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Tyrosine-protein phosphatase non-receptor type 11

Summary

UniProt ID

P35235

Gene Symbol

Ptpn11

Organism

Mus musculus (house mouse)

External Links

GlyGen: P35235
PubChem: P35235

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
Phosphoprotein
Protein phosphatase
Reference proteome
Repeat
SH2 domain

Gene Ontology (GO)

Displaying entries **1 - 10** of 53 in total

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GO Term
axonogenesis
organ growth
hormone metabolic process
glucose homeostasis
positive regulation of ossification
positive regulation of mitotic cell cycle
positive regulation of glucose import
negative regulation of insulin secretion
positive regulation of hormone secretion
negative regulation of hormone secretion

Displaying **all 5** entries
GO Term
protein-containing complex
plasma membrane raft
cytosol
nucleus
cytoplasm

Displaying entries **1 - 10** of 16 in total

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GO Term
phosphotyrosine residue binding
D1 dopamine receptor binding
peptide hormone receptor binding
protein tyrosine phosphatase activity
insulin receptor binding
protein kinase binding
protein domain specific binding
signaling receptor complex adaptor activity
receptor tyrosine kinase binding
phospholipase binding

Annotation information from UniProt.

Sequence

MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
217			G41840AI	GlyGen
566				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 20** of 37 in total

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Pathway Name	Organism
Interleukin-20 family signaling	Mus musculus
Interleukin-3, Interleukin-5 and GM-CSF signaling	Mus musculus
Interleukin-6 signaling	Mus musculus
MAPK1 (ERK2) activation	Mus musculus
MAPK3 (ERK1) activation	Mus musculus
MET activates PTPN11	Mus musculus
Negative regulation of FGFR1 signaling	Mus musculus
Negative regulation of FGFR2 signaling	Mus musculus
Negative regulation of FGFR3 signaling	Mus musculus
Negative regulation of FGFR4 signaling	Mus musculus