GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Ion influx/efflux at host-pathogen interface	NRAMP-like transporter smf-1 NRAMP-like transporter smf-2 NRAMP-like transporter smf-3	Q21433 Q21434 Q95XG8	smf-1 smf-2 smf-3	Caenorhabditis elegans
Protein methylation	Electron transfer flavoprotein beta subunit lysine methyltransferase homolog Electron transfer flavoprotein subunit beta Elongation factor 1-alpha Protein-lysine N-methyltransferase CELE_F29B9.1 Protein-lysine N-methyltransferase M142.8 Protein-lysine methyltransferase C42C1.13 Transitional endoplasmic reticulum ATPase homolog 2	A7IQW5 O01503 P53013 P54812 Q5WRN3 Q9GYH9 Q9TXI4	C37A2.6 C42C1.13 CELE_F23C8.5 CELE_F29B9.1 M142.8 cdc-48.2 eft-3 eft-4	Caenorhabditis elegans
Disassembly of the destruction complex and recruitment of AXIN to the membrane	Axin-like protein pry-1 Caveolin-1 Caveolin-2 DiSHevelled related DiSHevelled related EGF-like domain-containing protein EGF-like domain-containing protein Frizzled-2 Glycogen synthase kinase-3 Protein kinase domain-containing protein Protein mom-5 Putative serine/threonine-protein kinase R03D7.5 Segment polarity protein dishevelled homolog mig-5	A0A0K3AUI8 A0A0K3AWM6 G5ECQ2 G5EFK8 O44191 O62090 Q09595 Q18239 Q18879 Q22227 Q93372 Q94051 Q9U2Q9	C44H4.6 CELE_F14B4.1 R03D7.5 cav-1 cav-2 cfz-2 dsh-1 dsh-2 gsk-3 mig-5 mom-5 pry-1 rme-2 sgg-1	Caenorhabditis elegans
Cellular hexose transport	EGL-17 Facilitated glucose transporter homolog Facilitated glucose transporter protein 1 MFS domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein	G5EC93 G5EEF1 O16547 O44616 O44827 O45920 Q19376 Q20734 Q21381 Q21382 Q21385 Q23535 Q23626 Q5WRR9 Q95QY6 Q9GPA2 Q9GYQ1 Q9N309 Q9NEI8 Q9U2K5 Q9XU83 Q9XVL3	C03B1.13 C35A11.4 CELE_F11D5.5 CELE_F11D5.7 CELE_F13B12.2 CELE_F48E3.2 CELE_F53H8.3 CELE_K08F9.1 CELE_K08H10.6 CELE_K09C4.1 CELE_K09C4.4 CELE_K09C4.5 CELE_Y37A1A.3 CELE_Y39B6A.41 CELE_Y39E4B.5 CELE_Y61A9LA.1 CELE_ZK829.9 R09B5.11 egl-17 fdgt-2 fgt-1 slcf-2	Caenorhabditis elegans	G58161NS
Iron uptake and transport	ABC transporter domain-containing protein ABC transporter family G domain-containing protein Cullin-1 Cullin-associated NEDD8-dissociated protein 1 Cytochrome b561 domain-containing protein Cytochrome b561 domain-containing protein Cytoplasmic aconitate hydratase Ferritin Ferritin NEDD8 NRAMP-like transporter smf-1 Polyubiquitin-A Proton-coupled folate transporter Putative transmembrane ascorbate-dependent reductase CYB561 homolog Skp1-related protein SoLute Carrier family Related SoLute Carrier family Related Solute carrier family 46 member 3 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized MFS-type transporter C09D4.1	D7SFK1 G5ECU1 G5ED41 H2KZC0 O01735 O16271 O16272 O16453 P0CG71 P34465 P37165 P49632 Q17389 Q19585 Q20236 Q21434 Q23500 Q93725 Q9TYS3 Q9UAZ6 Q9XWL3	C09D4.1 CELE_F39G3.4 CELE_F39G3.5 F55H2.5 abcx-1 aco-1 cand-1 cul-1 ftn-1 ftn-2 gei-22 lin-19 ned-8 skr-1 slc-46A slc-46a slcr-46.1 slcr-46.2 slcr-46.3 smf-1 ubia ubib ubl-1 ubq-1 ubq-2 wht-5	Caenorhabditis elegans
Adrenoceptors	G-protein coupled receptors family 1 profile domain-containing protein Tyramine receptor Ser-2 Tyramine receptor tyra-2	G5EBX8 O02213 Q19084	ser-2 ser-5 tyra-2	Caenorhabditis elegans
mTORC1-mediated signalling	14-3-3-like protein 1 14-3-3-like protein 2 DAF-15 Eukaryotic elongation factor 2 kinase GTP-binding protein Rheb homolog 1 GTP-binding protein Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 MIF4G domain-containing protein Ragulator complex protein LAMTOR2 homolog Ras-related GTP-binding protein C Ribosomal protein S6 kinase beta Small ribosomal subunit protein eS6 Sodium-coupled neutral amino acid transporter 9 homolog Target of rapamycin complex subunit lst8 Target of rapamycin homolog peptidylprolyl isomerase peptidylprolyl isomerase	A0A486WX07 G5EGB3 O01991 O17268 P34443 P41932 P91040 Q19425 Q20655 Q22743 Q68TI8 Q8I4E5 Q8WQG5 Q95Q95 Q9N2U6 Q9NAH6 Q9NEN6 Q9U2Q8	CeTor F13H10.3 daf-15 efk-1 fkb-2 fkb-8 ftt-1 ftt-2 ifg-1 let-363 lmtr-2 lmtr-3 lmtr-5 mlst-8 par-5 raga-1 ragc-1 rheb-1 rps-6 rsks-1	Caenorhabditis elegans
EGFR downregulation	Cell division control protein 42 homolog E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein EGF-like domain-containing protein EHS-1 ENTH domain-containing protein Endophilin-A homolog Hepatocyte growth factor-regulated tyrosine kinase substrate Polyubiquitin-A Receptor tyrosine-protein kinase let-23 SH3 domain-containing protein SH3 domain-containing protein Sex muscle abnormal protein 5 Signal transducing adapter molecule 1 Tyrosine-protein phosphatase 1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	B1V8A0 G5EFK8 O01498 O44191 P0CG71 P24348 P28191 P29355 P37165 P49632 Q05062 Q17796 Q19019 Q21430 Q6A573 Q9BI71 Q9BIF4	CELE_F14B4.1 cdap-2 cdc-42 ehs-1 epn-1 hgrs-1 kin-7 let-23 pix-1 pqn-19 ptp-1 rme-2 sem-5 sli-1 stam-1 ubia ubib ubl-1 ubq-1 ubq-2 unc-57	Caenorhabditis elegans
RUNX3 regulates p14-ARF	BMP-like protein unc-129 Core-binding factor subunit beta homolog bro-1 Dauer larva development regulatory growth factor daf-7 G1/S-specific cyclin-D Histone deacetylase 4 Protein cbp-1 Protein dbl-1 Runt-related transcription factor rnt-1	G5EBY8 G5EEL5 G5EFQ5 O17323 P34545 P92172 Q95ZL9 Q9U2M5	bro-1 cbp-1 cet-1 cyd-1 daf-7 dbl-1 hda-4 hda-7 mab-2 rnt-1 run-1 unc-129	Caenorhabditis elegans
Fibronectin matrix formation	Fibronectin type-III domain-containing protein Integrin alpha pat-2 Uncharacterized integrin beta-like protein C05D9.3	P34446 Q18096 Q9GYK2	C05D9.3 C18E9.7 pat-2	Caenorhabditis elegans
Cyclin E associated events during G1/S transition	Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor G1/S-specific cyclin-E M-phase inducer phosphatase cdc-25.1 M-phase inducer phosphatase cdc-25.2 M-phase inducer phosphatase cdc-25.3 M-phase inducer phosphatase Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2	G5EEJ2 O01501 O44552 O44628 O61847 P30634 Q17941 Q21762 Q9XTG7	akt-1 akt-2 cdc-25.1 cdc-25.2 cdc-25.3 cdc-25.4 cdk-2 cki-2 cye-1	Caenorhabditis elegans
Regulation of TLR by endogenous ligand	BPI1 domain-containing protein BPI2 domain-containing protein BPI2 domain-containing protein BPI2 domain-containing protein High mobility group protein 1.2 Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Nose resistant to fluoxetine protein 5 Uncharacterized protein T19C3.5	A8WFJ7 H9G2Z8 O17768 Q09390 Q10011 Q17654 Q17738 Q18869 Q20380 Q23365 Q93796	C05C9.1 C06E8.5 C06G1.1 C55C3.1 CELE_F01G10.10 CELE_F10D11.6 CELE_F44A2.3 CELE_ZC513.2 T19C3.5 hmg-1.2 nrf-5	Caenorhabditis elegans
Glycerophospholipid biosynthesis	Uncharacterized protein F52C9.3	Q10123	F52C9.3	Caenorhabditis elegans
Insulin receptor recycling	Insulin-like receptor Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit S1 V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q22494 Q23680 Q95X44 Q95YD5 Q968Y9 Q9N5A0 Q9TYW1 Q9XW92 Q9XXU9	daf-2 fus-1 rdy-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-19 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
RHOU GTPase cycle	Arf-GAP domain-containing protein CHp/Wrch Rho-like protein homolog Calponin-homology (CH) domain-containing protein Cell division control protein 42 homolog E3 ubiquitin-protein ligase wwp-1 Ephrin receptor 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Inactive tyrosine-protein kinase kin-32 Intersectin-1 Microtubule-actin cross-linking factor 1 Myosin motor domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family PDZ domain-containing protein Partitioning defective protein 6 Phosphoinositide 3-kinase adapter subunit Probable clathrin heavy chain 1 Protein let-99 Rho-GAP domain-containing protein SH2 domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Sex muscle abnormal protein 5 Signal transducing adapter molecule 1 Spectrin alpha chain Spectrin beta chain Target of ERK kinase mpk-1 Thioredoxin-like protein UBA domain-containing protein Vang-like protein	A0A0K3AS36 A0A1N7SYP3 E0AHA7 G5EDP9 G5EES9 G5EFU0 G5EG81 G5EGQ3 H2KY90 H2KZH5 O01498 O17772 O61460 P29355 P34574 Q05062 Q17796 Q17850 Q19370 Q19467 Q19739 Q20398 Q21341 Q21408 Q21430 Q95PX0 Q95XA9 Q95YD4 Q9N2Z7 Q9NAN2 U4PBY2	CELE_T24B8.7 aap-1 cdc-42 chc-1 chw-1 gap-3 git-1 hgrs-1 hum-8 itsn-1 kin-32 let-99 magu-4 max-2 nck-1 pak-1 pak-2 par-6 pes-7 pix-1 pqn-19 sem-5 spc-1 srgp-1 stam-1 toe-2 txl txl-1 unc-70 vab-1 vab-10 vang-1 wwp-1	Caenorhabditis elegans
FLT3 Signaling	Discoidin domain-containing receptor tyrosine kinase B Forkhead box protein O Protein kinase domain-containing protein Protein kinase domain-containing protein Ras protein let-60 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Sex muscle abnormal protein 5 Son of sevenless homolog	A0A1I6CMA1 O16850 P22981 P29355 Q17941 Q21046 Q95ZV7 Q9N5D3 Q9XTG7	CELE_F59F5.3 akt-1 akt-2 daf-16 ddr-2 kin-36 let-341 let-60 lin-34 sem-5 sos-1 svh-4	Caenorhabditis elegans
Peroxisomal protein import	2-hydroxyacyl-CoA lyase Acyl-coenzyme A oxidase acox-1.1 Acyl-coenzyme A oxidase acox-1.2 Acyl-coenzyme A oxidase acox-1.3 Acyl-coenzyme A oxidase acox-1.4 Acyl-coenzyme A oxidase acox-3 Acyl-coenzyme A oxidase Acyl-coenzyme A thioesterase 1-like Alanine--glyoxylate aminotransferase Alpha-methylacyl-CoA racemase Amine oxidase domain-containing protein BAAT/acyl-CoA thioester hydrolase protein BAAT/acyl-CoA thioester hydrolase protein BAAT_C domain-containing protein Catalase Choline/carnitine acyltransferase domain-containing protein Choline/carnitine acyltransferase domain-containing protein D-amino-acid oxidase D-aspartate oxidase 1 D-aspartate oxidase 2 D-aspartate oxidase 3 Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Enoyl-CoA Hydratase FMN hydroxy acid dehydrogenase domain-containing protein Glutathione s-transferase kappa 2 Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] Lon protease homolog 2, peroxisomal Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Malonyl-CoA decarboxylase, mitochondrial MaoC-like domain-containing protein Mpv17-like protein Peroxisomal coenzyme A diphosphatase ndx-8 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisome assembly protein 12 Polyubiquitin-A Probable acyl-coenzyme A oxidase acox-1.5 Putative nudix hydrolase 7 Putative sarcosine oxidase RING-type E3 ubiquitin transferase TPR_REGION domain-containing protein UBA domain-containing protein Ubiquitin-conjugating enzyme E2 2 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized protein B0272.4 hydroxymethylglutaryl-CoA lyase palmitoyl-CoA hydrolase	A0A486WVT5 B1GRK5 B3WFZ3 G5EFP8 G5EG81 G5EGA6 H9G2T4 O01739 O01862 O16249 O17761 O45003 O45307 O62137 O62138 O62139 O62140 O76383 P0CG71 P34355 P35129 P37165 P41942 P49632 P91148 Q17474 Q17499 Q18006 Q18122 Q18355 Q18426 Q18916 Q18973 Q19058 Q19189 Q19564 Q19878 Q19951 Q20048 Q20959 Q20992 Q7YWV6 Q8MYL7 Q93839 Q93930 Q94055 Q95XG9 Q95XN1 Q9BIA9 Q9GYN3 Q9NA25 Q9XW87	B0272.4 B0395.3 C15B12.1 C17C3.1 C24A3.4 C31H5.6 C32D5.11 CELE_F41E6.5 CELE_F44E7.4 CELE_F58A6.1 CELE_K05B2.4 CELE_T05E7.1 CELE_T20B3.1 CELE_T24B8.7 CELE_W03D8.8 CELE_Y71G12B.10 T18D3.9 acl-7 acox-1 acox-1.1 acox-1.2 acox-1.3 acox-1.4 acox-1.5 acox-1.6 acox-2 acox-3 acox-4 acox-5 acox-6 acs-20 acs-22 agxt-1 ctl-3 daao-1 dapat ddo-1 ddo-2 ddo-3 dhrs-4 ech-8 gstk-2 hacl-1 hpo-15 idh-1 let-70 lonp-2 maoc-1 mlcd-1 ndx-7 ndx-8 prx-12 prx-13 prx-14 prx-5 ubc-2 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Sensory perception of salty taste	Acid-sensing ion channel 1 Amiloride-sensitive sodium channel Amiloride-sensitive sodium channel DEgenerin Like Degenerin deg-1 Degenerin del-1 Degenerin mec-10 Degenerin mec-4 Degenerin unc-8 Degenerin-like protein asic-1 Degenerin-like protein asic-2 Degenerin-like protein unc-105 EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein	O01635 P24585 P24612 P34886 P91835 Q09274 Q19038 Q19777 Q20852 Q21974 Q22851 Q8MPW0 Q93597 Q9U1T8 Q9U1T9 Q9XTS9	asic-1 asic-2 deg-1 degt-1 del-1 del-3 del-4 del-6 egas-1 egas-2 egas-3 egas-4 mec-10 mec-13 mec-4 unc-105 unc-8	Caenorhabditis elegans
P2Y receptors	G-protein coupled receptors family 1 profile domain-containing protein	H2KZ99	gnrr-4	Caenorhabditis elegans
Cell-extracellular matrix interactions	Calponin-homology (CH) domain-containing protein Integrin-linked protein kinase homolog pat-4 LIM domain-containing protein pin-2 LIM domain-containing protein unc-97 Paralyzed arrest at two-fold protein 6 Protein unc-112 UNC-34 Zyxin	G5EG53 O16785 P50464 Q18685 Q19157 Q9TZC4 Q9U3F4 U4PBJ9	fln-1 pat-4 pat-6 pin-2 unc-112 unc-34 unc-97 zyx-1	Caenorhabditis elegans
CS/DS degradation	Beta-hexosaminidase A Hyaluronidase Sulfatase N-terminal domain-containing protein	A0A4V0IJ66 G5ECE8 Q22492	Chnase chhy-1 hex-1 sul-3	Caenorhabditis elegans	G27025MB
Collagen degradation	Collagen alpha-1(IV) chain Ethanolamine-phosphate phospho-lyase homolog 1 Fibronectin type-III domain-containing protein MMP-like protein Matrix metalloproteinase-A Matrix metalloproteinase-B Matrix metalloproteinase-C Peptidase metallopeptidase domain-containing protein Uncharacterized protein VWFA domain-containing protein	G5EBU3 G5ECC4 G5EGA4 G5EGM1 O17913 O44836 P17139 P91408 Q18048 Q21182	C16E9.1 CELE_K03B8.6 clb-2 cle-1 emb-9 eppl-1 zmp-1 zmp-2 zmp-3 zmp-5 zmp-6	Caenorhabditis elegans
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Cyclin-C Cyclin-T1.1 Cyclin-T1.2 Cyclin-dependent kinase 8 Cyclin-like domain-containing protein Dwarfin sma-4 E2F/DP family winged-helix DNA-binding domain-containing protein Furin-like protease kpc-1 Mitogen-activated protein kinase mpk-1 Mothers against decapentaplegic homolog Polyubiquitin-A Probable cyclin-dependent kinase 9 Retinoblastoma-like protein homolog lin-35 Smad protein daf-8 Transcription factor dpl-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Yes-associated protein homolog 1	G5EDS9 G5EDT1 G5EF11 O17798 O17869 P0CG71 P34424 P34425 P37165 P39745 P45897 P49632 P90866 Q19404 Q21733 Q22703 Q9TVL3 Q9TYP2	ccnk-1 cdk-8 cdk-9 cem-3 cic-1 cit-1.1 cit-1.2 daf-8 dpl-1 efl-1 kpc-1 lin-35 mpk-1 sma-4 sur-1 tag-68 ubia ubib ubl-1 ubq-1 ubq-2 yap-1	Caenorhabditis elegans
N-glycan trimming and elongation in the cis-Golgi	Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q11068	gly-13	Caenorhabditis elegans
Sphingolipid catabolism	Aldehyde dehydrogenase Aldehyde dehydrogenase Alkaline ceramidase Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Phospholipid phosphatase homolog 1.2 homolog Sphingosine-1-phosphate lyase	A0A486WWU7 H2KZD1 O44555 O45145 Q10022 Q19403 Q9Y194	W02F12.2 alh-4 alh-5 plpp-1.1 plpp-1.2 plpp-1.3 spl-1	Caenorhabditis elegans

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