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toll like receptor 2
Summary
- Gene Symbol
-
- TLR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Isopeptide bond
- Leucine-rich repeat
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| O60603 |
|
| A0A0S2Z4S4 |
|
| B3KWR9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of non-canonical NF-kappaB signal transduction | ||
| defense response to Gram-positive bacterium | ||
| positive regulation of inflammatory response | ||
| inflammatory response | ||
| cellular response to bacterial lipopeptide |
GO Hierarchy
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
biological process
immune system process [inference]
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to external stimulus [inference]
response to biotic stimulus [inference]
response to chemical [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to cytokine stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| receptor complex | ||
| cell body | ||
| cytoplasm | ||
| Toll-like receptor 1-Toll-like receptor 2 protein complex | ||
| cell surface |
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane signaling receptor activity | ||
| NAD+ nucleotidase, cyclic ADP-ribose generating | ||
| amyloid-beta binding | ||
| lipopolysaccharide binding | ||
| Toll-like receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:684 | hepatocellular carcinoma | |
| DOID:783 | end stage renal disease | |
| DOID:850 | lung disease | |
| DOID:8534 | gastroesophageal reflux disease | |
| DOID:8677 | perinatal necrotizing enterocolitis | |
| DOID:869 | cholesteatoma | |
| DOID:874 | bacterial pneumonia | |
| DOID:8741 | seborrheic dermatitis | |
| DOID:8867 | molluscum contagiosum | |
| DOID:8893 | psoriasis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100860747 | CAPHI08115 | ||
| 554262 | SHEEP07113 | ||
| 100009578 | RABIT05050 | ||
| 24088 | MGI:1346060 | MOUSE36900 | |
| 310553 | RGD:735138 | RATNO23011 | |
| 100717682 | CAVPO04663 | ||
| 100024558 | MONDO27939 | ||
| 100564001 | ANOCA07706 | ||
| 103658031 | URSMA09511 | ||
| 114046537 | VOMUR10869 |
