|
Regulation of FZD by ubiquitination
|
|
|
- FZD5
- FZD6
- FZD8
- LGR5
- LRP5
- LRP6
- RNF43
- RPS27A
- RSPO1
- RSPO2
- RSPO3
- RSPO4
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- USP8
- WNT3A
|
|
|
Recycling of bile acids and salts
|
|
|
- ABCB11
- ABCC3
- ALB
- FABP6
- NCOA1
- NCOA2
- NR1H4
- OSTA
- OSTB
- RXRA
- SLC10A1
- SLC10A2
- SLC27A5
- SLC51A
- SLC51B
- SLCO1A2
- SLCO1B3
- STARD5
|
|
|
Endogenous sterols
|
|
|
- ADX
- AHR
- ARNT
- ARNT2
- CYP11A1
- CYP11B1
- CYP19A1
- CYP1B1
- CYP21
- CYP21A1
- CYP21A2
- CYP27A1
- CYP39A1
- CYP46A1
- CYP4V2
- CYP51A1
- CYP7A1
- FDX1
- FDX1L
- FDX2
- FDXR
- LOC112449566
- NCOA1
- NCOA2
- NR1H4
- POMC
- RXRA
|
|
|
PKA activation
|
|
|
- ADCY1
- ADCY2
- ADCY3
- ADCY4
- ADCY5
- ADCY6
- ADCY8
- ADCY9
- CALM
- PRKACA
- PRKACB
- PRKAR1A
- PRKAR1B
- PRKAR2A
|
|
|
Adenosine P1 receptors
|
|
|
- ADORA1
- ADORA2A
- ADORA2B
- ADORA3
|
|
|
Atorvastatin ADME
|
|
|
- ABCB1
- ABCC2
- CYP3A28
- CYP3A4
- CYP3A5
- CYP3A74
- PON1
- PON3
- SLCO1B3
- SLCO2B1
- UGT1A1
|
|
|
Separation of Sister Chromatids
|
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome non-ATPase regulatory subunit 12
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 1
- 26S proteasome non-ATPase regulatory subunit 2
- 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 8
- 26S proteasome regulatory subunit 6B
- 26S proteasome regulatory subunit 7
- 26S proteasome regulatory subunit 8
- AT-hook containing transcription factor 1
- Alpha isoform of regulatory subunit A, protein phosphatase 2
- Anaphase promoting complex subunit 1
- Anaphase promoting complex subunit 7
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 15
- Anaphase-promoting complex subunit 16
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
- Anaphase-promoting complex subunit CDC26
- Aurora kinase
- B9 domain-containing protein 2
- BUB1 mitotic checkpoint serine/threonine kinase B
- BUB1 protein
- Baculoviral IAP repeat-containing protein 5
- Borealin
- CAP-Gly domain containing linker protein 1
- CENPI protein
- CENPP protein
- Cell division cycle 16
- Cell division cycle 20
- Cell division cycle associated 5
- Cell division cycle protein 23 homolog
- Cell division cycle protein 27 homolog
- Centromere protein C
- Centromere protein E
- Centromere protein F
- Centromere protein H
- Centromere protein K
- Centromere protein L
- Centromere protein M
- Centromere protein N
- Centromere protein O
- Centromere protein Q
- Centromere protein S
- Centromere protein T
- Cohesin subunit SA
- Cohesin subunit SA
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic linker associated protein 1
- Cytoplasmic linker associated protein 2
- Cytoskeleton associated protein 5
- DNA excision repair protein ERCC-6-like
- DSN1 component of MIS12 kinetochore complex
- Double-strand-break repair protein rad21 homolog
- Dynein heavy chain, cytosolic
- Dynein light chain 1, cytoplasmic
- Dynein light chain 2, cytoplasmic
- Dynein light intermediate chain
- Dynein light intermediate chain
- E2 ubiquitin-conjugating enzyme
- Exportin 1
- Histone H3-like centromeric protein A
- Histone deacetylase 8
- Inner centromere protein
- Integrin subunit beta 3 binding protein
- Kinesin-like protein
- Kinetochore associated 1
- Kinetochore protein NDC80
- Kinetochore protein Spc24
- Kinetochore protein Spc25
- Kinetochore scaffold 1
- Microtubule-associated protein RP/EB family member 1
- Mitotic arrest deficient 1 like 1
- Mitotic arrest deficient 2 like 1
- Mitotic checkpoint protein BUB3
- NDE1 protein
- NSL1 protein
- NUF2 component of NDC80 kinetochore complex
- NUP43 protein
- Nuclear distribution protein nudE-like 1
- Nuclear migration protein nudC
- Nuclear pore complex protein Nup85
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein
- Nucleoporin 133
- Nucleoporin 160
- Nucleoporin 37
- Nucleoporin SEH1
- PDS5 cohesin associated factor A
- PDS5 cohesin associated factor B
- Platelet-activating factor acetylhydrolase IB subunit alpha
- Polyamine-modulated factor 1
- Polyubiquitin-B
- Polyubiquitin-C
- Proteasomal ubiquitin receptor ADRM1
- Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14
- Proteasome 26S subunit, ATPase 3
- Proteasome 26S subunit, ATPase 6
- Proteasome subunit alpha type-1
- Proteasome subunit alpha type-2
- Proteasome subunit alpha type-3
- Proteasome subunit alpha type-4
- Proteasome subunit alpha type-5
- Proteasome subunit alpha type-6
- Proteasome subunit alpha type-7
- Proteasome subunit beta type-2
- Proteasome subunit beta type-3
- Proteasome subunit beta type-4
- Proteasome subunit beta type-5
- Proteasome subunit beta type-6
- Proteasome subunit beta
- Proteasome subunit beta
- Protein MIS12 homolog
- Protein SEC13 homolog
- Protein Spindly
- Protein phosphatase 2 scaffold subunit Abeta
- Protein zwilch homolog
- RAN binding protein 2
- RCC2 protein
- Ran GTPase activating protein 1
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Shugoshin 1
- Shugoshin 2
- Small ribosomal subunit protein eS27
- Spindle and kinetochore-associated protein 1
- Structural maintenance of chromosomes protein 1A
- Structural maintenance of chromosomes protein
- Ubiquitin-conjugating enzyme E2 C
- Ubiquitin-conjugating enzyme E2 D1
- Ubiquitin-conjugating enzyme E2 S
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
- WAPL cohesin release factor
- ZW10 interacting kinetochore protein
- ZW10, kinetochore associated, homolog (Drosophila)
- non-specific serine/threonine protein kinase
- separase
|
|
- ADRM1
- AHCTF1
- ANAPC1
- ANAPC10
- ANAPC11
- ANAPC15
- ANAPC16
- ANAPC2
- ANAPC4
- ANAPC5
- ANAPC7
- ANAPC8
- APITD1
- AURKB
- B9D2
- BIRC5
- BUB1
- BUB1B
- BUB3
- CCDC99
- CDC16
- CDC20
- CDC23
- CDC26
- CDC27
- CDCA5
- CDCA8
- CENPC
- CENPE
- CENPF
- CENPH
- CENPI
- CENPK
- CENPL
- CENPM
- CENPO
- CENPP
- CENPQ
- CENPS
- CENPT
- CKAP5
- CLASP1
- CLASP2
- CLIP1
- DNCL1
- DSN1
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- ERCC6L
- ESPL1
- FAAP16
- HDAC8
- INCENP
- ITGB3BP
- KIF2B
- KNL1
- KNTC1
- LIS1
- MAD1L1
- MAD2L1
- MAPRE1
- MCM21R
- MHF1
- MIS12
- NDC80
- NDE1
- NDEL1
- NSL1
- NUDC
- NUF2
- NUP107
- NUP133
- NUP160
- NUP37
- NUP43
- NUP85
- NUP98
- PAFAH1B1
- PDS5A
- PDS5B
- PLK1
- PMF1
- PPP1CC
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5D
- PPP2R5E
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RAD21
- RANBP2
- RANGAP1
- RCC2
- RPS27
- RPS27A
- SCC1
- SEC13
- SEC13L1
- SEH1L
- SGO1
- SGO2
- SKA1
- SMC1
- SMC1A
- SMC1L1
- SMC3
- SPBC25
- SPC24
- SPC25
- SPDL1
- STAG1
- STAG2
- SUG1
- TAOK1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBCH10
- UBE2C
- UBE2D1
- UBE2E1
- UBE2S
- WAPL
- XPO1
- ZW10
- ZWILCH
- ZWINT
|
|
|
FGFR1c and Klotho ligand binding and activation
|
|
|
|
|
|
Bicarbonate transporters
|
|
|
- AHCYL2
- SLC4A1
- SLC4A10
- SLC4A2
- SLC4A3
- SLC4A4
- SLC4A5
- SLC4A7
- SLC4A8
- SLC4A9
|
|
|
Glycerophospholipid biosynthesis
|
|
|
- AGK
- CPNE1
- CPNE3
- CPNE6
- CPNE7
|
|
|
Phospholipase C-mediated cascade; FGFR3
|
|
|
- AFGF
- FGF1
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF6A
- FGF8
- FGF9
- FGFA
- FGFR3
- Fgf4
- HBGF-1
- PLCG1
|
|
|
Metal ion SLC transporters
|
|
|
- CP
- HEPH
- SLC11A1
- SLC11A2
- SLC30A10
- SLC40A1
- SLC41A1
- SLC41A2
|
|
|
Adrenaline,noradrenaline inhibits insulin secretion
|
|
|
- ADCY5
- ADCY6
- ADRA2A
- ADRA2C
- GNAI1
- GNAI2
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNGT1
- GNGT12
- GNGT2
- GNGT3
- GNGT5
- GNGT7
- GNGT8
|
|
|
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
|
|
|
- GABBR1
- GABBR2
- GIRK1
- GIRK4
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNGT1
- GNGT12
- GNGT2
- GNGT3
- GNGT5
- GNGT7
- GNGT8
- IRK1
- KCNJ10
- KCNJ12
- KCNJ15
- KCNJ16
- KCNJ2
- KCNJ3
- KCNJ4
- KCNJ5
- KCNJ6
|
|
|
Trafficking and processing of endosomal TLR
|
|
|
- CNPY3
- CTSB
- CTSK
- CTSL
- CTSL1
- CTSS
- GRP94
- HSP90B1
- HSPC4
- LGMN
- TLR3
- TLR7
- TLR9
- TRA1
- UNC93B1
|
|
|
MAPK6/MAPK4 signaling
|
|
|
- ADRM1
- BORG1
- CCND3
- CDC14A
- CDC14B
- CDC2
- CDC42
- CDC42EP2
- CDC42EP3
- CDC42EP5
- CDK1
- CDKN1
- CEP2
- DNAJB1
- ETV4
- FOXO1
- FOXO3
- HSP27
- HSPB1
- MAPK4
- MAPK6
- MAPKAPK5
- NCOA3
- PAK1
- PAK2
- PAK3
- PRKACA
- PRKACB
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RPS27A
- SEPTIN7
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- XPO1
|
|
|
COPI-dependent Golgi-to-ER retrograde traffic
|
|
|
- ARCN1
- ARF1
- ARF3
- ARF4
- ARF5
- ARFGAP1
- ARFGAP2
- ARFGAP3
- BNIP1
- CENPE
- COPA
- COPB1
- COPB2
- COPD
- COPE
- COPE1
- COPG1
- COPG2
- COPZ
- COPZ1
- COPZ2
- GBF1
- KDELR
- KDELR1
- KDELR2
- KDELR3
- KIF11
- KIF12
- KIF13B
- KIF15
- KIF16B
- KIF18B
- KIF1B
- KIF1C
- KIF20A
- KIF20B
- KIF21A
- KIF21B
- KIF22
- KIF23
- KIF25
- KIF26B
- KIF28
- KIF2B
- KIF3A
- KIF5A
- KIF5B
- KLC1
- KLC2
- KLC3
- KLC4
- NAPA
- NAPB
- NAPG
- NBAS
- NSF
- RAB1A
- RAB1B
- RACGAP1
- RINT1
- SEC22B
- SNAPB
- STX18
- SURF4
- TMED10
- TMED3
- TMED7
- TMED9
- TMP21
- USE1
- ZW10
|
|
|
Adherens junctions interactions
|
|
|
- AFDN
- ANG2
- CADM1
- CADM2
- CADM3
- CDH1
- CDH10
- CDH11
- CDH12
- CDH13
- CDH15
- CDH17
- CDH18
- CDH2
- CDH24
- CDH3
- CDH4
- CDH5
- CDH6
- CDH7
- CDH8
- CTNNA1
- CTNNB1
- CTNND1
- JUP
- NECTIN1
- NECTIN2
- NECTIN3
- PVRL4
- RAA2
|
|
|
The NLRP3 inflammasome
|
|
|
- HSP90AB1
- HSPC3
- HSPCB
- NLRP3
- P2RX7
- PANX
- PANX1
- PSTPIP1
- PYCARD
- SUGT1
- TXN
- TXNIP
|
|
|
PI-3K cascade:FGFR3
|
|
|
- AFGF
- FGF1
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF6A
- FGF8
- FGF9
- FGFA
- FGFR3
- FRS2
- Fgf4
- GAB1
- GRB2
- HBGF-1
- PIK3CA
- PIK3R1
- PTPN11
|
|
|
Glycosphingolipid catabolism
|
|
|
- ARSA
- ARSB
- ARSE
- ARSG
- ARSH
- ARSI
- ARSK
- ASAH1
- ASAH2
- CTSA
- ENPP7
- GALC
- GBA1
- GBA2
- GBA3
- GLA
- GLB1
- GLB1L
- GLB1L2
- GM2A
- HEXA
- HEXB
- M6PR
- NEU1
- NEU2
- NEU3
- NEU4
- PSAP
- SMPD1
- SMPD3
- SMPD4
- STS
- SUMF1
- SUMF2
|
|
|
WNT ligand biogenesis and trafficking
|
|
|
- SNX3
- TMED5
- VPS26A
- VPS29
- VPS35
- WLS
- WNT1
- WNT10A
- WNT10B
- WNT11
- WNT16
- WNT2
- WNT2B
- WNT3
- WNT3A
- WNT4
- WNT5A
- WNT6
- WNT7A
- WNT7B
- WNT8A
- WNT8B
- WNT9B
|
|
|
RHOBTB2 GTPase cycle
|
|
|
- ACTG
- ACTG1
- ACTN1
- BAT1
- CCT2
- CCT6A
- CCT7
- CDC37
- CUL3
- DDX39B
- HNRPC
- HSP90A
- HSP90AA1
- HSP90AB1
- HSPC3
- HSPCA
- HSPCB
- MYO6
- PHIP
- RBMX
- RHOBTB2
- SFRS10
- SRRM1
- STK38
- TMOD3
- TRA2B
- TWF1
- TXNL1
- UAP56
|
|
|
Regulation of RUNX2 expression and activity
|
|
|
- ADRM1
- CUL1
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RPS27A
- RUNX2
- SKP1
- SKP1A
- SKP2
- STUB1
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
|
Thyroxine biosynthesis
|
|
|
- CGA
- DUOX1
- DUOX2
- IYD
- SLC5A5
- TPO
- TSHB
|
|