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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 133 in total
Gene ID Gene Symbol Description Source
43 ACHE acetylcholinesterase (Yt blood group)
153 ADRB1 adrenoceptor beta 1
177 AGER advanced glycosylation end-product specific receptor
217 ALDH2 aldehyde dehydrogenase 2 family member
335 APOA1 apolipoprotein A1
336 APOA2 apolipoprotein A2
338 APOB apolipoprotein B
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
355 FAS Fas cell surface death receptor
Displaying entries 1 - 10 of 102 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11423 Ache acetylcholinesterase
11450 Adipoq adiponectin, C1Q and collagen domain containing
11554 Adrb1 adrenergic receptor, beta 1
11596 Ager advanced glycosylation end product-specific receptor
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
11754 Aoc3 amine oxidase, copper containing 3
11814 Apoc3 apolipoprotein C-III
11998 Avp arginine vasopressin
12038 Bche butyrylcholinesterase
Displaying entries 41 - 50 of 61 in total
Gene ID Gene Symbol Description Source
29539 Aldh2 aldehyde dehydrogenase 2 family member
29702 Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3
29714 Ptprn2 protein tyrosine phosphatase, receptor type N2
54225 Apob apolipoprotein B
59086 Tgfb1 transforming growth factor, beta 1
60350 Cd14 CD14 molecule
60582 Il1rn interleukin 1 receptor antagonist
64133 Xylt1 xylosyltransferase 1
83817 Ache acetylcholinesterase
84024 Pon1 paraoxonase 1
Displaying entries 11 - 20 of 43 in total
Gene ID Gene Symbol Description Source
35137 Ugt36F1 UDP-glycosyltransferase family 36 member F1
35138 Ugt36D1 UDP-glycosyltransferase family 36 member D1
35139 Ugt36E1 UDP-glycosyltransferase family 36 member E1
36232 Sod3 Superoxide dismutase 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
37420 Ugt49B1 UDP-glycosyltransferase family 49 member B1
37455 Egfr Epidermal growth factor receptor
38288 oxt peptide O-xylosyltransferase
39435 Tsf2 Transferrin 2
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 11 - 20 of 29 in total
Gene ID Gene Symbol Description Source
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178330 ugt-22 UDP-glucuronosyltransferase
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179199 timp-1 NTR domain-containing protein
180418 ncam-1 NCAM (neural cell adhesion molecule) homolog
180628 cht-1 putative endochitinase
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
180836 W01C8.5 DM13 domain-containing protein
180837 cat-1 Major facilitator superfamily (MFS) profile domain-containing protein
180939 smf-1 NRAMP-like transporter smf-1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024