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MIRAGE
desmoglein 1
Summary
- Gene Symbol
-
- DSG1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Cytoplasm
- Glycoprotein
- Hypotrichosis
- Metal-binding
- Nucleus
- Palmoplantar keratoderma
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q02413 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell-cell junction assembly | ||
| homophilic cell adhesion via plasma membrane adhesion molecules | ||
| calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | ||
| response to progesterone | ||
| protein stabilization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding | ||
| calcium ion binding | ||
| protein binding | ||
| toxic substance binding | ||
| gamma-catenin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Desmoglein-1
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| calcium ion binding |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| InterPro |
|---|
| Cadherin conserved site |
| Cadherin-like superfamily |
| Cadherin-like |
| Catenin binding domain superfamily |
| Desmosomal cadherin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081108 | keratosis palmoplantaris striata 1 |
