steatotic liver disease

Summary
Synonym
  • Fatty change of liver
  • SLD
  • Steatosis of liver
  • alcoholic fatty liver
  • fatty liver disease
  • hepatic lipidosis
  • hepatic steatosis
Definition
A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
Super Class
lipid storage disease liver disease
External Links
Disease Ontology
DOID:9452
Mondo Disease Ontology
MeSH
UMLS
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 21 - 30 of 234 in total
Gene ID Gene Symbol Description Source
249 ALPL alkaline phosphatase, biomineralization associated
250 ALPP alkaline phosphatase, placental
353 APRT adenine phosphoribosyltransferase
412 STS steroid sulfatase
419 ART3 ADP-ribosyltransferase 3 (inactive)
537 ATP6AP1 ATPase H+ transporting accessory protein 1
570 BAAT bile acid-CoA:amino acid N-acyltransferase
847 CAT catalase
873 CBR1 carbonyl reductase 1
912 CD1D CD1d molecule
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
14377 G6pc1 glucose-6-phosphatase catalytic subunit 1
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
16333 Ins1 insulin I
16334 Ins2 insulin II
16846 Lep leptin
19013 Ppara peroxisome proliferator activated receptor alpha
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
22228 Ucp2 uncoupling protein 2 (mitochondrial, proton carrier)
67800 Dgat2 diacylglycerol O-acyltransferase 2
Displaying all 10 entries
Gene ID Gene Symbol Description Source
24385 Gck glucokinase
24505 Ins1 insulin 1
24506 Ins2 insulin 2
25608 Lep leptin
25634 G6pc1 glucose-6-phosphatase catalytic subunit 1
25747 Ppara peroxisome proliferator activated receptor alpha
29595 Htr2a 5-hydroxytryptamine receptor 2A
54315 Ucp2 uncoupling protein 2
83516 Ppargc1a PPARG coactivator 1 alpha
252900 Dgat2 diacylglycerol O-acyltransferase 2
Displaying all 3 entries
Gene ID Gene Symbol Description Source
37028 ACOX1 acyl-CoA oxidase 1
43191 Hex-t2 Hexokinase testis 2
117364 Hex-t1 Hexokinase testis 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
565316 dgat2 diacylglycerol O-acyltransferase 2
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
395003 dgat2 diacylglycerol O-acyltransferase 2 Xenopus tropicalis (tropical clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
853418 KAR2 Hsp70 family ATPase KAR2
854419 DGA1 diacylglycerol O-acyltransferase

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024