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type 1 diabetes mellitus
Summary
- Synonym
-
- IDDM
- insulin-dependent diabetes mellitus
- type I diabetes mellitus
- Definition
- A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
- Super Class
- autoimmune disease of endocrine system diabetes mellitus
External Links
- Disease Ontology
- DOID:9744
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
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- 2386959
- 2663960
- 2680187
- 3038633
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- 4360179
- 4942396
- 5508894
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- 5565220
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- 5569019
- 5707775
- 5800315
- 7276257
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3251 | HPRT1 | hypoxanthine phosphoribosyltransferase 1 | |
| 3290 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | |
| 3291 | HSD11B2 | hydroxysteroid 11-beta dehydrogenase 2 | |
| 3295 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 | |
| 3339 | HSPG2 | heparan sulfate proteoglycan 2 | |
| 3383 | ICAM1 | intercellular adhesion molecule 1 | |
| 3481 | IGF2 | insulin like growth factor 2 | |
| 3482 | IGF2R | insulin like growth factor 2 receptor | |
| 3554 | IL1R1 | interleukin 1 receptor type 1 | |
| 3630 | INS | insulin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 11554 | Adrb1 | adrenergic receptor, beta 1 | |
| 12494 | Cd38 | CD38 antigen | |
| 12654 | Chi3l1 | chitinase 3 like 1 | |
| 14380 | G6pd2 | glucose-6-phosphate dehydrogenase 2 | |
| 14381 | G6pdx | glucose-6-phosphate dehydrogenase X-linked | |
| 16002 | Igf2 | insulin-like growth factor 2 | |
| 16177 | Il1r1 | interleukin 1 receptor, type I | |
| 16333 | Ins1 | insulin I | |
| 16334 | Ins2 | insulin II |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24375 | Fuca1 | alpha-L-fucosidase 1 | |
| 24377 | G6pd | glucose-6-phosphate dehydrogenase | |
| 24476 | Iapp | islet amyloid polypeptide | |
| 24483 | Igf2 | insulin-like growth factor 2 | |
| 24505 | Ins1 | insulin 1 | |
| 24506 | Ins2 | insulin 2 | |
| 24835 | Tnf | tumor necrosis factor | |
| 24861 | Ugt1a1 | UDP glucuronosyltransferase family 1 member A1 | |
| 24925 | Adrb1 | adrenoceptor beta 1 | |
| 25668 | Cd38 | CD38 molecule |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 444363 | xylt1.L | xylosyltransferase I L homeolog | Xenopus laevis (African clawed frog) | |
| 100135191 | ugt1a6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | Xenopus tropicalis (tropical clawed frog) | |
| 100145490 | xylt1 | xylosyltransferase I | Xenopus tropicalis (tropical clawed frog) | |
| 100489505 | ugt1a1 | UDP glucuronosyltransferase 1 family, polypeptide A1 | Xenopus tropicalis (tropical clawed frog) | |
| 108703114 | xylt1.S | xylosyltransferase I S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175591 | ugt-62 | UDP-glucuronosyltransferase | |
| 178046 | gspd-1 | Glucose-6-phosphate 1-dehydrogenase | |
| 180628 | cht-1 | putative endochitinase | |
| 189173 | W03G11.3 | Putative alpha-L-fucosidase | |
| 190099 | sqv-6 | Xylosyltransferase sqv-6;protein xylosyltransferase |
Related Glycoprotein
