GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
HSP90 chaperone cycle for SHRs	DNaJ domain (Prokaryotic heat shock protein) DNaJ domain (Prokaryotic heat shock protein) DUF148 domain-containing protein Heat shock protein 90 Heat shock protein hsp-1 Stress-induced-phosphoprotein 1	G5EC99 O16259 O16303 O45502 P09446 Q18688	CELE_F11F1.1 daf-21 dnj-12 dnj-19 hsp-1 hsp70a sti-1	Caenorhabditis elegans
alpha-linolenic acid (ALA) metabolism	ABC transporter domain-containing protein Acyl-coenzyme A oxidase acox-1.3 Delta(5) fatty acid desaturase fat-4 Delta(6)-fatty-acid desaturase fat-3 Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Long chain fatty acid elongase 1 Long chain fatty acid elongase 2 Long chain fatty acid elongase 5 Long chain fatty acid elongase 6 MaoC-like domain-containing protein Putative fatty acid elongase 3 Putative fatty acid elongase 4 palmitoyl-CoA hydrolase	F3Y5R4 G5EEE5 G5EG11 O45730 O62138 P49191 Q03574 Q19058 Q20300 Q20303 Q20904 Q23221 Q9BIA9 Q9NAC6 Q9XVQ9	C17C3.1 acox-1.3 acox-3 des-5 elo-1 elo-2 elo-3 elo-4 elo-5 elo-6 elo-7 elo-8 elo-9 fat-3 fat-4 maoc-1 pmp-4	Caenorhabditis elegans
Retinoid metabolism and transport	Beta,beta-carotene 9',10'-oxygenase Beta,beta-carotene 9',10'-oxygenase Carotenoid oxygenase Fatty acid-binding protein homolog 5 Fatty acid-binding protein homolog 6 Fatty acid-binding protein homolog 7 Fatty acid-binding protein homolog 8 LiPocalin-Related protein Lipase_GDSL domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Probable 5-hydroxyisourate hydrolase R09H10.3 Probable 5-hydroxyisourate hydrolase ZK697.8	G5EEB8 H2L060 O01812 O01814 O02323 O02324 O44578 P91020 P91997 P91998 Q17568 Q18903 Q21274 Q21882 Q22352 Q23320 Q9N2Z4 Q9NAI5 Q9TXT9 Q9U2E4 Q9U2J5	C01G5.5 C07D8.6 C56G3.2 CELE_F49E10.2 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_Y65B4BR.1 CELE_ZC443.1 R09H10.3 ZK697.8 bcmo-1 bcmo-2 exc-15 lbp-5 lbp-6 lbp-7 lbp-8 lpr-2	Caenorhabditis elegans
HS-GAG biosynthesis	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 GlyPicaN Heparan sulfate 2-O-sulfotransferase hst-2 Heparan-sulfate 6-O-sulfotransferase Ig-like domain-containing protein InTestinal NeureXin-like LONg Laminin G domain-containing protein Probable syndecan Sulfotransferase domain-containing protein Sulfotransferase domain-containing protein Thioredoxin domain-containing protein Titin homolog UDP-sugar transporter sqv-7	C6KRM7 G4SLH0 G5ECV3 G5EFN7 G5EGU4 O17645 O45000 P50605 Q18530 Q18779 Q22574 Q4TTA0 Q966W3 Q9TZK5	C03H12.1 CELE_T19D12.6 gpn-1 hst-1 hst-2 hst-3.1 hst-3.2 hst-6 itx-1 lon-2 rig-5 sdn-1 sqv-7 ttn-1	Caenorhabditis elegans
VEGFR2 mediated cell proliferation	Protein kinase C-like 1 Protein kinase C-like 2 Protein kinase C-like 3 Sphingosine kinase 1 non-specific serine/threonine protein kinase	P34722 P90980 Q18425 Q19266 Q9UA62	CELE_W04B5.5 aPKC kin-11 pkc-2 pkc-3 sphk-1 tag-274 tpa-1	Caenorhabditis elegans
Synthesis of bile acids and bile salts	Cholesterol 25-hydroxylase-like protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein	A7DTF2 O01686 Q20027 Q93485	F35C8.5 obr-1 obr-2 obr-4	Caenorhabditis elegans
Downregulation of ERBB2 signaling	Cullin-5 E3 ubiquitin-protein ligase CHIP EGF-like domain-containing protein EGF-like domain-containing protein Heat shock protein 90 Polyubiquitin-A Probable Hsp90 co-chaperone cdc37 Protein kinase domain-containing protein Protein roller-3 Receptor tyrosine-protein kinase let-23 Tyrosine-protein kinase csk-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	G5ECJ6 G5ECY6 G5EFK8 O02108 O44191 P0CG71 P24348 P37165 P49632 Q18688 Q23639 Q8I7I5 Q9XX42	1G758 CELE_F14B4.1 CELE_Y38H6C.20 cdc-37 chn-1 csk-1 cul-5 daf-21 kin-7 let-23 rme-2 rol-3 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Glycerophospholipid catabolism	GP-PDE domain-containing protein Patatin-like phospholipase domain-containing protein ZK370.4 Putative patatin-like phospholipase domain-containing protein M110.7 glycerophosphocholine cholinephosphodiesterase	Q02331 Q21534 Q22129 Q9UAW8	CELE_T03G6.3 CELE_T12B3.3 M110.7 ZK370.4	Caenorhabditis elegans
Transport of RCbl within the body	Multidrug resistance-associated protein 1	Q3S1M2	mrp-1	Caenorhabditis elegans
Calmodulin induced events	EF-hand domain-containing protein G protein-coupled receptor kinase 2 Protein kinase C-like 1 Protein kinase C-like 2	P34722 P90980 Q09639 Q18136	cal-5 grk-2 kin-11 pkc-2 tpa-1	Caenorhabditis elegans
Ubiquitin-dependent degradation of Cyclin D	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 G1/S-specific cyclin-D MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P37165 P46502 P49632 P90868 P91477 Q04908 Q10920 Q17971 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q27488 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9U2M5 Q9XTT9 Q9XUV0	C14C10.5 CELE_F35G12.12 cyd-1 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
TGF-beta receptor signaling activates SMADs	BMP-like protein unc-129 Cell surface receptor daf-1 Cell surface receptor daf-4 Dauer larva development regulatory growth factor daf-7 Dwarfin sma-4 E3 ubiquitin-protein ligase CBL FYVE-type domain-containing protein Furin-like protease kpc-1 Integrin alpha pat-2 Integrin beta pat-3 Nidogen Protein dbl-1 Smad protein daf-8 Uncharacterized integrin beta-like protein C05D9.3 peptidylprolyl isomerase peptidylprolyl isomerase	G5EBY8 G5EEL5 H2KZI9 O17798 P20792 P34446 P45897 P50488 P92172 Q19019 Q21733 Q27874 Q8I4E5 Q93791 Q9GYK2 Q9U2Q8	C05D9.3 aka-1 cem-3 cet-1 daf-1 daf-4 daf-7 daf-8 dbl-1 fkb-2 fkb-8 kpc-1 nid-1 pat-2 pat-3 sli-1 sma-4 unc-129	Caenorhabditis elegans
ERBB2 Activates PTK6 Signaling	EGF-like domain-containing protein EGF-like domain-containing protein Protein kinase domain-containing protein Protein nipi-4 Receptor tyrosine-protein kinase let-23 Tyrosine-protein kinase	A0A4V0IL59 G5EFK8 O16262 O44191 P24348 Q9N3S5	CELE_F14B4.1 CELE_Y47G6A.5 kin-7 let-23 nipi-4 rme-2 trk-1	Caenorhabditis elegans
Nephrin family interactions	Calponin-homology (CH) domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family SH2 domain-containing protein Synaptogenesis protein syg-1 Synaptogenesis protein syg-2 Tyrosine protein-kinase src-1	B1Q236 G5EE56 O17772 Q95PX0 Q95XA9 Q9U3P2	gap-3 nck-1 pes-7 src-1 syg-1 syg-2	Caenorhabditis elegans
Ca2+ pathway	Abnormal cell lineage protein 44 Beta-catenin-like protein hmp-2 Calcium/calmodulin-dependent protein kinase type II EF-hand domain-containing protein Frizzled-2 Frizzled-4 G protein gamma domain-containing protein Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma Protein Wnt-2 Protein mom-2 Protein mom-5 Protein phosphatase 2B regulatory subunit cnb-1 Protein pop-1 Ras protein let-60 Serine/threonine kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit	A0A0K3AWM6 G5ECQ2 G5ECT6 G5EDN6 G5EDV1 O44326 O62305 P17343 P22981 P34889 P51875 P54406 Q0G819 Q10459 Q10666 Q18136 Q20636 Q27886 Q9U9Y8	cal-5 cfz-2 cna-1 cnb-1 cwn-2 eat-11 gbp-2 goa-1 gpb-1 gpb-2 gpc-1 gpc-2 hmp-2 let-60 lin-17 lin-34 lin-44 lit-1 mom-2 mom-5 nlk pop-1 tax-6 unc-43 wnt-2	Caenorhabditis elegans
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase A EF-hand domain-containing protein Hyaluronidase Na(+)/H(+) exchanger protein 7	G5EBK1 G5ECE8 Q22492 Q23643 Q95Q32	CELE_Y105E8B.9 Chnase chhy-1 chpf-1 hex-1 nhx-7 pbo-4	Caenorhabditis elegans	G35674CY
Scavenging of heme from plasma	MMP-like protein Matrix metalloproteinase-A Matrix metalloproteinase-B Matrix metalloproteinase-C Peptidase metallopeptidase domain-containing protein Uncharacterized protein	G5EBU3 G5ECC4 G5EGM1 O17913 O44836 Q21182	CELE_K03B8.6 zmp-1 zmp-2 zmp-3 zmp-5 zmp-6	Caenorhabditis elegans
Glyoxylate metabolism and glycine degradation	Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase D-amino-acid oxidase D-aspartate oxidase 1 D-aspartate oxidase 2 D-aspartate oxidase 3 FMN hydroxy acid dehydrogenase domain-containing protein Proline dehydrogenase 1, mitochondrial	B1GRK5 O01739 O02158 O45228 O45307 Q17994 Q19564 Q94055 Q95XG9	CELE_F41E6.5 CELE_T09B4.8 agxt-1 daao-1 ddo-1 ddo-2 ddo-3 got-2.2 prdh-1 prodh	Caenorhabditis elegans
Thyroxine biosynthesis	Dual oxidase 1 Iodotyrosine dehalogenase 1 homolog NAD(P)H oxidase (H2O2-forming) Peroxidasin homolog pxn-1 Peroxidasin homolog pxn-2 Sodium-coupled monocarboxylate transporter 2 Sodium-dependent multivitamin transporter	G5EG78 O01795 O17394 O61213 P34273 Q1ENI8 Q23616	CELE_F52H2.4 bli-3 duox-2 pxn-1 pxn-2 slc-5A12 sup-18	Caenorhabditis elegans
Glutamate Neurotransmitter Release Cycle	Acetylcholine regulator unc-18 Amino acid transporter Amino acid transporter Excitatory amino acid transporter Liprin-alpha Major facilitator superfamily (MFS) profile domain-containing protein PRA1 family protein Phorbol ester/diacylglycerol-binding protein unc-13 Potential vesicular glutamate transporter vglu-3 Probable vesicular glutamate transporter eat-4 Putative complexin-1 Putative glutaminase 2 Putative glutaminase 3 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rab-3-interacting molecule unc-10 Ras-related protein Rab-3 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Synaptotagmin-1 Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Variant SH3 domain protein glutaminase t-SNARE protein aex-4	A5PEW5 G5EBK2 G5EEK1 G5EEN8 H2KZJ7 O02495 O16000 O18210 P27715 P34351 P34644 P34693 P34815 Q10046 Q10901 Q19013 Q19767 Q21049 Q21353 Q21751 Q22366 Q22682 Q93650 Q94057 Q94986 Q95XH1 Q9GUM7 Q9N415 Q9UAY8 U4PRW7	aex-4 cpx-1 eat-4 glna-1 glna-2 glna-3 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 lan-2 praf-3 rab-3 ric-4 rimb-1 snb-1 snb-2 snb-5 snb-6 snb-7 snt-1 syd-2 tag-168 tag-81 unc-10 unc-13 unc-18 unc-64 vamp-7 vglu-2 vglu-3	Caenorhabditis elegans
Cargo recognition for clathrin-mediated endocytosis	AP complex subunit beta AP complex subunit sigma AP-2 complex subunit alpha AP-2 complex subunit mu Beta-arrestin arr-1 C2 domain-containing protein C2 domain-containing protein C2 domain-containing protein C2 domain-containing protein COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 Clathrin light chain DiSHevelled related DiSHevelled related E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein EGF-like domain-containing protein EHS-1 ENTH domain-containing protein Endophilin-A homolog FCH domain only protein 2 Frizzled-4 G-protein coupled receptors family 1 profile domain-containing protein Hepatocyte growth factor-regulated tyrosine kinase substrate Intersectin-1 Multidrug resistance-associated protein lethal(2)03659 Muscarinic acetylcholine receptor gar-3 NECAP PHear domain-containing protein NEDD8 Phosphatidylinositol-binding clathrin assembly protein unc-11 Polyubiquitin-A Probable G-protein coupled receptor tkr-1 Probable clathrin heavy chain 1 Protein Wnt-2 Putative stoned B-like protein Receptor tyrosine-protein kinase let-23 SH3 domain-containing protein Segment polarity protein dishevelled homolog mig-5 Sensory neuron membrane protein 2 Sex muscle abnormal protein 5 Signal transducing adapter molecule 1 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptotagmin 2 Synaptotagmin-1 Torsin-like protein Torsin Torsin UBA domain-containing protein Ubiquilin Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Vesicular acetylcholine transporter unc-17	A0A0K3AS36 A0A0K3AUI8 B1V8A0 G5EBK2 G5EDV1 G5EFF7 G5EFK8 K8FE10 O01422 O01498 O02495 O16700 O18014 O44191 O45271 P0CG71 P24348 P29355 P34351 P34574 P34693 P34711 P34889 P35603 P37165 P49632 P51485 P90761 P90879 P90961 P91001 P91493 Q03566 Q17796 Q18239 Q19019 Q19123 Q19136 Q19625 Q19767 Q22227 Q22601 Q23056 Q6A573 Q93725 Q94057 Q95NU5 Q95PZ0 Q95XH1 Q9BI71 Q9BIF4 Q9GS00 Q9N359 Q9N425 Q9N489 Q9N4F3 Q9TXS0 Q9U7D5 Q9XTT3 Q9XXG5 Q9XZI6	CELE_F14B4.1 CELE_F49C12.9 CELE_T27E4.1 ap50 apa-2 apb-1 aps-2 apt-10 arr-1 cdap-2 chc-1 clic-1 csn-1 csn-2 csn-3 csn-4 csn-5 csn-6 cwn-2 dpy-23 dsh-1 dsh-2 ehs-1 epn-1 fcho-1 gar-3 hgrs-1 itsn-1 kin-7 let-23 lin-17 mig-5 mrp-6 ncap-1 ned-8 npr-25 ooc-5 pqn-19 rme-2 scav-3 sem-5 sli-1 snb-1 snb-2 snb-5 snb-6 snb-7 snt-1 snt-2 snt-4 snt-5 stam-1 sue-1 tkr-1 tor-1 tor-2 ubia ubib ubl-1 ubq-1 ubq-2 ubql-1 unc-11 unc-17 unc-41 unc-57 vamp-7 wnt-2	Caenorhabditis elegans
trans-Golgi Network Vesicle Budding	ADP-ribosylation factor 1-like 1 ADP-ribosylation factor 1-like 2 E3 ubiquitin-protein ligase arc-1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 homolog Putative syntaxin-2 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein t-SNARE protein aex-4	A5PEW5 G5EBK2 G5EEN8 G5EGS5 O02495 O16000 P34351 Q09654 Q10943 Q19767 Q20574 Q94057 Q94231 Q95XH1	aex-4 arc-1 arf-1 arf-1.1 arf-1.2 arl-4 arl-6 gbf-1 phi-34 ric-4 snb-1 snb-2 snb-5 snb-6 snb-7 syn-2 syx-2 tag-81 unc-64 vamp-7	Caenorhabditis elegans
RET signaling	GDNF/GAS1 domain-containing protein Protein kinase domain-containing protein	A0A2C9C3B4 Q95XG5	CELE_F09G2.1 CELE_Y69A2AR.31	Caenorhabditis elegans
Hyaluronan biosynthesis and export	Multidrug resistance-associated protein 5	G5EE72	mrp-5	Caenorhabditis elegans	G35674CY
Erythrocytes take up carbon dioxide and release oxygen	Ammonium transporter AmtB-like domain-containing protein Anion exchange protein Carbonic anhydrase Putative carbonic anhydrase 3 Putative carbonic anhydrase 5	O02637 Q10462 Q22947 Q27504 Q58QG8	abts-4 cah-3 cah-5 cah-6 rhr-1	Caenorhabditis elegans

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