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adhesion G protein-coupled receptor L4

Summary

Gene Symbol

ADGRL4

Organism

Homo sapiens (human)

External Links

NCBI Gene

64123

PubChem

64123

Alliance of Genome Resources

HGNC:20822

Annotation

Keyword

Calcium
Cell membrane
Disulfide bond
EGF-like domain
G-protein coupled receptor
Glycoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9HBW9	EGF, latrophilin and seven transmembrane domain-containing protein 1 EGF-TM7-latrophilin-related protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	TAS	15203201
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	IBA
membrane	TAS	15203201
cytoplasmic vesicle	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IBA
calcium ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G-protein coupled receptor Mth-like 1

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

Displaying **all 6** entries
InterPro
EGF-like calcium-binding domain
GAIN domain superfamily
GAIN domain, N-terminal
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM
GPS motif

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	976	FB:FBgn0033313
Drosophila melanogaster	2015	FB:FBgn0033313
Drosophila melanogaster	13733	FB:FBgn0033313
Drosophila melanogaster	22859	FB:FBgn0033313
Drosophila melanogaster	23266	FB:FBgn0033313
Drosophila melanogaster	23284	FB:FBgn0033313
Danio rerio	35846	ZFIN:ZDB-GENE-040426-2689
Xenopus laevis	64123	Xenbase:XB-GENE-17338314
Rattus norvegicus	64124	ZFIN:ZDB-GENE-040426-2689	RATNO23890
Drosophila melanogaster	65096	FB:FBgn0033313