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Standards Ontologies Notations
Platelet glycoprotein Ib alpha chain

Summary
UniProt ID
P07359
Gene Symbol
  • GP1BA
Organism
Homo sapiens (human)
External Links
GlyConnect
GlyGen
P07359
PubChem
P07359
RaftProt
P07359
Annotation
Keyword
  • 3D-structure
  • Bernard Soulier syndrome
  • Cell adhesion
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Leucine-rich repeat
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
  • Sulfation
  • Transmembrane helix
  • von Willebrand disease
Gene Ontology (GO)
Displaying 1 entry
GO Term
thrombin-activated receptor activity
Annotation information from UniProt.
Sequence
MPLLLLLLLLPSPLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDTEGDKVRATRTVVKFPTKAHTTPWGLFYSWSTASLDSQMPSSLHPTQESTKEQTTFPPRWTPNFTLHMESITFSKTPKSTTEPTPSPTTSEPVPEPAPNMTTLEPTPSPTTPEPTSEPAPSPTTPEPTSEPAPSPTTPEPTSEPAPSPTTPEPTPIPTIATSPTILVSATSLITPKSTFLTTTKPVSLLESTKKTIPELDQPPKLRGVLQGHLESSRNDPFLHPDFCCLLPLGFYVLGLFWLLFASVVLILLLSWVGHVKPQALDSGQGAALTTATQTTHLELQRGRQVTVPRAWLLFLRGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLSTVSIRYSGHSL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 46 in total
Position Description PubMed ID GlyTouCan ID Source
37 N-linked (GlcNAc...) asparagine
175 N-linked (GlcNAc...) asparagine
308 O-linked (GalNAc...) threonine
316 O-linked (GalNAc...) threonine
320 O-linked (GalNAc...) threonine
321 O-linked (GalNAc...) threonine
328 O-linked (GalNAc...) serine
331 O-linked (GalNAc...) threonine
340 O-linked (GalNAc...) serine
341 O-linked (GalNAc...) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 8 entries
Pathway Name Organism
Defective F9 activation Homo sapiens
Defective binding of VWF variant to GPIb:IX:V Homo sapiens
Enhanced binding of GP1BA variant to VWF multimer:collagen Homo sapiens
GP1b-IX-V activation signalling Homo sapiens
Intrinsic Pathway of Fibrin Clot Formation Homo sapiens
Platelet Adhesion to exposed collagen Homo sapiens
Platelet Aggregation (Plug Formation) Homo sapiens
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Homo sapiens
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024