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internexin neuronal intermediate filament protein alpha

Summary

Gene Symbol

INA

Organism

Homo sapiens (human)

External Links

NCBI Gene

9118

PubChem

9118

Alliance of Genome Resources

HGNC:6057

Annotation

Keyword

Acetylation
Coiled coil
Developmental protein
Differentiation
Direct protein sequencing
Glycoprotein
Intermediate filament
Neurogenesis
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q16352	66 kDa neurofilament protein Neurofilament 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
intermediate filament organization	IBA
cell differentiation	IEA
neurofilament cytoskeleton organization	IEA
substantia nigra development	HEP	22926577
postsynaptic intermediate filament cytoskeleton organization	IEA

GO Hierarchy

biological process

cellular process [inference]

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization [inference]

cellular developmental process [inference]

cell differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization [inference]

postsynaptic cytoskeleton organization [inference]

postsynaptic intermediate filament cytoskeleton organization

supramolecular fiber organization [inference]

intermediate filament organization

developmental process [inference]

anatomical structure development [inference]

neural nucleus development [inference]

substantia nigra development

cellular developmental process [inference]

cell differentiation

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
intermediate filament	IBA
neurofilament	IEA
postsynaptic intermediate filament cytoskeleton	IBA
cytoplasm	IBA
extracellular space	HDA	22664934

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell junction [inference]

synapse [inference]

Schaffer collateral - CA1 synapse

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

neurofilament

Displaying **all 3** entries
GO Term	Evidence Code	PMID
structural constituent of postsynaptic intermediate filament cytoskeleton	IBA
protein binding	IPI	28514442 32814053 33961781 36931259 37207277
structural constituent of cytoskeleton	TAS	7769995

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of cytoskeleton

structural constituent of postsynaptic intermediate filament cytoskeleton

structural constituent of synapse [inference]

structural constituent of postsynapse [inference]

structural constituent of postsynaptic intermediate filament cytoskeleton

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	1674	WB:WBGene00002058
Caenorhabditis elegans	2670	WB:WBGene00002058
Caenorhabditis elegans	3855	WB:WBGene00002058
Caenorhabditis elegans	3856	WB:WBGene00002058
Caenorhabditis elegans	3872	WB:WBGene00002058
Caenorhabditis elegans	5630	WB:WBGene00002058
Caenorhabditis elegans	7431	WB:WBGene00002058
Caenorhabditis elegans	8687	WB:WBGene00002058
Xenopus tropicalis	9118	Xenbase:XB-GENE-492716
Caenorhabditis elegans	13346	WB:WBGene00002058