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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
External Links
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 101 - 110 of 176 in total
Gene ID Gene Symbol Description Source
5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
5563 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2
5589 PRKCSH PRKCSH beta subunit of glucosidase II
5728 PTEN phosphatase and tensin homolog
5743 PTGS2 prostaglandin-endoperoxide synthase 2
5968 REG1B regenerating family member 1 beta
5973 RENBP renin binding protein
6319 SCD stearoyl-CoA desaturase
6383 SDC2 syndecan 2
6401 SELE selectin E
Displaying entries 11 - 17 of 17 in total
Gene ID Gene Symbol Description Source
18609 Pdx1 pancreatic and duodenal homeobox 1
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
24088 Tlr2 toll-like receptor 2
71665 Fuca1 fucosidase, alpha-L- 1, tissue
233781 Xylt1 xylosyltransferase 1
394436 Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24835 Tnf tumor necrosis factor
24861 Ugt1a1 UDP glucuronosyltransferase family 1 member A1
24925 Adrb1 adrenoceptor beta 1
25668 Cd38 CD38 molecule
Displaying entries 11 - 20 of 31 in total
Gene ID Gene Symbol Description Source
37104 Idgf5 Imaginal disc growth factor 5
37420 Ugt49B1 UDP-glycosyltransferase family 49 member B1
38288 oxt peptide O-xylosyltransferase
40079 Ugt316A1 UDP-glycosyltransferase family 316 member A1
41334 Ugt35A1 UDP-glycosyltransferase family 35 member A1
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
43222 Tl Toll
43223 Lerp lysosomal enzyme receptor protein
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
560951 xylt1 xylosyltransferase I
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
108703114 xylt1.S xylosyltransferase I S homeolog Xenopus laevis (African clawed frog)
Displaying all 5 entries
Gene ID Gene Symbol Description Source
175591 ugt-62 UDP-glucuronosyltransferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180628 cht-1 putative endochitinase
189173 W03G11.3 Putative alpha-L-fucosidase
190099 sqv-6 Xylosyltransferase sqv-6;protein xylosyltransferase
Displaying all 3 entries
Gene ID Gene Symbol Description Source
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024