GlyCosmos Portal

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
pyruvate kinase activity	ISO
pyruvate kinase activity	IDA	18062843 1834654 4273555 4353083 5492954
pyruvate kinase activity	IBA
pyruvate kinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

pyruvate kinase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding

small molecule binding [inference]

monosaccharide binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

alkali metal ion binding [inference]

potassium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

pyruvate_kinase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

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Gene Ontology
ATP binding
catalytic activity
cellular response to insulin stimulus
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
phosphorylation
potassium ion binding
pyruvate kinase activity

Displaying **all 9** entries
InterPro
Pyruvate kinase, C-terminal domain superfamily
Pyruvate kinase, C-terminal
Pyruvate kinase, active site
Pyruvate kinase, barrel
Pyruvate kinase, insert domain superfamily
Pyruvate kinase-like domain superfamily
Pyruvate kinase-like, insert domain superfamily
Pyruvate kinase
Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 67 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5313	Xenbase:XB-GENE-5918041	HUMAN52550
Saccharomyces cerevisiae S288C	5315	SGD:S000005874
Saccharomyces cerevisiae S288C	18746	SGD:S000000036
Mus musculus	18770		MOUSE38518
Xenopus tropicalis	24651	Xenbase:XB-GENE-5918041
Saccharomyces cerevisiae S288C	25630	SGD:S000005874
Xenopus tropicalis	42620	Xenbase:XB-GENE-5918041
Danio rerio	114551		DANRE11581
Takifugu rubripes	446067		TAKRU46373
Pan troglodytes	469513		PANTR22503

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Acknowledgements