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Repository for lectin-assisted multimodality data
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MIRAGE
interleukin 10
Summary
- Gene Symbol
-
- IL10
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Proteomics identification
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A286YEX3 |
|
| Q6FGW4 |
|
| P22301 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of cytokine production | ||
| positive regulation of cytokine production | ||
| positive regulation of endothelial cell proliferation | ||
| response to molecule of bacterial origin | ||
| chronic inflammatory response to antigenic stimulus |
GO Hierarchy
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- positive regulation of cytokine production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- positive regulation of cytokine production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- positive regulation of cytokine production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- positive regulation of cytokine production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- negative regulation of MHC class II biosynthetic process
- negative regulation of nitric oxide biosynthetic process
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
- positive regulation of cytokine production
- negative regulation of cytokine production involved in immune response
- negative regulation of type II interferon production
- negative regulation of interleukin-1 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-8 production
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
regulation of cytokine production [inference]
negative regulation of cytokine production
regulation of production of molecular mediator of immune response [inference]
regulation of DNA-templated transcription [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of metabolic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
regulation of cytokine production [inference]
negative regulation of cytokine production
regulation of production of molecular mediator of immune response [inference]
regulation of DNA-templated transcription [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
regulation of cytokine production [inference]
negative regulation of cytokine production
regulation of production of molecular mediator of immune response [inference]
regulation of DNA-templated transcription [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of metabolic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of cellular process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of programmed cell death [inference]
negative regulation of response to stimulus [inference]
negative regulation of multicellular organismal process [inference]
negative regulation of cytokine production
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
regulation of cytokine production [inference]
negative regulation of cytokine production
regulation of production of molecular mediator of immune response [inference]
regulation of DNA-templated transcription [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of gene expression [inference]
negative regulation of cytokine production
negative regulation of programmed cell death [inference]
regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
negative regulation of cytokine production
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
negative regulation of cytokine production
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| cytokine activity | ||
| cytokine activity | ||
| interleukin-10 receptor binding | ||
| protein binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11265 | trachoma | |
| DOID:12030 | panuveitis | |
| DOID:12132 | granulomatosis with polyangiitis | |
| DOID:12134 | factor VIII deficiency | |
| DOID:12361 | Graves' disease | |
| DOID:12894 | Sjogren's syndrome | |
| DOID:13141 | uveitis | |
| DOID:13241 | Behcet's disease | |
| DOID:14115 | toxic shock syndrome | |
| DOID:1417 | choroid disease |
