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ER lipid raft associated 2 S homeolog

Summary

Gene Symbol

erlin2.S

Organism

Xenopus laevis (African clawed frog)

External Links

NCBI Gene

444675

PubChem

444675

Alliance of Genome Resources

Xenbase:XB-GENE-6254593

Annotation

Keyword

Cholesterol metabolism
Endoplasmic reticulum
Glycoprotein
Reference proteome
Signal
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A974D7P0	Endoplasmic reticulum lipid raft-associated protein Stomatin-prohibitin-flotillin-HflC/K domain-containing protein
Q6DKC0	Endoplasmic reticulum lipid raft-associated protein 2-B Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol metabolic process	IEA
SREBP signaling pathway

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

signal transduction [inference]

ER-nucleus signaling pathway [inference]

SREBP signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

response to stimulus [inference]

response to stress [inference]

response to sterol depletion [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

ER-nucleus signaling pathway [inference]

SREBP signaling pathway

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol binding
ubiquitin protein ligase binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

small molecule binding [inference]

alcohol binding [inference]

cholesterol binding

organic cyclic compound binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Erlin

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cholesterol binding
ubiquitin protein ligase binding

Displaying **all 3** entries
InterPro
Band 7 domain
Band 7/SPFH domain superfamily
Erlin1/2

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	11160	Xenbase:XB-GENE-950144
Xenopus tropicalis	178178	Xenbase:XB-GENE-950144
Xenopus tropicalis	244373	Xenbase:XB-GENE-950144
Xenopus tropicalis	290823	Xenbase:XB-GENE-950144
Xenopus tropicalis	444675	Xenbase:XB-GENE-950144
Xenopus tropicalis	495100	Xenbase:XB-GENE-950144
Xenopus tropicalis	549473	Xenbase:XB-GENE-950144
Xenopus tropicalis	100151163	Xenbase:XB-GENE-950144