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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 81 - 90 of 133 in total
Gene ID Gene Symbol Description Source
5327 PLAT plasminogen activator, tissue type
5444 PON1 paraoxonase 1
5551 PRF1 perforin 1
5644 PRSS1 serine protease 1
5798 PTPRN protein tyrosine phosphatase receptor type N
5799 PTPRN2 protein tyrosine phosphatase receptor type N2
5967 REG1A regenerating family member 1 alpha
6347 CCL2 C-C motif chemokine ligand 2
6352 CCL5 C-C motif chemokine ligand 5
6356 CCL11 C-C motif chemokine ligand 11
Displaying entries 1 - 10 of 102 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11423 Ache acetylcholinesterase
11450 Adipoq adiponectin, C1Q and collagen domain containing
11554 Adrb1 adrenergic receptor, beta 1
11596 Ager advanced glycosylation end product-specific receptor
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
11754 Aoc3 amine oxidase, copper containing 3
11814 Apoc3 apolipoprotein C-III
11998 Avp arginine vasopressin
12038 Bche butyrylcholinesterase
Displaying entry 61 - 61 of 61 in total
Gene ID Gene Symbol Description Source
316519 Slc11a1 solute carrier family 11 member 1
Displaying entries 11 - 20 of 43 in total
Gene ID Gene Symbol Description Source
35137 Ugt36F1 UDP-glycosyltransferase family 36 member F1
35138 Ugt36D1 UDP-glycosyltransferase family 36 member D1
35139 Ugt36E1 UDP-glycosyltransferase family 36 member E1
36232 Sod3 Superoxide dismutase 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
37420 Ugt49B1 UDP-glycosyltransferase family 49 member B1
37455 Egfr Epidermal growth factor receptor
38288 oxt peptide O-xylosyltransferase
39435 Tsf2 Transferrin 2
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024