GlyCosmos Portal

Bos taurus (domestic cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (2220) Glycans (1011) Glycoproteins (1219) Lectins (76) Pathways (548)

Displaying entries **451 - 475** of **548** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
The activation of arylsulfatases	ARSB protein ARSE protein Arylsulfatase A Arylsulfatase G Arylsulfatase K Arylsulfatase family member H Arylsulfatase family member I Formylglycine-generating enzyme Inactive C-alpha-formylglycine-generating enzyme 2 Steroid sulfatase	A0A3Q1LZ44 A5D7J7 A6QLZ3 E1BIN3 F1N665 G3N2T7 Q08DD1 Q0P5L5 Q148F3 Q58CP2	ARSA ARSB ARSE ARSG ARSH ARSI ARSK STS SUMF1 SUMF2
Voltage gated Potassium channels	A-type voltage-gated potassium channel KCND1 A-type voltage-gated potassium channel KCND2 KCNF1 protein Potassium voltage-gated channel modifier subfamily G member 1 Potassium voltage-gated channel modifier subfamily G member 2 Potassium voltage-gated channel modifier subfamily G member 3 Potassium voltage-gated channel modifier subfamily G member 4 Potassium voltage-gated channel modifier subfamily S member 2 Potassium voltage-gated channel modifier subfamily V member 2 Potassium voltage-gated channel subfamily A member 10 Potassium voltage-gated channel subfamily A member 2 Potassium voltage-gated channel subfamily A member 3 Potassium voltage-gated channel subfamily A member 4 Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily A member 6 Potassium voltage-gated channel subfamily A member 7 Potassium voltage-gated channel subfamily A regulatory beta subunit 3 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily B member 2 Potassium voltage-gated channel subfamily C member 1 Potassium voltage-gated channel subfamily C member 3 Potassium voltage-gated channel subfamily C member 4 Potassium voltage-gated channel subfamily D member 3 Potassium voltage-gated channel subfamily H member 2 Potassium voltage-gated channel subfamily H member 3 Potassium voltage-gated channel subfamily H member 4 Potassium voltage-gated channel subfamily H member 5 Potassium voltage-gated channel subfamily H member 6 Potassium voltage-gated channel subfamily H member 7 Potassium voltage-gated channel subfamily H member 8 Potassium voltage-gated channel subfamily KQT member 1 Potassium voltage-gated channel subfamily KQT member 3 Potassium voltage-gated channel subfamily Q member 2 Potassium voltage-gated channel subfamily Q member 4 Potassium voltage-gated channel subfamily Q member 5 Potassium voltage-gated channel subfamily S member 1 Voltage-gated delayed rectifier potassium channel KCNH1 Voltage-gated potassium channel subunit beta-1 Voltage-gated potassium channel subunit beta-2	A0A3Q1LSF6 A0A3Q1M6H7 A0A3Q1MFH2 A0A3Q1MPE6 A0A3Q1MT75 A2VDT0 A4FV89 E1B760 E1B7K3 E1B9N0 E1BC13 E1BCM0 E1BDC5 E1BII8 E1BKI8 E1BLH0 E1BMA2 F1MC54 F1MDM5 F1MFZ3 F1MJA9 F1MKB0 F1ML52 F1MP51 F1MPV7 F1MTJ1 F1MVI5 F1MY95 F1N0E8 F1N4A4 F1N553 G3N1T8 G3N279 O18965 P58126 Q27955 Q4PJK1 Q4ZHA6 Q52PG9	EAG1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNAB1 KCNAB2 KCNAB3 KCNB1 KCNB2 KCNC1 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNV2 KVB2
Glutathione synthesis and recycling	Cytosolic non-specific dipeptidase Gamma-glutamylcyclotransferase Gamma-glutamylcyclotransferase Glutamate--cysteine ligase regulatory subunit Glutamate--cysteine ligase Glutathione hydrolase 7 Glutathione hydrolase Glutathione hydrolase Glutathione synthetase Putative glutathione-specific gamma-glutamylcyclotransferase 2	A0A140T850 A0A3Q1MN33 A6H738 F1MYJ3 G3N2D8 Q0IIH4 Q0V8L2 Q2T9Y6 Q32LE4 Q3ZC84	CHAC1 CHAC2 CNDP2 GCLC GCLM GGCT GGT1 GGT5 GGT7 GGTL3 GSS
FGFR2c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1LRU7 A0MTF4 D8KXU9 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6 FGF6A FGF7B FGF8 FGF9 FGFA FGFR2 Fgf4 HBGF-1
RHO GTPases Activate NADPH Oxidases	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Protein S100-A8 Protein S100-A9 Protein kinase C beta type Protein kinase C delta type Protein kinase C Ras-related C3 botulinum toxin substrate 2 non-specific serine/threonine protein kinase	A0A3Q1LQK4 A0A3Q1LTT9 A0A3Q1MKI4 A0A3Q1MRR6 A0A3Q1MSP9 A0A3Q1MTW8 A0A452DHY1 A6QLW1 E1B8P9 E1BAA4 E1BFF3 E1BPJ7 F1MHS5 G3X793 O46521 O46522 P05126 P28782 P46196 Q5BIN5 Q9TU25	CYBA CYBB ERK2 MAPK1 MAPK11 MAPK14 MAPK3 NCF1 NCF2 NCF4 NOX1 NOX3 NOXO1 PIK3C3 PIK3R4 PIN1 PRKCB PRKCB1 PRKCD PRKCZ PRKM1 RAC2 S100A8 S100A9
Caspase-mediated cleavage of cytoskeletal proteins	Adducin 1 Caspase 7 Caspase 8 Caspase-3 Caspase-6 GAS2 protein Gelsolin Plectin Sorbin and SH3 domain containing 2 Spectrin alpha, non-erythrocytic 1 Vimentin	A0A3Q1LNC8 A0A3Q1MRS3 A0A3Q1MUK3 A8E4Q5 E1BHK2 F1MB04 F1MD58 F1N1I6 G3X702 P48616 Q2LGB8	ADD1 CASP3 CASP6 CASP7 CASP8 GAS2 GSN PLEC SORBS2 SPTAN1 VIM
Clathrin-mediated endocytosis	ADP ribosylation factor GTPase activating protein 1 AP-1 complex subunit beta-1 AP-2 complex subunit alpha-2 AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma AP2 associated kinase 1 Actin nucleation-promoting factor WASL Actin related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Amphiphysin Amphiregulin Apolipoprotein B Arginine vasopressin Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Betacellulin Bridging integrator 1 CD4 molecule Cation-dependent mannose-6-phosphate receptor Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Cyclin G associated kinase Cystic fibrosis transmembrane conductance regulator DAB adaptor protein 2 Dishevelled segment polarity protein 2 DnaJ heat shock protein family (Hsp40) member C6 Dynamin-1 E3 ubiquitin-protein ligase CBL EPS15 protein Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epiregulin Epithelial mitogen Epsin 1 Epsin 2 F-BAR domain only protein 2 FCH and mu domain containing endocytic adaptor 1 Formin binding protein 1 Formin-binding protein 1-like GTPase-activating protein and VPS9 domain-containing protein 1 Growth factor receptor-bound protein 2 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin interacting protein 1 related Huntingtin interacting protein 1 Insulin like growth factor 2 receptor Interleukin-7 receptor subunit alpha Intersectin 1 Intersectin 2 KIAA0319 LDL receptor related protein 2 LDLRAP1 protein Low-density lipoprotein receptor Muscarinic acetylcholine receptor M2 NECAP endocytosis associated 2 Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Polyubiquitin-B Polyubiquitin-C Proheparin-binding EGF-like growth factor Protein Wnt Protein kinase C and casein kinase substrate in neurons 2 Protein kinase C and casein kinase substrate in neurons 3 Protein kinase C and casein kinase substrate in neurons protein 1 RALBP1 associated Eps domain containing 1 Ras-related protein Rab-5A Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain containing kinase binding protein 1 Scavenger receptor class B member 2 Serotransferrin Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Solute carrier family 18 member A3 Solute carrier family 2 member 8 Sorting nexin Sorting nexin Stonin-1 Stonin-2 Substance-P receptor Synaptosome associated protein 91 Synaptotagmin 11 Synaptotagmin 8 Synaptotagmin 9 Synaptotagmin-1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain Thyroid hormone receptor interactor 10 Trans-golgi network protein 2 Transferrin receptor protein 1 Transforming growth factor alpha Type-1 angiotensin II receptor Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vasopressin V2 receptor Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 4 Vesicle-associated membrane protein 8 dynamin GTPase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase small monomeric GTPase	A0A3Q1LK58 A0A3Q1LN00 A0A3Q1LPM3 A0A3Q1LVF9 A0A3Q1LXE7 A0A3Q1LXY0 A0A3Q1M7J4 A0A3Q1M808 A0A3Q1M839 A0A3Q1MAH6 A0A3Q1MBL1 A0A3Q1MG95 A0A3Q1MHB0 A0A3Q1MIC9 A0A3Q1MKW3 A0A3Q1ML18 A0A3Q1MMI6 A0A3Q1MSK9 A0A3Q1MSZ4 A0A3Q1MWJ5 A0A3Q1NNG9 A0A3S5ZPN6 A2VDU0 A2VE27 A4IFN6 A4IFV0 A5D794 A5D7I1 A7MB62 A7MBI0 E1BBE2 E1BDG5 E1BDM2 E1BDP2 E1BE68 E1BIG6 E1BIN8 E1BJ14 E1BK36 E1BK71 E1BKY4 E1BNR0 E1BPM3 F1MBY5 F1MC50 F1MEV4 F1MGT4 F1MI54 F1MIB2 F1MIE6 F1MIX5 F1MJK4 F1MN01 F1MNI4 F1MRS2 F1MSM9 F1MUI0 F1MWF0 F1MX23 F1MZ25 F1MZY9 F1N1U1 F1N371 F1N4I2 F1N579 F1N6H1 F1N6W6 F6Q4T4 F6RJ01 F6RS49 G3MXC8 G3X6N3 G3X811 G8JL01 P01131 P04973 P04975 P0CG53 P0CH28 P11456 P17870 P19120 P25104 P41985 P48018 P48044 P49951 P61157 P62992 P63026 P63048 Q08DF4 Q08DS7 Q08DX1 Q0IIG7 Q0V8S0 Q0VCK5 Q148J6 Q17QC5 Q1JP79 Q1RMR9 Q28044 Q28072 Q2KJA1 Q32L97 Q3MHR7 Q3T035 Q3T093 Q3T0F9 Q3T0Y8 Q3ZC13 Q95107	AAK1 ACTR2 ACTR3 ADRB2 AGTR1 AMPH AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB AREG ARFGAP1 ARP2 ARP3 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARRB1 ARRB2 AVP AVPR2 BIN1 BTC CBL CD3D CD3G CD4 CFTR CHRM2 CLTA CLTB CLTC CLTLB DAB2 DNAJC6 DNM1 DNM3 DVL2 EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EREG FCHO1 FCHO2 FNBP1 FNBP1L GAK GAPVD1 GRB2 HBEGF HGS HIP1 HIP1R HSC70 HSPA8 IGF2R IL7R ITSN1 ITSN2 KIAA0319 LDLR LDLRAP1 LRP2 M6PR NECAP1 NECAP2 OCRL PACSIN1 PACSIN2 PACSIN3 PIK3C2A PIP5K1C RAB5A RAB5B REPS1 RPS27A SCARB2 SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 STAM STAM2 STON1 STON2 SYB2 SYNJ2 SYT1 SYT11 SYT8 SYT9 TACR1 TF TFRC TGFA TRIP10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VAMP2 VAMP4 VAMP8 WASL WNT5A
FRS-mediated FGFR3 signaling	FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A3Q1MPT9 A0MTF4 A5D7R9 A6H792 D8KXU9 E1B7I9 E1BJU2 E1BMX0 E1BP37 F1MHC6 F1N339 F1N6G8 F1N7C3 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 Q3T0F9	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 FRS2 FRS3 Fgf4 GRB2 HBGF-1 KRAS NRAS PTPN11 SOS1
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Myc proto-oncogene protein Transcription factor AP-2 gamma [histone H3]-trimethyl-L-lysine(4) demethylase	F1MUR2 Q0VC14 Q2HJ27	KDM5B MYC TFAP2C
Regulation of RUNX3 expression and activity	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta Runt-related transcription factor Transforming growth factor beta-1 proprotein Tyrosine-protein kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein histone acetyltransferase	A0A3Q1LJ39 A0A3Q1MYL2 A0A3Q1N449 A1L5A6 A7MBA2 E1B8D6 E1B9S8 E1BIM8 F1MBI1 F1MLS5 F1MLV1 F1MWE0 F1MXE4 F1MYE6 F1MYH8 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2YDE4 Q32KL2 Q3MHN0 Q3T030 Q3T0X5 Q3T0Y5 Q3T108 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9K0	ADRM1 CBFB EP300 MDM2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A RUNX3 SMURF1 SMURF2 SRC SUG1 TGFB1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
SHC-mediated cascade:FGFR2	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 A5D7R9 D8KXU9 E1BGY3 E1BHC1 E1BJU2 E1BMX0 E1BP37 F1MHC6 F1N6G8 F1N7C3 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 Q0IIE2 Q3T0F9	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 Fgf4 GRB2 HBGF-1 KRAS NRAS SHC1 SOS1
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Beta-1,4-galactosyltransferase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 (Neuroglycan C) Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Hexosyltransferase Neurocan Syndecan-1 Syndecan-2 Syndecan Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	A0A3Q1LG25 A0A3Q1LSF3 A0A3Q1LTY7 A0A3Q1LZ29 E1BKJ2 E1BKS1 F1MCX1 F1MQ31 F1MQ60 F1MVH6 F1MY84 F1MZX8 F1N211 F1N2Y8 F6Q1U8 P21793 P21809 P81282 Q08DZ5 Q0VCM1 Q3ZBZ6 Q58DD4	AGRN B3GALT6 B3GAT1 B3GAT3 B4GALT7 BCAN BGN CSPG2 CSPG4 CSPG5 DCN GPC1 GPC2 GPC3 GPC4 GPC5 NCAN SDC1 SDC2 SDC4 VCAN XYLT1 XYLT2
Interferon gamma signaling	Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Y-box-binding protein 1 calcium/calmodulin-dependent protein kinase	A0A3Q1LLQ7 A0A3Q1M739 A0A3Q1ME65 A0A3Q1MKC7 A0A3Q1MRR6 E1B8P9 E1BCP6 F1MSN0 F1MXR5 F1N0D6 P07353 P46196 P67808 Q2HJF7 Q3MHJ9 Q9BEG9	CAMK2A CAMK2B CAMK2D ERK2 IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 PRKCD PRKM1 PTPN6 SOCS1 SOCS3 STAT1 YB1 YBX1
Apoptotic execution phase	B-cell receptor-associated protein Caspase 8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A2VE07 Q2KIA5 Q2LGB8 Q5E9F1	BCAP31 CASP8 DNM1L STK24
G alpha (12/13) signalling events	A-kinase anchoring protein 13 Active breakpoint cluster region-related protein Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor FGD1 family, member 3 FGD1 protein FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 4 G protein subunit alpha 12 G protein subunit alpha 13 G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Intersectin 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Neuroepithelial cell transforming 1 Neuronal guanine nucleotide exchange factor Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G5 Plexin B1 Proto-oncogene vav Rac/Cdc42 guanine nucleotide exchange factor 6 Ras protein specific guanine nucleotide releasing factor 2 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-associated protein kinase 2 Rho-associated protein kinase Rho-related GTP-binding protein RhoC Rho/Rac guanine nucleotide exchange factor 18 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 TIAM Rac1 associated GEF 2 Thromboxane A2 receptor Transforming protein RhoA Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 non-specific serine/threonine protein kinase	A0A3Q1LFQ5 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LUW4 A0A3Q1LXW7 A0A3Q1M851 A0A3Q1M8D9 A0A3Q1MA22 A0A3Q1MA88 A0A3Q1MA97 A0A3Q1MAT2 A0A3Q1MD11 A0A3Q1MIT6 A0A3Q1MN47 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MW77 A0A3Q1N5A2 A0A3Q1N5H1 A0A3Q1N6F4 A0A3Q1NGS8 A0A3S5ZPL0 A4IFL6 A5D7I5 A5PKD6 A6QNS3 E1B7F6 E1B7M1 E1B7W0 E1B8Q3 E1B9G8 E1BBD2 E1BDY4 E1BH05 E1BIL1 E1BIM5 E1BKY4 E1BP14 E1BQ24 F1MBM9 F1MF50 F1MGA6 F1MJ96 F1MLS2 F1MM93 F1MPJ6 F1MSU8 F1MYW8 F1N0Q1 F1N1J9 F1N1Q7 F1N2G5 F1N7C3 G5E6P3 P02698 P11017 P30671 P50154 P61585 P62871 P63212 P63214 P63217 Q08DA6 Q08DN7 Q0P5E3 Q1RMJ6 Q28024 Q3SZ98 Q3ZC95 Q58CS5 Q5E9F0 Q95125	ABR ADRA1A ADRA1B ADRA1D AKAP13 ARHA ARHC ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF26 ARHGEF3 ARHGEF33 ARHGEF37 ARHGEF38 ARHGEF39 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BTK FGD1 FGD2 FGD3 FGD4 GNA12 GNA13 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 ITSN1 L2HGDH MCF2L NET1 NGEF PLEKHG2 PLEKHG5 PLXNB1 PREX1 RASGRF2 RHO12 RHOA RHOC ROCK1 ROCK2 SOS1 SOS2 TBXA2R TIAM2 TRIO VAV1 VAV2 VAV3
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	G1K218 P07455 P07456	IGF1 IGF1R IGF2
RHOF GTPase cycle	A-kinase anchoring protein 12 Actin, cytoplasmic 1 Actin, cytoplasmic 2 Adducin 3 Alpha-actinin-1 Anion exchange protein BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain containing adaptor protein 2 like 2 Brain acid soluble protein 1 Caveolin-1 DEP domain containing 1B Diaphanous related formin 1 Diaphanous related formin 2 Diaphanous related formin 3 FERM, ARHGEF and pleckstrin domain-containing protein 1 Family with sequence similarity 169 member A Family with sequence similarity 62 (C2 domain containing), member A Lamin B1 Melanoma cell adhesion molecule Myosin IXB Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Rho GTPase activating protein 12 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho-related GTP-binding protein RhoF SLIT-ROBO Rho GTPase activating protein 2 STEAP3 metalloreductase SUMO specific peptidase 1 Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein Torsin-1A-interacting protein 1 Vang-like protein	A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LNG7 A0A3Q1LPT9 A0A3Q1LUD9 A0A3Q1M6Y9 A0A3Q1MFX1 A0A3Q1MRR8 A0A3Q1MSB2 A0A3Q1NDE1 A0A452DIN5 A0JN43 E1BFE6 E1BHQ9 E1BLB3 E1BM23 E1BMN2 E1BNR7 E1BNV7 F1MFC6 F1MXR0 F1MXU4 F1N4E5 F1N5F9 F1N7Q8 F6RWK1 G3MWI1 P23726 P23727 P60712 P63258 P79132 P80724 Q2T9M8 Q3B7N2 Q3SZA1	ACTB ACTG ACTG1 ACTN1 ADD3 AKAP12 ARHGAP1 ARHGAP12 ARHGAP32 ARHGAP39 ARHGAP5 BAIAP2L1 BAIAP2L2 BASP1 CAV1 DEPDC1B DIAPH1 DIAPH2 DIAPH3 FAM169A FAM62A FARP1 LMNB1 MCAM MTMR1 MYO9B NAP22 PIK3R1 PIK3R2 RHOF SENP1 SLC4A7 SNAP23 SRGAP2 STEAP3 SYDE1 TOR1AIP1 VANGL1
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase 5-formyltetrahydrofolate cyclo-ligase C-1-tetrahydrofolate synthase, cytoplasmic Dihydrofolate reductase Folate receptor 2 (Fetal) Folylpolyglutamate synthase Methylenetetrahydrofolate reductase Monofunctional C1-tetrahydrofolate synthase, mitochondrial Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase, mitochondrial Serine hydroxymethyltransferase Solute carrier family 25 member 32 methenyltetrahydrofolate cyclohydrolase methenyltetrahydrofolate cyclohydrolase	A0A140T872 A0A140T896 A0A3Q1MU29 A0A3Q1NGK6 A0A452DI11 A4FUD0 E1BDG9 E1BMG9 E1BNJ2 F1MWN5 G3X7X2 Q05B81 Q0VCN9 Q0VCR7 Q1RMT3 Q3SZ20	ALDH1L1 ALDH1L2 DHFR FOLR2 FPGS HCP1 MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS PCFT SHMT1 SHMT2 SLC19A1 SLC25A32 SLC46A1
Translocation of ZAP-70 to Immunological synapse	BOLA-DQA1 protein BoLA-DR-alpha CD4 molecule Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II antigen Major histocompatibility complex, class II, DY alpha T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain TRAV29-1*01 Tyrosine-protein kinase Tyrosine-protein kinase protein-tyrosine-phosphatase	A0A3Q1M088 A0A3Q1M3D2 A0A3Q1MT21 A6H6Y1 A6QQE7 E1BLZ1 E1BMP9 F1MJK4 F1MJU5 F1ML60 F1N0X9 F1N6L3 G3MWT2 G8JL01 Q0VCU4 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BoLA-DIB BoLA-DRA BoLA-DYB CD247 CD3D CD3E CD3G CD4 DYB HLA-DRA LCK LOC100848815 PTPN22 TRAV29-1 ZAP70
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Integrin beta-2 Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type dynamin GTPase	A0A3Q1MIC9 A0A3Q1MMD9 A0A3Q1MZF3 A6QNL0 C4T7Z1 E1BJR7 F1MFI2 F1MNN7 G3MYD9 P17453 P32592 Q08DF4 Q2LGB7 Q6WCD5	BPI CD14 CD18 CD180 DNM1 DNM3 ITGAM ITGB2 LBP LY86 LY96 MD-2 PLCG2 PTPN4 TICAM2 TLR4 TRAM
HDL clearance	Apolipoprotein A-I Cubilin High density lipoprotein binding protein Protein amnionless Scavenger receptor class B member 1	A0A3Q1MUD4 F1MKV7 F1MQD9 O18824 P15497	AMN APOA1 CUBN HDLBP SCARB1
Sphingolipid de novo biosynthesis	Broad substrate specificity ATP-binding cassette transporter ABCG2 CYB5B protein Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Ceramide transfer protein Fatty acid 2-hydroxylase MFSD2 lysolipid transporter B, sphingolipid Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein Phosphatidylcholine Protein phosphatase, Mg2+/Mn2+ dependent 1L SPTLC2 protein Serine palmitoyltransferase 1 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase Serine/threonine-protein kinase Serine/threonine-protein kinase Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase 2 Sphingosine kinase 1 Sphingosine kinase 2 Sterile alpha motif domain containing 8 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase	A0A3Q1MBG6 A0A3Q1MJ30 A0A3Q1MVP2 A0A3Q1N9F5 A0A452DJG0 A2VDZ9 A4FUG2 A5D7K4 A5PKM3 A7MB90 B2D1N9 E1B7L9 E1B7T6 E1BGC2 E1BNX6 E1BPW1 F1MF31 F1MIA2 F1MXZ6 F1MYS1 Q0II71 Q0IIK4 Q0P5F6 Q0VCY1 Q0VD15 Q29RQ9 Q3MHG1 Q3ZBF8 Q3ZBY7 Q5E972 Q5E978 Q5E9R6 Q8HXQ5 Q9GKI7	ABCC1 ABCG2 ADMP CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CERT CERT1 COL4A3BP CSNK1G2 CYB5B DEGS1 DEGS2 DES1 FA2H LASS1 LASS2 LASS3 LASS4 MFSD2B MRP1 ORMDL1 ORMDL2 ORMDL3 OSBP PPM1L PRKD1 PRKD2 PRKD3 SAMD8 SGMS1 SGMS2 SPHK1 SPHK2 SPTLC1 SPTLC2 SPTSSA SPTSSB SSSPTA SSSPTB STARD11 VAPA VAPB
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-mannosidase Alpha-mannosidase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Fucosyltransferase Glycoprotein hormones alpha chain Lutropin subunit beta Tissue alpha-L-fucosidase	A0A3Q1M1B8 C0LMH8 E1BB36 E1BGJ4 F1MBS8 F1N4H9 F1N7T2 P01217 P04651 Q2KIM0	CGA CHST10 CHST8 FUCA1 FUT6 FUT8 LHB MAN2A1 MAN2A2 MGAT2	G70323CJ G82576YO
Interleukin-2 signaling	Cytokine receptor common subunit gamma Interleukin-2 receptor subunit alpha Interleukin-2 SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific protein-tyrosine kinase	A0A140T878 A0A3Q1LVP1 A0A3Q1MHG9 A2VE30 E1BEL4 F1N0D6 P05016 Q0IIE2 Q3ZCM0 Q95115 Q95118	IL-2 IL2 IL2RA IL2RG JAK1 JAK3 LCK MGF PTK2B SHC1 STAT5A STAT5B SYK
Na+/Cl- dependent neurotransmitter transporters	Sodium- and chloride-dependent GABA transporter 2 Sodium-dependent neutral amino acid transporter B(0)AT2 Solute carrier family 18 (Vesicular monoamine), member 2 Solute carrier family 18 member A1 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter	A0A3Q1M4L9 A0A3Q1MVF2 A0A3Q1NLB0 A0JND1 A1A4L2 A5PJX7 A6QLU4 A7MBE0 B0JYP2 E1BHC0 E1BHW6 E1BPI1 F1MAX1 F1MBH3 F1N5R0 G5E6L1 Q9XS59	B0AT2 NTT73 OCT1 SLC18A1 SLC18A2 SLC22A1 SLC22A2 SLC6A1 SLC6A11 SLC6A13 SLC6A15 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A5 SLC6A6 SLC6A7 SLC6A9

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