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Tyrosine-protein phosphatase non-receptor type 11

Summary

UniProt ID

P35235

Gene Symbol

Ptpn11

Organism

Mus musculus (house mouse)

External Links

GlyGen: P35235
PubChem: P35235
The O-GlcNAc Database: P35235

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
Phosphoprotein
Protein phosphatase
Reference proteome
Repeat
SH2 domain

Gene Ontology (GO)

Displaying entries **1 - 10** of 54 in total

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GO Term
lipid metabolic process
signal transduction
axonogenesis
positive regulation of signal transduction
glucose homeostasis
multicellular organismal reproductive process
hormone-mediated signaling pathway
cerebellar cortex formation
platelet formation
negative regulation of chondrocyte differentiation

Displaying **all 5** entries
GO Term
nucleus
cytoplasm
protein-containing complex
cytosol
plasma membrane raft

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GO Term
protein kinase binding
cadherin binding
cell adhesion molecule binding
protein domain specific binding
D1 dopamine receptor binding
peptide hormone receptor binding
protein tyrosine kinase binding
phospholipase binding
insulin receptor substrate binding
phosphotyrosine residue binding

Annotation information from UniProt.

Sequence

MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
217			G41840AI	GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Interleukin-20 family signaling	Mus musculus
Interleukin-3, Interleukin-5 and GM-CSF signaling	Mus musculus
Interleukin-6 signaling	Mus musculus
MAPK1 (ERK2) activation	Mus musculus
MAPK3 (ERK1) activation	Mus musculus
MET activates PTPN11	Mus musculus
Negative regulation of FGFR1 signaling	Mus musculus
Negative regulation of FGFR2 signaling	Mus musculus
Negative regulation of FGFR3 signaling	Mus musculus
Negative regulation of FGFR4 signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements