Interleukin-1 alpha

Summary
UniProt ID
P01583
Gene Symbol
  • IL1A
  • IL1F1
Gene ID
3552
Organism
Homo sapiens (human)
PubChem
P01583
Re-Glyco
P01583
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Cytokine
  • Cytoplasm
  • Direct protein sequencing
  • Glycoprotein
  • Mitogen
  • Myristate
  • Nucleus
  • Phosphoprotein
  • Pyrogen
  • Reference proteome
  • Secreted
Gene Ontology (GO)
Sequence
MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
102 N-linked (GlcNAc...) asparagine
141 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 7 entries
Pathway Name Organism
Interleukin-1 processing Homo sapiens
Interleukin-1 signaling Homo sapiens
Interleukin-10 signaling Homo sapiens
Interleukin-4 and Interleukin-13 signaling Homo sapiens
Purinergic signaling in leishmaniasis infection Homo sapiens
Pyroptosis Homo sapiens
Senescence-Associated Secretory Phenotype (SASP) Homo sapiens
Disease
Displaying entries 11 - 18 of 18 in total
DO ID Disease Name Source
DOID:676 juvenile rheumatoid arthritis
DOID:7148 rheumatoid arthritis
DOID:783 end stage renal disease
DOID:8924 autoimmune thrombocytopenic purpura
DOID:9119 acute myeloid leukemia
DOID:9383 iridocyclitis
DOID:9538 multiple myeloma
DOID:9744 type 1 diabetes mellitus

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025