calreticulin

Summary
Gene Symbol
  • CALR
Aliases
  • CRT
  • FLJ26680
  • RO
  • SSA
  • Sicca syndrome antigen A (autoantigen Ro; calreticulin)
  • autoantigen Ro
  • cC1qR
  • calregulin
Organism
Homo sapiens (human)
External Links
NCBI Gene
811
HGNC
1455
KEGG Gene ID
hsa:811
PubChem
811
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Calcium
  • Chaperone
  • Cytoplasm
  • Cytoplasmic vesicle
  • Direct protein sequencing
  • Disulfide bond
  • Endoplasmic reticulum
  • Extracellular matrix
  • Glycoprotein
  • Hydroxylation
  • Lectin
  • Lysosome
  • Metal-binding
  • Reference proteome
  • Repeat
  • Sarcoplasmic reticulum
  • Signal
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
P27797
  • CRP55
  • Calregulin
  • Endoplasmic reticulum resident protein 60
  • HACBP
  • grp60
V9HW88
Gene Ontology (GO)
Displaying entries 41 - 42 of 42 in total
GO Term Evidence Code PMID
response to estradiol
peptide antigen assembly with MHC class I protein complex
GO Hierarchy
GO Hierarchy
Human Protein Atlas
ENSG00000179218

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K08057
Name
calreticulin
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 410 in total
DO ID Disease Name Source
DOID:11678 onchocerciasis
DOID:11729 Lyme disease
DOID:2615 papilloma
DOID:850 lung disease
DOID:0060303 complement component 9 deficiency
DOID:0060319 cardiac arrest
DOID:0040085 bacterial sepsis
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050424 familial adenomatous polyposis
DOID:0050458 juvenile myelomonocytic leukemia
The Human Phenotype Ontology
Displaying entries 11 - 20 of 72 in total
HPO ID HPO Term
HP:0001409 Portal hypertension
HP:0001433 Hepatosplenomegaly
HP:0001442 Typified by somatic mosaicism
HP:0001541 Ascites
HP:0001658 Myocardial infarction
HP:0001744 Splenomegaly
HP:0001824 Weight loss
HP:0001871 Abnormality of blood and blood-forming tissues
HP:0001872 Abnormality of thrombocytes
HP:0001873 Thrombocytopenia
Displaying all 5 entries
Disease ID Disease Name
ORPHA:824
  • primary myelofibrosis
OMIM:254450
  • primary myelofibrosis
ORPHA:3318
  • essential thrombocythemia
OMIM:187950
  • thrombocythemia 1
ORPHA:131
  • Budd-Chiari syndrome

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024