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aralar1

Summary

Gene Symbol

aralar1

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

43616

PubChem

43616

Alliance of Genome Resources

FB:FBgn0028646

Annotation

Keyword

Alternative splicing
Calcium
Metal-binding
Mitochondrion inner membrane
Proteomics identification
Reference proteome
Repeat
Transmembrane helix
Transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9VA73
A0A0B4KHW3
A0A0B4K6V1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

1

2

3

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GO Term	Evidence Code	PMID
gluconeogenesis	ISS
mitochondrial calcium ion transmembrane transport	IEA
aspartate transmembrane transport	IBA
gamma-aminobutyric acid transport	IGI	32200800
L-glutamate transmembrane transport	IDA	33497735

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular process [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

mitochondrial transport [inference]

mitochondrial calcium ion transmembrane transport

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

gamma-aminobutyric acid transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

gamma-aminobutyric acid transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

gamma-aminobutyric acid transport

amide transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	HDA	19317464
mitochondrial inner membrane	IC	33497735

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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2

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GO Term	Evidence Code	PMID
3-sulfino-L-alanine: proton, glutamate antiporter activity	IDA	33497735
aspartate:glutamate, proton antiporter activity	IDA	33497735
L-glutamate transmembrane transporter activity	IBA
calcium ion binding	ISS
calcium ion binding	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

gamma-aminobutyric acid transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

amino acid transmembrane transporter activity [inference]

sulfur amino acid transmembrane transporter activity [inference]

sulfur-containing amino acid secondary active transmembrane transporter activity [inference]

3-sulfino-L-alanine: proton, glutamate antiporter activity

amino acid:monoatomic cation symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

acidic amino acid transmembrane transporter activity [inference]

neutral L-amino acid transmembrane transporter activity [inference]

3-sulfino-L-alanine: proton, glutamate antiporter activity

L-amino acid transmembrane transporter activity [inference]

gamma-aminobutyric acid transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

amino acid:monoatomic cation antiporter activity [inference]

C4-dicarboxylate transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

gamma-aminobutyric acid transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

amino acid transmembrane transporter activity [inference]

sulfur amino acid transmembrane transporter activity [inference]

sulfur-containing amino acid secondary active transmembrane transporter activity [inference]

3-sulfino-L-alanine: proton, glutamate antiporter activity

amino acid:monoatomic cation symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

acidic amino acid transmembrane transporter activity [inference]

neutral L-amino acid transmembrane transporter activity [inference]

3-sulfino-L-alanine: proton, glutamate antiporter activity

L-amino acid transmembrane transporter activity [inference]

gamma-aminobutyric acid transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

amino acid:monoatomic cation antiporter activity [inference]

C4-dicarboxylate transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

solute:proton symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

solute:proton symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

amino acid:monoatomic cation antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

solute:proton symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

amino acid:monoatomic cation antiporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

solute:proton symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

solute:proton symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

antiporter activity [inference]

amino acid:monoatomic cation antiporter activity [inference]

secondary active monocarboxylate transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

sulfur-containing amino acid secondary active transmembrane transporter activity [inference]

3-sulfino-L-alanine: proton, glutamate antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

solute:proton symporter activity [inference]

amino acid:proton symporter activity [inference]

gamma-aminobutyric acid:proton symporter activity

amino acid:monoatomic cation antiporter activity [inference]

amide transmembrane transporter activity [inference]

modified amino acid transmembrane transporter activity [inference]

3-sulfino-L-alanine: proton, glutamate antiporter activity

sulfur compound transmembrane transporter activity [inference]

sulfur amino acid transmembrane transporter activity [inference]

sulfur-containing amino acid secondary active transmembrane transporter activity [inference]

3-sulfino-L-alanine: proton, glutamate antiporter activity

salt transmembrane transporter activity [inference]

binding [inference]

protein binding [inference]

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mitochondrial carrier

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
L-aspartate transmembrane transporter activity
L-glutamate transmembrane transporter activity
calcium ion binding
malate-aspartate shuttle

Displaying **all 6** entries
InterPro
EF-Hand 1, calcium-binding site
EF-hand domain pair
EF-hand domain
Mitochondrial carrier domain superfamily
Mitochondrial carrier protein
Mitochondrial substrate/solute carrier

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
membrane	FB:FBrf0231198
mitochondrion	PMID:19317464

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070341	neonatal-onset type II citrullinemia	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	8604	Xenbase:XB-GENE-1002100
Xenopus tropicalis	10165	Xenbase:XB-GENE-1013331
Xenopus tropicalis	43616	Xenbase:XB-GENE-1002100
Xenopus tropicalis	50799	Xenbase:XB-GENE-1013331

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements