GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Orc1 removal from chromatin	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 BRCT domain-containing protein CDT1 Geminin-binding domain-containing protein Cell division control protein Cullin-1 Cyclin-dependent kinase 2 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM7 DNA replication licensing factor mcm-4 DNA replication licensing factor mcm-5 DNA replication licensing factor mcm-6 F-box domain-containing protein G2/mitotic-specific cyclin-A1 GNAT family N-acetyltransferase MPN domain-containing protein ORC (Origin Recognition Complex) subunit Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 5 C-terminal domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 RING-box protein 1 Skp1-related protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A131MD44 G5ECU1 O16297 O16368 O17071 O17586 O44156 O61742 O61792 O61847 O62102 O76371 O76577 P0CG71 P34638 P34647 P37165 P46502 P49632 P90868 P91155 P91477 Q04908 Q09397 Q10920 Q17389 Q17971 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q21037 Q21902 Q22253 Q22319 Q23237 Q23249 Q23449 Q23457 Q27488 Q86S68 Q95005 Q95008 Q95PZ7 Q95XQ8 Q966I8 Q9GZH5 Q9N599 Q9XTT9 Q9XUV0 Q9XVR7 Q9XX16 Q9XX17 Q9XXI9	C14C10.5 CELE_F35G12.12 CELE_T07F10.5 CELE_T24A6.1 MCM7 cdc-6 cdk-2 cdt-1 cul-1 cya-1 let-358 lin-19 lin-6 mcm-2 mcm-3 mcm-4 mcm-5 mcm-6 mcm-7 orc-1 orc-2 orc-4 orc-5 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rbx-1 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 skpt-1 skr-1 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
RAC1 GTPase cycle	Amino acid transporter Amino acid transporter Arf-GAP domain-containing protein C2 DOCK-type domain-containing protein CED-5 CRAL-TRIO domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Chimerin 2 Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Excitatory amino acid transporter F-BAR domain-containing protein FYVE, RhoGEF and PH domain-containing protein tag-77 Formin-homology and zinc finger domains protein 1 GTPase-activating protein pac-1 Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor Guanine nucleotide-binding protein alpha-12 subunit MAGUK family Membrane-associated protein gex-3 Moesin/ezrin/radixin homolog 1 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Partitioning defective protein 6 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein ECT2 Protein let-99 Protein unc-112 Protein vav-1 Protein vav Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rac GTPase-activating protein 1 Ras-related protein Rab-7a Ras-related protein ced-10 Rho GTPase-activating protein 20 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH2 domain-containing protein SH3 domain-containing protein SH3 domain-containing protein START domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase mrck-1 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Son of sevenless homolog Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A0K3AR51 A0A2K5AU23 A0A4V0ILM7 A5PEW5 A5Z2X2 F0IWT2 G5EDP9 G5EDU3 G5EEN3 G5EEN8 G5EF62 G5EF80 G5EFE1 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 O01583 O01847 O02495 O17772 O17905 O18210 O44518 O45611 O61460 O61528 P03949 P34288 P34489 P46549 P46941 P55163 P91406 Q03206 Q05062 Q10901 Q10929 Q17850 Q18685 Q18879 Q19370 Q19467 Q19572 Q20440 Q20487 Q20496 Q21025 Q21341 Q21353 Q21430 Q21751 Q22682 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q94125 Q95XW5 Q965J0 Q965N4 Q9GYK2 Q9N5D3 Q9NAN2 Q9U364 Q9UAY8 Q9XUS9 Q9XVH4 Q9XVI0 Q9XVK6 Q9XW53 U4PAK0 X5LX76	C05D9.3 CELE_F22G12.5 CELE_F23H11.4 CELE_F46H5.4 CELE_T04C9.1 CELE_Y105E8A.25 CELE_Y57G11C.1147 PLD aap-1 abi-1 abl-1 aex-4 age-1 cav-1 cav-2 cdc-42 ced-10 ced-5 cgef-1 chin-1 citk-1 citk-2 cyk-1 cyk-4 ect-2 ephx-1 fozi-1 frm-3 gap gcp-2.1 gcp-2.2 gei-1 gex-2 gex-3 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 gpa-12 hum-7 kin-18 let-341 let-99 magu-1 max-2 mrck-1 pac-1 pak-1 pak-2 par-6 pes-7 pix-1 pkn-1 pld-1 rab-7 rac-1 rga-1 rga-2 rga-5 rga-8 rga-9 rhgf-1 rhi-1 ric-4 rlbp-1 snb-1 sos-1 spv-1 srgp-1 sulu syd-1 tag-325 tag-77 tag-81 tiam-1 toe-2 uig-1 unc-112 unc-73 vab-1 vang-1 vav-1 wve-1	Caenorhabditis elegans
MTOR signalling	14-3-3-like protein 1 14-3-3-like protein 2 DAF-15 GTP-binding protein Rheb homolog 1 GTP-binding protein Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Ragulator complex protein LAMTOR2 homolog Ras-related GTP-binding protein C Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Sodium-coupled neutral amino acid transporter 9 homolog Target of rapamycin complex subunit lst8 Target of rapamycin homolog	G5EGB3 O17268 P34443 P41932 P91040 Q17941 Q19425 Q20655 Q22743 Q68TI8 Q8WQG5 Q95Q95 Q9N2U6 Q9XTG7	CeTor F13H10.3 akt-1 akt-2 daf-15 ftt-1 ftt-2 let-363 lmtr-2 lmtr-3 lmtr-5 mlst-8 par-5 raga-1 ragc-1 rheb-1	Caenorhabditis elegans
LDL remodeling	Microsomal triglyceride transfer protein homolog Protein disulfide-isomerase 1 Protein disulfide-isomerase 2 Thioredoxin domain-containing protein	G5ECG7 H2FLL2 Q17770 Q17967	CELE_M04D5.1 dsc-4 pdi-1 pdi-2	Caenorhabditis elegans
Transport of vitamins, nucleosides, and related molecules	Acetyl-coenzyme A transporter 1	Q22816	CELE_T26C5.3	Caenorhabditis elegans
Neurotransmitter receptors and postsynaptic signal transmission	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor (51.1 kD) (Acr-22) Acetylcholine receptor subunit alpha-type acr-5 Acetylcholine receptor subunit alpha-type deg-3 Acetylcholine receptor subunit alpha-type des-2 Acetylcholine-gated chloride channel subunit acc-1 Acetylcholine-gated chloride channel subunit acc-2 Acetylcholine-gated chloride channel subunit acc-3 Acetylcholine-gated ion channel acc-4 Betaine receptor acr-23 Glutamate-gated ChLoride channel Glutamate-gated chloride channel alpha Glutamate-gated chloride channel subunit beta Glutamate-gated chloride channel subunit Glycine receptor subunit beta-type 4 Ig-like domain-containing protein Ig-like domain-containing protein Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-gated ion channel 4 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Neur_chan_LBD domain-containing protein Neur_chan_LBD domain-containing protein Neur_chan_memb domain-containing protein Neur_chan_memb domain-containing protein Neurotransmitter-gated ion-channel ligand binding domain protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Probable ligand-gated ion channel 46 Serotonin-gated chloride channel mod-1	A0A1N7SYW0 A0A3P6P985 A0A4V0IK40 A0A4V0IN81 B1Q281 G5EBR3 G5ECH3 G5EDN0 G5EE87 G5EEC1 G5EEX8 G5EEZ3 G5EG88 G5EGR1 H2KML8 H2KYN9 O17041 O17274 O17402 O18228 O44452 O61216 O61519 O61520 O76554 P41849 P54244 P54245 P54246 P90876 P91985 Q09453 Q10052 Q17328 Q18812 Q21005 Q21420 Q22588 Q22741 Q6BEQ0 Q95Q97 Q95QT7 Q95Y52 Q95Y94 Q9GQ00 Q9N517 Q9NA62 Q9U358 V6CJ96 X5LVB0	acc-1 acc-2 acc-3 acc-4 acr-20 acr-21 acr-22 acr-23 acr-24 acr-4 acr-5 avr-14 avr-15 deg-3 des-2 gbr-4 ggr-1 ggr-2 ggr-3 glc-1 glc-2 glc-3 glc-4 lgc-10 lgc-11 lgc-12 lgc-30 lgc-31 lgc-32 lgc-34 lgc-39 lgc-4 lgc-40 lgc-41 lgc-42 lgc-44 lgc-45 lgc-46 lgc-47 lgc-48 lgc-49 lgc-5 lgc-50 lgc-51 lgc-52 lgc-53 lgc-54 lgc-55 lgc-56 lgc-58 lgc-6 lgc-7 lgc-8 lgc-9 mod-1	Caenorhabditis elegans
ROS and RNS production in phagocytes	NRAMP-like transporter smf-1 NRAMP-like transporter smf-2 NRAMP-like transporter smf-3 Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q21433 Q21434 Q22494 Q23680 Q95X44 Q95XG8 Q95YD5 Q9N5A0 Q9XW92 Q9XXU9	fus-1 rdy-1 smf-1 smf-2 smf-3 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
Endosomal Sorting Complex Required For Transport (ESCRT)	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4b Charged multivesicular body protein 4b Charged multivesicular body protein 6 Charged multivesicular body protein 7 Hepatocyte growth factor-regulated tyrosine kinase substrate Multivesicular body subunit 12A Polyubiquitin-A Signal transducing adapter molecule 1 Tumor susceptibility gene 101 protein UBA domain-containing protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein VPS37 C-terminal domain-containing protein Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein-sorting-associated protein 25 Vacuolar protein-sorting-associated protein 36 Vacuolar-sorting protein SNF8	O01498 O02208 O44158 O76258 P0CG71 P37165 P49632 Q17687 Q17796 Q18258 Q18886 Q19519 Q21959 Q22718 Q8WTK0 Q9BL60 Q9GYK4 Q9NA26 Q9U2F6 Q9U354	C01A2.4 CELE_R12C12.5 chmp-7 hgrs-1 mvb-12 pqn-19 spe-48 stam-1 tsg-101 ubia ubib ubl-1 ubq-1 ubq-2 vps-2 vps-20 vps-22 vps-24 vps-25 vps-28 vps-32.1 vps-36 vps-37	Caenorhabditis elegans
GTP hydrolysis and joining of the 60S ribosomal subunit	60S ribosomal protein L29 Eukaryotic translation initiation factor 5B Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23B Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5B Large ribosomal subunit protein uL6 Plectin/S10 N-terminal domain-containing protein Ribosomal Protein, Small subunit Ribosomal protein L37 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS9 Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein	G4S0D4 G5EGT7 O01504 O01692 O01802 O01868 O01869 O02056 O02639 O17218 O17570 O18240 O18650 O44480 O45226 O45499 O45946 O62388 P34334 P34662 P37165 P46769 P47991 P48150 P48152 P48154 P48156 P48158 P48166 P49041 P49180 P49181 P49196 P49197 P49405 P50880 P51403 P51404 P52814 P52819 P52821 P61866 P90983 P91053 P91055 P91128 P91374 P91913 P91914 Q09533 Q19162 Q19869 Q19877 Q1XFY9 Q20206 Q20228 Q20647 Q21930 Q22054 Q22716 Q23312 Q27389 Q8WQA8 Q93572 Q95Y04 Q95Y90 Q966C6 Q9BKU5 Q9BL19 Q9N3X2 Q9N4I4 Q9NEN6 Q9TXP0 Q9U2A8 Q9U332 Q9XVE9 Q9XVF7 Q9XVP0 Q9XWS4	C16C8.14 C16C8.16 C16C8.20 C37A2.7 CELE_W01D2.1 CELE_Y37E3.8 iffb-1 rla-0 rla-1 rpa-0 rpa-1 rpl-1 rpl-10 rpl-10a rpl-11.2 rpl-12 rpl-13 rpl-14 rpl-15 rpl-16 rpl-17 rpl-18 rpl-19 rpl-2 rpl-20 rpl-21 rpl-22 rpl-23 rpl-24.1 rpl-25.2 rpl-26 rpl-27 rpl-28 rpl-29 rpl-3 rpl-30 rpl-31 rpl-32 rpl-33 rpl-35 rpl-36 rpl-36.A rpl-37a rpl-38 rpl-39 rpl-4 rpl-41 rpl-43 rpl-5 rpl-6 rpl-7 rpl-7A rpl-8 rpl-9 rps-0 rps-1 rps-10 rps-11 rps-12 rps-13 rps-14 rps-15 rps-16 rps-17 rps-18 rps-19 rps-2 rps-20 rps-21 rps-22 rps-23 rps-24 rps-25 rps-26 rps-27 rps-28 rps-29 rps-3 rps-4 rps-5 rps-6 rps-7 rps-8 rps-9 ubl-1	Caenorhabditis elegans
Phase 4 - resting membrane potential	IRK_C domain-containing protein Inward rectifier potassium channel irk-1 Inward rectifier potassium channel irk-1 Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein TWiK family of potassium channels protein 18 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Uncharacterized protein B0310.1	A0A1C3NSK2 A0A1C3NSN6 A1EHR5 F5GUD1 G5EBQ2 G5ECW6 G5EG92 G5EGD4 H2KZ66 O17185 O45422 O45891 O45894 P52192 Q10937 Q18120 Q21467 Q22042 Q22043 Q23297 Q65XY3 Q6BES3 Q6EUT8 Q9BL31 Q9NEV3 Q9XTV6 U4PFA8	B0310.1 irk-1 irk-2 irk-3 irk-4 sup-9 twk-1 twk-11 twk-14 twk-18 twk-20 twk-21 twk-22 twk-24 twk-25 twk-26 twk-31 twk-33 twk-34 twk-35 twk-36 twk-39 twk-42 twk-44 twk-45 twk-46 twk-49 twk-8	Caenorhabditis elegans
Integrin cell surface interactions	Collagen alpha-1(IV) chain Collagen alpha-2(IV) chain Contactin rig-6 Discoidin domain-containing receptor tyrosine kinase B Fibronectin type-III domain-containing protein Ig-like domain-containing protein Integrin alpha ina-1 Integrin alpha pat-2 Integrin beta pat-3 Protein kinase domain-containing protein Protein kinase domain-containing protein Titin homolog Uncharacterized integrin beta-like protein C05D9.3	A0A1I6CMA1 C6KRM7 G4SLH0 H2KZ60 P17139 P17140 P34446 Q03600 Q18096 Q21046 Q27874 Q95ZV7 Q9GYK2	C05D9.3 C18E9.7 CELE_F59F5.3 clb-1 clb-2 ddr-2 emb-9 ina-1 kin-36 let-2 pat-2 pat-3 rig-5 rig-6 svh-4 ttn-1	Caenorhabditis elegans
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Two pore potassium channel protein sup-9	Q9NEV3	twk-46	Caenorhabditis elegans
Linoleic acid (LA) metabolism	ABC transporter domain-containing protein Delta(5) fatty acid desaturase fat-4 Delta(6)-fatty-acid desaturase fat-3 Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Long chain fatty acid elongase 1 Long chain fatty acid elongase 2 Long chain fatty acid elongase 5 Long chain fatty acid elongase 6 Putative fatty acid elongase 3 Putative fatty acid elongase 4	F3Y5R4 G5EEE5 G5EG11 O45730 P49191 Q03574 Q20300 Q20303 Q20904 Q23221 Q9NAC6 Q9XVQ9	des-5 elo-1 elo-2 elo-3 elo-4 elo-5 elo-6 elo-7 elo-8 elo-9 fat-3 fat-4 pmp-4	Caenorhabditis elegans
Ciprofloxacin ADME	ABC transporter domain-containing protein ABC transporter family G domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Organic cation transporter 1 Putative transporter B0252.3 Putative transporter B0361.11 Solute carrier organic anion transporter family member Uncharacterized protein F23F12.3	A0A0K3AVV4 A0A0K3AWD3 A0A238UKL7 D7SFK1 G5EDA7 G5EEI9 G5EGL6 O18247 P46499 Q09617 Q10917 Q18613 Q18655 Q18795 Q19442 Q19585 Q22686 Q23501 Q4PIX1 Q7Z118 Q93550 Q9BKR9 Q9U539 Q9UAW9	B0252.3 B0361.11 C06H5.6 C44C10.3 C46C2.2 CELE_F21G4.1 CELE_F23F12.13 CELE_F45E10.2 CELE_K05F1.6 CELE_K09E9.1 CELE_K11D9.3 CELE_T08B1.1 CELE_T12B3.2 CELE_T22F7.1 CELE_Y57G11C.23 CELE_Y82E9BR.16 CELE_ZK892.3 F23F12.3/F23F12.1 abcx-1 oct-1 oct-2 pes-23 suex-2 wht-5	Caenorhabditis elegans
Amine ligand-binding receptors	G-protein coupled receptors family 1 profile domain-containing protein	Q17553	npr-42	Caenorhabditis elegans
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3 EF-hand domain-containing protein Inositol polyphosphate-related phosphatase domain-containing protein Inositol-trisphosphate 3-kinase homolog PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 Phosphoinositide phospholipase C Probable phospholipase D F09G2.8 Rho-GAP domain-containing protein Synaptojanin	G5EBH0 G5ECL2 G5EE01 G5EFI8 G5EGN9 H2KZ05 O17405 O17590 Q18136 Q19056 Q21754 Q22070 Q8I4C7 Q95Q62	CELE_E04F6.4 CELE_T05C3.6 CELE_Y51A2D.13 F09G2.8 cal-5 daf-18 egl-8 inpp-1 lfe-2 ocrl-1 plc-1 plc-3 plc-4 unc-26	Caenorhabditis elegans
IRE1alpha activates chaperones	Serine/threonine-protein kinase/endoribonuclease ire-1	Q09499	ire-1	Caenorhabditis elegans
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	14-3-3-like protein 1 14-3-3-like protein 2 Cyclin N-terminal domain-containing protein Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B	O45926 P34556 P41932 Q10653 Q20655 Q9BLB5	cdk-1 cyb-1 cyb-2.1 cyb-2.2 ftt-1 ftt-2 ncc-1 par-5	Caenorhabditis elegans
RHOQ GTPase cycle	ADP-ribosylation factor-like protein 13B Amino acid transporter Amino acid transporter Anion exchange protein Arf-GAP domain-containing protein Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cdc-42 Related Protein Cell division control protein 42 homolog E3 ubiquitin-protein ligase wwp-1 Excitatory amino acid transporter Glutamate carboxypeptidase 2 homolog Intersectin-1 MAGUK family Multidrug resistance-associated protein lethal(2)03659 N-acetylated-alpha-linked acidic dipeptidase 2 Nicotinic receptor-associated protein 1 PDZ domain-containing protein Protein lap1 Protein let-99 Protein vav Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Ras-related protein Rab-7a Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH3 domain-containing protein START domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase mrck-1 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Stomatin-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Transducer of Cdc42-dependent actin assembly protein 1 homolog Transducer of Cdc42-dependent actin assembly protein 2 homolog Vang-like protein WAPL domain-containing protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase t-SNARE protein aex-4	A0A0K3AS36 A0A2K5AU23 A5PEW5 B3WFV9 G5EEN8 G5EF62 G5EFU0 G5EGQ3 H2KY90 H2KZH5 H2KZV6 H2L0N8 O01583 O02495 O17772 O18210 O18302 O44326 O45611 O61967 O62422 P91406 Q05062 Q10901 Q10953 Q17850 Q18825 Q18879 Q19253 Q19370 Q19467 Q19625 Q19958 Q20440 Q21025 Q21341 Q21353 Q21430 Q21751 Q22682 Q23130 Q23146 Q7JP75 Q86NH1 Q93332 Q94051 Q95XW5 Q9N2Z7 Q9UAY8 Q9XUB9 Q9XUS7 Q9XVH4	CELE_T04C9.1 abts-1 aex-4 arl-13 bar-1 cav-1 cav-2 cdc-42 citk-1 citk-2 crp-1 cyk-1 gcp-2.1 gcp-2.2 gei-1 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 gopc-1 hmp-2 itsn-1 let-413 let-99 magu-1 max-2 mrck-1 mrp-6 nra-1 pak-1 pak-2 pes-7 pix-1 pvl-1 rab-7 rga-1 rga-5 rga-8 ric-4 snb-1 spy-1 srgp-1 sto-2 syd-1 tag-81 toca-1 toca-2 toe-2 uig-1 vang-1 wrm-1 wwp-1	Caenorhabditis elegans
EPH-Ephrin signaling	Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin receptor 1 Ephrin-4	G5EEE7 O44516 O61460 Q19475 Q9U3M2	efn-2 efn-3 efn-4 mab-26 vab-1 vab-2	Caenorhabditis elegans
Fatty acyl-CoA biosynthesis	ATPase morc-1 Acetyl-CoA carboxylase Delta(9)-fatty-acid desaturase fat-5 Delta(9)-fatty-acid desaturase fat-6 Delta(9)-fatty-acid desaturase fat-7 Fatty acid synthase Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Palmitoyl-protein thioesterase 1 Probable ATP-citrate synthase	G5ED44 G5EGH6 G5EGN2 H2L0M0 P53585 P91871 Q18916 Q19878 Q20390 Q23243	acly-1 acs-20 acs-22 fasn-1 fat-5 fat-6 fat-7 morc-1 pod-2 ppt-1	Caenorhabditis elegans
Signal transduction by L1	Casein kinase II subunit alpha Casein kinase II subunit beta Dual specificity mitogen-activated protein kinase kinase mek-2 Ig-like domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Protein vav-1 Ras-related protein ced-10 Receptor tyrosine-protein kinase let-23 Serine/threonine-protein kinase pak-1 Uncharacterized integrin beta-like protein C05D9.3	P18334 P24348 P28548 P34446 P39745 Q03206 Q10656 Q10664 Q17850 Q27874 Q45FX5 Q5WRR1 Q9GYK2	C05D9.3 ced-10 egl-15 kin-10 kin-3 kin-5 kin-7 let-23 mek-2 mpk-1 pak-1 pat-2 pat-3 rac-1 sur-1 vav-1 wrk-1	Caenorhabditis elegans
Formation of the Early Elongation Complex	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIF subunit 2 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase Rpb4/RPC9 core domain-containing protein Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha	G5EFV5 K8F7X5 O01763 O02092 O17245 O44499 P16356 P34567 Q09645 Q10578 Q17558 Q17684 Q19826 Q21338 Q8MYM8 Q93338 Q93594 Q95PZ4 Q95QG8 Q965S0 Q9GR61 Q9N390 Q9N3C9 Q9N3L2 Q9N5K2 Q9TZ93 Q9U3I0 Q9XVH6	ama-1 cbp-20 cbp-80 cdk-7 fcp-1 gtf-2F1 gtf-2F2 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2f1 gtf-2f2 gtf-2h1 gtf-2h3 mnat-1 ncbp-1 ncbp-2 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 spt-4 spt-5 xpb-1 xpd-1	Caenorhabditis elegans
Gastrin-CREB signalling pathway via PKC and MAPK	Mitogen-activated protein kinase mpk-1 Mitogen-activated protein kinase Putative ribosomal protein S6 kinase alpha-1	H2KYF8 P39745 Q21734	mpk-1 mpk-2 rskn-1 sur-1	Caenorhabditis elegans
G alpha (z) signalling events	G protein gamma domain-containing protein Guanine nucleotide-binding protein alpha-5 subunit Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma RGS domain-containing protein RGS domain-containing protein Regulator of G-protein signaling rgs-10 Regulator of G-protein signaling rgs-11 Regulator of G-protein signaling rgs-1 Regulator of G-protein signaling rgs-2 Regulator of G-protein signaling rgs-3 Regulator of G-protein signaling rgs-6 Regulator of G-protein signaling rgs-7 Regulator of G-protein signaling rgs-9 Tyramine receptor Ser-2 Tyramine receptor tyra-2 adenylate cyclase adenylate cyclase adenylate cyclase adenylate cyclase	A0A5S9MNH1 G5ECK9 G5ECT6 G5EE33 O02213 O16880 O45523 O45524 P17343 P34295 P49808 P54406 Q18312 Q18563 Q19084 Q19523 Q20636 Q20701 Q23376 Q8WQC0 Q966F9	acy-1 acy-2 acy-3 acy-4 eat-11 gbp-2 gpa-5 gpb-1 gpb-2 gpc-1 gpc-2 rgs-1 rgs-10 rgs-11 rgs-2 rgs-3 rgs-4 rgs-6 rgs-7 rgs-8.1 rgs-8.2 rgs-9 ser-2 tyra-2	Caenorhabditis elegans

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