidosis
- hepatic steatosis
- Definition
- A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
- Super Class
- lipid storage disease liver disease
External Links
- Disease Ontology
- DOID:9452
- Mondo Disease Ontology
- MeSH
- UMLS
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 10998 | SLC27A5 | solute carrier family 27 member 5 | |
| 11181 | TREH | trehalase | |
| 11343 | MGLL | monoglyceride lipase | |
| 22933 | SIRT2 | sirtuin 2 | |
| 23098 | SARM1 | sterile alpha and TIR motif containing 1 | |
| 23171 | GPD1L | glycerol-3-phosphate dehydrogenase 1 like | |
| 23175 | LPIN1 | lipin 1 | |
| 23213 | SULF1 | sulfatase 1 | |
| 23409 | SIRT4 | sirtuin 4 | |
| 23417 | MLYCD | malonyl-CoA decarboxylase |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 14377 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 | |
| 15558 | Htr2a | 5-hydroxytryptamine (serotonin) receptor 2A | |
| 16333 | Ins1 | insulin I | |
| 16334 | Ins2 | insulin II | |
| 16846 | Lep | leptin | |
| 19013 | Ppara | peroxisome proliferator activated receptor alpha | |
| 19017 | Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | |
| 22228 | Ucp2 | uncoupling protein 2 (mitochondrial, proton carrier) | |
| 67800 | Dgat2 | diacylglycerol O-acyltransferase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24385 | Gck | glucokinase | |
| 24505 | Ins1 | insulin 1 | |
| 24506 | Ins2 | insulin 2 | |
| 25608 | Lep | leptin | |
| 25634 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 | |
| 25747 | Ppara | peroxisome proliferator activated receptor alpha | |
| 29595 | Htr2a | 5-hydroxytryptamine receptor 2A | |
| 54315 | Ucp2 | uncoupling protein 2 | |
| 83516 | Ppargc1a | PPARG coactivator 1 alpha | |
| 252900 | Dgat2 | diacylglycerol O-acyltransferase 2 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 395003 | dgat2 | diacylglycerol O-acyltransferase 2 | Xenopus tropicalis (tropical clawed frog) |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P14151 | L-selectin | |
| P14207 | Folate receptor beta | |
| P14550 | Aldo-keto reductase family 1 member A1 | |
| P14618 | Pyruvate kinase PKM | |
| P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | |
| P15104 | Glutamine synthetase | |
| P15121 | Aldo-keto reductase family 1 member B1 | |
| P15813 | Antigen-presenting glycoprotein CD1d | |
| P15907 | Beta-galactoside alpha-2,6-sialyltransferase 1 | |
| P16070 | CD44 antigen |
