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Standards Ontologies Notations
obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
External Links
Disease Ontology
DOID:9970
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 71 - 80 of 333 in total
Gene ID Gene Symbol Description Source
1634 DCN decorin
1636 ACE angiotensin I converting enzyme
1645 AKR1C1 aldo-keto reductase family 1 member C1
1646 AKR1C2 aldo-keto reductase family 1 member C2
1892 ECHS1 enoyl-CoA hydratase, short chain 1
2026 ENO2 enolase 2
2180 ACSL1 acyl-CoA synthetase long chain family member 1
2182 ACSL4 acyl-CoA synthetase long chain family member 4
2194 FASN fatty acid synthase
2215 FCGR3B Fc gamma receptor IIIb
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
11652 Akt2 thymoma viral proto-oncogene 2
11668 Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1
11815 Apod apolipoprotein D
12015 Bad BCL2-associated agonist of cell death
12846 Comt catechol-O-methyltransferase
12894 Cpt1a carnitine palmitoyltransferase 1a, liver
14380 G6pd2 glucose-6-phosphate dehydrogenase 2
14381 G6pdx glucose-6-phosphate dehydrogenase X-linked
14433 Gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying entries 21 - 27 of 27 in total
Gene ID Gene Symbol Description Source
64639 Bad BCL2-associated agonist of cell death
65038 Inppl1 inositol polyphosphate phosphatase-like 1
65248 Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1
83516 Ppargc1a PPARG coactivator 1 alpha
85496 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
94203 Pgf placental growth factor
297508 Nampt nicotinamide phosphoribosyltransferase
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32974 Zw Zwischenferment
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
37028 ACOX1 acyl-CoA oxidase 1
37447 Sdc Syndecan
39404 INPP5E Inositol polyphosphate 5-phosphatase E
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
44643 Cnx99A Calnexin 99A
Displaying 1 entry
Gene ID Gene Symbol Description Source
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
855480 ZWF1 glucose-6-phosphate dehydrogenase
Related Glycoprotein
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0001513 Obesity
HP:0000006 Autosomal dominant inheritance
HP:0010982 Polygenic inheritance
HP:0012340 Decreased resting energy expenditure
Displaying all 2 entries
Gene ID Gene Symbol Description
9672 SDC3 syndecan 3
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024