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Pro-epidermal growth factor

Summary

UniProt ID

P01133

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlyConnect

GlyGen

P01133

PubChem

P01133

The Human Metabolome Database

HMDBP02438

The O-GlcNAc Database

P01133

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disease variant
Disulfide bond
EGF-like domain
Glycoprotein
Growth factor
Primary hypomagnesemia
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 33 in total

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GO Term
positive regulation of DNA-templated transcription
positive regulation of canonical Wnt signaling pathway
positive regulation of phosphorylation
positive regulation of mitotic nuclear division
branching morphogenesis of an epithelial tube
epithelial cell proliferation
negative regulation of secretion
positive regulation of epithelial tube formation
cerebellar granule cell precursor proliferation
positive regulation of cerebellar granule cell precursor proliferation

Displaying **all 7** entries
GO Term
clathrin-coated endocytic vesicle membrane
platelet alpha granule lumen
lysosomal membrane
extracellular exosome
extracellular region
extracellular space
plasma membrane

Displaying **all 6** entries
GO Term
calcium ion binding
transmembrane receptor protein tyrosine kinase activator activity
guanyl-nucleotide exchange factor activity
growth factor activity
receptor ligand activity
epidermal growth factor receptor binding

Annotation information from UniProt.

Sequence

MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPHQMELTQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine		UniProt GlyGen
104	N-linked (GlcNAc...) asparagine	G83460ZZ G80920RR G62765YT G64527OM G05724UK G31852PQ G82020ZR G02815KT	UniProt GlyGen GlyConnect
117	N-linked (GlcNAc...) asparagine		UniProt GlyGen
148	N-linked (GlcNAc...) asparagine	G83460ZZ G80920RR G62765YT	UniProt GlyGen
324	N-linked (GlcNAc...) asparagine		UniProt GlyGen
404	N-linked (GlcNAc...) asparagine		UniProt GlyGen
596	N-linked (GlcNAc...) asparagine		UniProt GlyGen
801		G43417UB	GlyGen
807		G43417UB	GlyGen
815	N-linked (GlcNAc...) asparagine		UniProt GlyGen