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Glycan Structure Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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Guidelines
MIRAGE
Pro-epidermal growth factor
Summary
- UniProt ID
- P01133
- Gene Symbol
-
- EGF
- Gene ID
- 1950
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P01133
- PubChem
- P01133
- The Human Metabolome Database
- HMDBP02438
- The O-GlcNAc Database
- P01133
- Re-Glyco
- P01133
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Primary hypomagnesemia
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
Sequence
MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPHQMELTQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 38 | N-linked (GlcNAc...) asparagine |
|
||
| 104 | N-linked (GlcNAc...) asparagine | |||
| 117 | N-linked (GlcNAc...) asparagine |
|
||
| 148 | N-linked (GlcNAc...) asparagine | |||
| 324 | N-linked (GlcNAc...) asparagine |
|
||
| 404 | N-linked (GlcNAc...) asparagine |
|
||
| 596 | N-linked (GlcNAc...) asparagine |
|
||
| 801 |
|
|||
| 807 |
|
|||
| 815 | N-linked (GlcNAc...) asparagine |
|
G83460ZZ
G80920RR
G62765YT
G64527OM
G05724UK
G31852PQ
G82020ZR
G02815KT
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PI3K/AKT Signaling | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
| PLCG1 events in ERBB2 signaling | Homo sapiens |
| Platelet degranulation | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| SHC1 events in EGFR signaling | Homo sapiens |
| SHC1 events in ERBB2 signaling | Homo sapiens |
| Signaling by EGFR | Homo sapiens |
| Signaling by ERBB2 | Homo sapiens |
| Signaling by ERBB2 ECD mutants | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050782 | Zollinger-Ellison syndrome | |
| DOID:0060879 | primary hypomagnesemia | |
| DOID:0060882 | renal hypomagnesemia 4 | |
| DOID:1380 | endometrial cancer | |
| DOID:3068 | glioblastoma | |
| DOID:3070 | high grade glioma | |
| DOID:3121 | gallbladder cancer | |
| DOID:3181 | oligodendroglioma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma |
