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MIRAGE

Chitin synthase 2

Summary

Gene Symbol

Chs2

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

40442

KEGG Gene ID

dme:Dmel_CG7464

PubChem

40442

Alliance of Genome Resources

FB:FBgn0029091

Annotation

Keyword

Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B7Z099
Q9VNW7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chitin biosynthetic process	ISS
chitin biosynthetic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

amino sugar metabolic process [inference]

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

glucosamine-containing compound metabolic process [inference]

chitin metabolic process [inference]

chitin biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
chitin synthase activity	ISS
chitin synthase activity	IBA
chitin synthase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

chitin synthase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

chitin synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Chitin synthase

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cell wall chitin biosynthetic process
chitin synthase activity
hexosyltransferase activity

Displaying **all 2** entries
InterPro
Chitin synthase
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K00698

Name

chitin synthase [EC:2.4.1.16]

References

16098962

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06028	2.4.1.16	G97099AY	G97099AY

Rhea

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.16

PMID

Ortholog

Displaying **all 10** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	40442	ZFIN:ZDB-GENE-060503-308
Danio rerio	45884	ZFIN:ZDB-GENE-060503-226
Danio rerio	172508	ZFIN:ZDB-GENE-060503-226
Danio rerio	173405	ZFIN:ZDB-GENE-060503-226
Caenorhabditis elegans	322468	WB:WBGene00000497
Danio rerio	563138	ZFIN:ZDB-GENE-060503-308
Danio rerio	563347	ZFIN:ZDB-GENE-060503-320
Danio rerio	852311	ZFIN:ZDB-GENE-060503-226
Danio rerio	852326	ZFIN:ZDB-GENE-060503-226
Danio rerio	101886093	ZFIN:ZDB-GENE-060503-226

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025