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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 1 - 10 of 133 in total
Gene ID Gene Symbol Description Source
43 ACHE acetylcholinesterase (Yt blood group)
153 ADRB1 adrenoceptor beta 1
177 AGER advanced glycosylation end-product specific receptor
217 ALDH2 aldehyde dehydrogenase 2 family member
335 APOA1 apolipoprotein A1
336 APOA2 apolipoprotein A2
338 APOB apolipoprotein B
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
355 FAS Fas cell surface death receptor
Displaying entries 1 - 10 of 102 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11423 Ache acetylcholinesterase
11450 Adipoq adiponectin, C1Q and collagen domain containing
11554 Adrb1 adrenergic receptor, beta 1
11596 Ager advanced glycosylation end product-specific receptor
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
11754 Aoc3 amine oxidase, copper containing 3
11814 Apoc3 apolipoprotein C-III
11998 Avp arginine vasopressin
12038 Bche butyrylcholinesterase
Displaying entries 21 - 30 of 61 in total
Gene ID Gene Symbol Description Source
25008 Lta lymphotoxin alpha
25235 Ghr growth hormone receptor
25325 Il10 interleukin 10
25361 Vcam1 vascular cell adhesion molecule 1
25385 Faslg Fas ligand
25419 Crp C-reactive protein
25464 Icam1 intercellular adhesion molecule 1
25544 Sele selectin E
25549 Slc18a2 solute carrier family 18 member A2
25660 Cd28 Cd28 molecule
Displaying entries 41 - 43 of 43 in total
Gene ID Gene Symbol Description Source
53583 Ugt37C1 UDP-glycosyltransferase family 37 member C1
53584 Ugt37B1 UDP-glycosyltransferase family 37 member B1
3772574 Fuca alpha-L-fucosidase
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 11 - 20 of 29 in total
Gene ID Gene Symbol Description Source
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178330 ugt-22 UDP-glucuronosyltransferase
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179199 timp-1 NTR domain-containing protein
180418 ncam-1 NCAM (neural cell adhesion molecule) homolog
180628 cht-1 putative endochitinase
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
180836 W01C8.5 DM13 domain-containing protein
180837 cat-1 Major facilitator superfamily (MFS) profile domain-containing protein
180939 smf-1 NRAMP-like transporter smf-1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024