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signal-induced proliferation-associated 1 like 3

Summary

Gene Symbol

Sipa1l3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74206

PubChem

74206

Alliance of Genome Resources

MGI:1921456

Annotation

Keyword

Acetylation
Cell membrane
Coiled coil
GTPase activation
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
G3X9J0	SPA-1-like protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
eye development	IMP	26231217
hematopoietic progenitor cell differentiation	IMP	24029230
epithelial cell morphogenesis	ISO
epithelial cell morphogenesis	IMP	26231217
epithelial cell morphogenesis	IBA

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity [inference]

establishment of cell polarity [inference]

establishment of epithelial cell polarity

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

epithelial cell morphogenesis

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

eye development

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

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GO Term	Evidence Code	PMID
stress fiber	ISS
stress fiber	ISO
nucleoplasm	ISO
nucleoplasm	IEA
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

tricellular tight junction

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

postsynaptic specialization, intracellular component

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular non-membrane-bounded organelle [inference]

postsynaptic specialization, intracellular component

apical part of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
GTPase activator activity	IBA
GTPase activator activity	IEA

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

signal-induced proliferation-associated 1

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
regulation of small GTPase mediated signal transduction

Displaying **all 4** entries
InterPro
PDZ domain
PDZ superfamily
Rap/Ran-GAP domain
Rap/Ran-GAP superfamily

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	6494	WB:WBGene00012100
Homo sapiens	23094	ZFIN:ZDB-GENE-050420-109	HUMAN43147
Caenorhabditis elegans	26037	WB:WBGene00012100
Caenorhabditis elegans	57568	WB:WBGene00012100
Danio rerio	74206	ZFIN:ZDB-GENE-050420-109
Caenorhabditis elegans	217692	WB:WBGene00012100
Caenorhabditis elegans	244668	WB:WBGene00012100
Rattus norvegicus	292771		RATNO19376
Pan troglodytes	468861		PANTR18153
Bos taurus	513625		BOVIN10984