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Signal transducer and activator of transcription 1

Summary

UniProt ID

P42225

Gene Symbol

Stat1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P42225
PubChem: P42225
The O-GlcNAc Database: P42225
RaftProt: P42225

Annotation

Keyword

ADP-ribosylation
Acetylation
Activator
Coiled coil
Cytoplasm
DNA-binding
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Reference proteome
SH2 domain
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 36 in total

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GO Term
positive regulation of mesenchymal cell proliferation
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
defense response
blood circulation
cell population proliferation
response to bacterium
cytokine-mediated signaling pathway
regulation of cell population proliferation
macrophage derived foam cell differentiation
response to cytokine

Displaying **all 6** entries
GO Term
nucleus
cytoplasm
nucleoplasm
axon
dendrite
cytosol

Displaying **all 9** entries
GO Term
DNA binding
protein phosphatase 2A binding
CCR5 chemokine receptor binding
protein homodimerization activity
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MSQWFELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAAYDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPVQMSMIIYNCLKEERKILENAQRFNQAQEGNIQNTVMLDKQKELDSKVRNVKDQVMCIEQEIKTLEELQDEYDFKCKTSQNREGEANGVAKSDQKQEQLLLHKMFLMLDNKRKEIIHKIRELLNSIELTQNTLINDELVEWKRRQQSACIGGPPNACLDQLQTWFTIVAETLQQIRQQLKKLEELEQKFTYEPDPITKNKQVLSDRTFLLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKSRLLVKLQESNLLTKVKCHFDKDVNEKNTVKGFRKFNILGTHTKVMNMEESTNGSLAAELRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVTEPRNLSFFLNPPCAWWSQLSEVLSWQFSSVTKRGLNADQLSMLGEKLLGPNAGPDGLIPWTRFCKENINDKNFSFWPWIDTILELIKNDLLCLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDDPKRTGYIKTELISVSEVHPSRLQTTDNLLPMSPEEFDEMSRIVGPEFDSMMSTV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 15 in total

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Pathway Name	Organism
Downstream signal transduction	Mus musculus
ISG15 antiviral mechanism	Mus musculus
Interferon alpha/beta signaling	Mus musculus
Interferon gamma signaling	Mus musculus
Interleukin-20 family signaling	Mus musculus
Interleukin-21 signaling	Mus musculus
Interleukin-27 signaling	Mus musculus
Interleukin-35 Signalling	Mus musculus
Interleukin-4 and Interleukin-13 signaling	Mus musculus
Interleukin-6 signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Annotation

International Collaboration

Acknowledgements