GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Neurexins and neuroligins	Disks large homolog 1 Moesin/ezrin/radixin homolog 1 Moesin/ezrin/radixin homolog 1 Neurexin-3-beta Neuroligin-1 Neuroligin-like protein glit-1 Protein lin-2 Protein shank SH3 domain-containing protein Sorbin and SH3 domain-containing protein 1 homolog	B7WN72 G5EC32 G5ECY0 G5EEG8 H2KZV9 I2HAJ6 P54936 Q18501 Q20826 Q9XTG1	C36E8.4 dlg-1 frm-1 frm-2 glit-1 lin-2 nlg-1 nrx-1 shn-1 sorb-1	Caenorhabditis elegans
Protein methylation	Electron transfer flavoprotein beta subunit lysine methyltransferase homolog Electron transfer flavoprotein subunit beta Elongation factor 1-alpha Protein-lysine N-methyltransferase CELE_F29B9.1 Protein-lysine N-methyltransferase M142.8 Protein-lysine methyltransferase C42C1.13 Transitional endoplasmic reticulum ATPase homolog 2	A7IQW5 O01503 P53013 P54812 Q5WRN3 Q9GYH9 Q9TXI4	C37A2.6 C42C1.13 CELE_F23C8.5 CELE_F29B9.1 M142.8 cdc-48.2 eft-3 eft-4	Caenorhabditis elegans
Stimuli-sensing channels	Acid-sensing ion channel 1-like Acid-sensing ion channel 1 Amiloride-sensitive sodium channel Amiloride-sensitive sodium channel Anoctamin Band 7 domain-containing protein Cation/H+ exchanger domain-containing protein Cation/H+ exchanger domain-containing protein Cation/H+ exchanger domain-containing protein Chloride channel protein clh-3 Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Coelomocyte uptake defective protein 15 DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Linked to Mechanosensation DEgenerin Linked to Mechanosensation Degenerin deg-1 Degenerin del-1 Degenerin mec-10 Degenerin mec-4 Degenerin unc-8 Degenerin-like protein asic-1 Degenerin-like protein asic-2 Degenerin-like protein del-10 Degenerin-like protein unc-105 E3 ubiquitin-protein ligase wwp-1 E3 ubiquitin-protein ligase EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein FLR-1 Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Polyubiquitin-A Protein tweety homolog 1 Raf homolog serine/threonine-protein kinase Serine/threonine-protein kinase sgk-1 Stomatin-1 Stomatin-2 Stomatin-3 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized transporter slc-17.2 Uncharacterized transporter slc-17.3	A0A061ACQ8 G3MU02 G5EC75 G5EFH3 G5EFS0 G5EG93 G5EGI5 G5EGT4 H2KYN8 H2KZQ1 H2L0J1 H2L2L3 O01537 O01635 O01664 O44130 O45402 P0CG71 P24585 P24612 P34272 P34886 P37165 P49632 P91100 P91102 P91103 P91835 Q03567 Q07292 Q09274 Q09322 Q10025 Q10048 Q18077 Q18651 Q19038 Q19200 Q19777 Q19958 Q20273 Q20332 Q20657 Q20852 Q21974 Q22851 Q22970 Q23514 Q23576 Q2PJ68 Q7YZV6 Q8I4F6 Q8MPW0 Q93205 Q93597 Q9BMK9 Q9N2Z7 Q9U1T8 Q9U1T9 Q9XTS9 Q9XU88	C38C10.2 CELE_F41E7.2 CELE_Y92H12A.2 acd-1 acd-2 acd-3 acd-4 acd-5 anoh-2 asic-1 asic-2 cima-1 clc-3 clh-2 clh-3 clh-4 clh-5 clh-6 cup-15 deg-1 degt-1 del-1 del-10 del-3 del-4 del-5 del-6 del-7 del-8 del-9 delm-1 delm-2 egas-1 egas-2 egas-3 egas-4 flr-1 lin-45 mec-10 mec-13 mec-4 raf-1 sgk-1 slc-17.1 slc-17.3 slc-17.4 slc-17.5 slc-17.6 slc-17.7 slc-17.8 slc-17.9 slc-9B.1 slc-9B.2 slc-9b.1 slc-9b.2 sto-1 sto-2 sto-3 sto-5 ttyh-1 ubia ubib ubl-1 ubq-1 ubq-2 unc-105 unc-8 wwp-1	Caenorhabditis elegans
Organic anion transporters	Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial dicarboxylate carrier Mitochondrial glutamate carrier 1 Potential vesicular glutamate transporter vglu-3 Probable vesicular glutamate transporter eat-4 Putative tricarboxylate transport protein, mitochondrial SLC (SoLute Carrier) homolog Sodium-coupled monocarboxylate transporter 2 Sodium-dependent multivitamin transporter Uncharacterized transporter slc-17.2 Uncharacterized transporter slc-17.3	G5EE96 G5EEK1 H2KYN8 H2KZQ1 O01537 O17394 O44130 P34272 P34519 P34644 P90992 Q03567 Q10046 Q10048 Q20847 Q23514 Q23576 Q23616 Q8I4F6 Q93540	C38C10.2 CELE_F52H2.4 K11H3.3 cima-1 eat-4 misc-1 slc-17.1 slc-17.3 slc-17.4 slc-17.5 slc-17.6 slc-17.7 slc-17.8 slc-17.9 slc-25A18.1 slc-25A18.2 slc-25a10 slc-25a18.1 slc-25a18.2 slc-5A12 vglu-2 vglu-3	Caenorhabditis elegans
Glutathione synthesis and recycling	5-oxoprolinase GCS light chain Gamma-glutamylcyclotransferase Gamma-glutamyltransferase Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Glutamate--cysteine ligase Glutathione synthetase Peptidase M20 dimerisation domain-containing protein gamma-glutamylcyclotransferase	A0A486WVP7 A0A9S2 A9CZN9 B5BM47 H2L030 H2L0B7 O18000 O18256 Q18596 Q20117 Q21549 Q9GZE8 Q9N5V4	C44B7.7 C53D5.5 CELE_E01A2.1 CELE_F22F7.7 CELE_H14N18.4 CELE_T03D8.6 CELE_T19H12.6 CELE_Y38F2AR.12 CELE_Y7A9A.1 CELE_Y97E10AR.2 gcs-1 gss-1 pes-9	Caenorhabditis elegans
Regulation of HSF1-mediated heat shock response	BAG domain-containing protein BAG family molecular chaperone regulator 1 DUF148 domain-containing protein DnaJ homolog subfamily C member 2 Glycogen synthase kinase-3 Heat shock 70 kDa protein 13 Heat shock 70 kDa protein C Heat shock protein 110 Heat shock protein hsp-1 Heat shock protein hsp-6 Heat shock transcription factor hsf-1 Hikeshi-like domain-containing protein J domain-containing protein MAP kinase-activated protein kinase mak-1 MAP kinase-activated protein kinase mak-2 Mitogen-activated protein kinase mpk-1 Protein kinase domain-containing protein Putative serine/threonine-protein kinase R03D7.5 STI1 domain-containing protein	G5EC99 G5EE04 G5EFT5 K8ERU5 O44739 O61980 P09446 P11141 P27420 P39745 Q05036 Q09595 Q20752 Q21360 Q93372 Q94216 Q965G5 Q9TY07 Q9U2Q9	C44H4.6 CELE_F11F1.1 CELE_F42A6.6 R03D7.5 bag-1 dnj-11 dnj-24 gsk-3 hip-1 hsf-1 hsp-1 hsp-110 hsp-3 hsp-6 hsp70a hsp70c hsp70f mak-1 mak-2 mot-2 mpk-1 sgg-1 stc-1 sur-1 unc-23	Caenorhabditis elegans
Disassembly of the destruction complex and recruitment of AXIN to the membrane	Axin-like protein pry-1 Caveolin-1 Caveolin-2 DiSHevelled related DiSHevelled related EGF-like domain-containing protein EGF-like domain-containing protein Frizzled-2 Glycogen synthase kinase-3 Protein kinase domain-containing protein Protein mom-5 Putative serine/threonine-protein kinase R03D7.5 Segment polarity protein dishevelled homolog mig-5	A0A0K3AUI8 A0A0K3AWM6 G5ECQ2 G5EFK8 O44191 O62090 Q09595 Q18239 Q18879 Q22227 Q93372 Q94051 Q9U2Q9	C44H4.6 CELE_F14B4.1 R03D7.5 cav-1 cav-2 cfz-2 dsh-1 dsh-2 gsk-3 mig-5 mom-5 pry-1 rme-2 sgg-1	Caenorhabditis elegans
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 BZIP domain-containing protein Cullin-1 Glycogen synthase kinase-3 MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Protein kinase domain-containing protein Protein skinhead-1 Putative serine/threonine-protein kinase R03D7.5 RING-box protein 1 Skp1-related protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A0M7REQ4 G5ECU1 O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P34707 P37165 P46502 P49632 P90868 P91477 Q04908 Q09595 Q10920 Q17389 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q23457 Q27488 Q93372 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9U2Q9 Q9XTT9 Q9XUV0	C44H4.6 CELE_F35G12.12 R03D7.5 cul-1 gsk-3 lin-19 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rbx-1 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 sgg-1 skn-1 sknr-1 skr-1 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
CRMPs in Sema3A signaling	Cyclin-dependent kinase 5 activator 1 Cyclin-dependent-like kinase 5 Dihydropyrimidinase 1 Dihydropyrimidinase 2 Fer-related kinase 1 Glycogen synthase kinase-3 Protein kinase domain-containing protein Protein unc-33 Putative serine/threonine-protein kinase R03D7.5 Sema domain-containing protein Sema domain-containing protein Semaphorin-1A Semaphorin-2A Tyrosine protein-kinase src-1	G5ECH7 G5EE56 Q01630 Q09595 Q17330 Q18677 Q21773 Q22146 Q22695 Q93372 Q95XP4 Q9TYS4 Q9U2Q9 U4PRY7	C44H4.6 R03D7.5 cdk-5 cdka-1 dhp-1 dhp-2 frk-1 gsk-3 mab-20 plx-1 sema-1a sgg-1 smp-1 smp-2 src-1 unc-33	Caenorhabditis elegans
Phase I - Functionalization of compounds	3-ketosteroid oxygenase AB hydrolase-1 domain-containing protein Aldehyde dehydrogenase Aldehyde dehydrogenase Alpha/beta hydrolase fold-3 domain-containing protein CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Cytochrome b5 heme-binding domain-containing protein Cytochrome b5 heme-binding domain-containing protein Epoxide hydrolase Epoxide hydrolase Gut esterase 1 MOSC domain-containing protein MOSC domain-containing protein MOSC domain-containing protein Probable cytochrome P450 CYP36A1 Probable cytochrome P450 cyp-35D1	A0A0M7RF98 A0A1C3NSL8 A0A486WWU7 A4UVK7 G5ECD0 G5EDJ7 G5EE22 H2KY69 H2KYS3 H2L0K7 H9G2Y9 O01302 O02627 O02628 O02641 O16220 O16362 O16482 O16670 O16671 O16673 O44555 O44649 O44650 O44651 O44652 O44655 O44656 O44657 O44658 O44704 O44706 O45364 O45394 O45659 O61204 O61935 O62377 O62378 P90771 P91321 P92016 Q04457 Q19839 Q20315 Q20976 Q21266 Q22008 Q23068 Q23268 Q27465 Q27470 Q27471 Q27482 Q27499 Q4LDP0 Q8MQ23 Q93315 Q965T7 Q9N4Q4 Q9N5I1 Q9TZ58 Q9XW75 U4PC34	C45B11.6 CELE_F22B8.7 CELE_F53E10.1 CELE_F56A11.5 CELE_F58B4.2 CELE_K01A2.5 CELE_W01A11.1 alh-4 alh-5 cest-1 cest-1.1 cest-1.2 cest-12 cest-13 cest-16 cest-17 cest-19 cest-2.1 cest-2.2 cest-2.3 cest-24 cest-26 cyp-23A1 cyp-23a1 cyp-33A1 cyp-33B1 cyp-33C1 cyp-33C11 cyp-33C12 cyp-33C2 cyp-33C3 cyp-33C4 cyp-33C5 cyp-33C6 cyp-33C7 cyp-33C8 cyp-33C9 cyp-33D1 cyp-33D3 cyp-33E1 cyp-33E2 cyp-33E3 cyp-33a1 cyp-33b1 cyp-33c1 cyp-33c11 cyp-33c12 cyp-33c2 cyp-33c3 cyp-33c4 cyp-33c5 cyp-33c6 cyp-33c7 cyp-33c8 cyp-33c9 cyp-33d1 cyp-33d3 cyp-33e1 cyp-33e2 cyp-33e3 cyp-34A1 cyp-34A10 cyp-34A2 cyp-34A5 cyp-34A6 cyp-34A7 cyp-34A8 cyp-34A9 cyp-34a1 cyp-34a10 cyp-34a2 cyp-34a4 cyp-34a5 cyp-34a6 cyp-34a7 cyp-34a8 cyp-34a9 cyp-35A1 cyp-35A2 cyp-35A3 cyp-35A4 cyp-35A5 cyp-35B1 cyp-35B2 cyp-35B3 cyp-35C1 cyp-35a1 cyp-35a2 cyp-35a3 cyp-35a4 cyp-35a5 cyp-35b1 cyp-35b2 cyp-35b3 cyp-35c1 cyp-35d1 cyp-36A1 cyp36a1 cytb-5.1 dach-1 daf-9 ges-1 trcs-1	Caenorhabditis elegans
Role of phospholipids in phagocytosis	PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein Phospholipase Probable phospholipase D F09G2.8 Protein kinase C-like 1 Protein kinase C-like 1B phospholipase A2	G5EDU3 H2KZ05 O17405 P34722 P34885 Q19056 Q8I4C7 Q95YD2	C45B2.6 CELE_E04F6.4 CELE_T05C3.6 CELE_Y51A2D.13 F09G2.8 PLD kin-13 pkc-1 pld-1 tpa-1 ttx-4	Caenorhabditis elegans
COPI-independent Golgi-to-ER retrograde traffic	Actin-related protein 10 Actin Dynactin subunit 1 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein heavy chain, cytoplasmic Dynein light chain 1, cytoplasmic Dynein light chain Dynein light chain Dynein light chain Dynein light chain Dynein light intermediate chain F-actin-capping protein subunit alpha F-actin-capping protein subunit beta Lissencephaly-1 homolog Polypeptide N-acetylgalactosaminyltransferase 3 Polypeptide N-acetylgalactosaminyltransferase 4 Probable dynactin subunit 2 Probable dynein light chain 2, cytoplasmic Protein bicaudal D homolog Rab3 GTPase-activating protein catalytic subunit Rab3 GTPase-activating protein regulatory subunit Ras-related protein Rab-18 Ras-related protein rab-6.1 Ras-related protein rab-6.2 WD_REPEATS_REGION domain-containing protein phospholipase A2	A0AAC1 E2JKZ0 G5ED34 O45087 P34213 P34678 P34685 P34686 Q09248 Q18194 Q19020 Q21557 Q22670 Q22782 Q22799 Q65XS9 Q7YTJ8 Q8I136 Q8MXS1 Q93538 Q95YD2 Q9GYR2 Q9N3F1 Q9N4I1 Q9NA98 Q9NDC9 Q9XWA8 V6CJ04	C45B2.6 arp-1 arp-11 bicd-1 cap-1 cap-2 dhc-1 dlc-1 dlc-2 dlc-3 dlc-4 dlc-5 dlc-6 dli-1 dnc-1 dnc-2 dnc-4 dnc-5 dnc-6 dyci-1 gly-3 gly-4 lis-1 pnm-1 rab-18 rab-6.1 rab-6.2 rbg-1 rbg-2	Caenorhabditis elegans
U12 Dependent Splicing	CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PSP proline-rich domain-containing protein Pre-mRNA-processing factor 6 Pre-mRNA-splicing factor 8 homolog Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein Sm D1 Probable small nuclear ribonucleoprotein Sm D2 Probable small nuclear ribonucleoprotein-associated protein B Probable splicing factor, arginine/serine-rich 2 Probable splicing factor, arginine/serine-rich 3 Probable splicing factor, arginine/serine-rich 4 Probable splicing factor, arginine/serine-rich 6 RNA helicase RNA helicase RNA polymerase Rpb4/RPC9 core domain-containing protein Small nuclear ribonucleoprotein Sm D3 Splicing factor 3B subunit 1 domain-containing protein Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Thioredoxin-like protein Tr-type G domain-containing protein Transcription initiation factor IIF subunit alpha U5 small nuclear ribonucleoprotein 200 kDa helicase WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein	G5EDV3 G5EEQ8 L8E6I4 O01763 O02092 O02097 O16997 O44985 O62213 P16356 P34369 P34659 P91306 P91398 P91918 Q09442 Q09511 Q10013 Q10578 Q17348 Q17558 Q17684 Q18409 Q18786 Q19211 Q19826 Q23120 Q23463 Q8MYM8 Q93338 Q93382 Q93594 Q95QN2 Q965S0 Q9GR61 Q9GRZ2 Q9N3C9 Q9N4G9 Q9N5K2 Q9NEW6 Q9U2G0 Q9U3I0 Q9XTU6 Q9XVH6	C46F11.4 ama-1 cbp-20 cbp-80 cey-1 cey-2 cey-3 cey-4 ddx-23 dib-1 eftu-2 gtf-2F1 gtf-2F2 gtf-2f1 gtf-2f2 ncbp-1 ncbp-2 prp-6 prp-8 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 rsp-2 rsp-3 rsp-4 rsp-6 sap-49 sftb-1 sftb-2 snr-1 snr-2 snr-3 snr-4 snr-5 snr-6 snr-7 snrp-200 snrp-40.1 snrp-40.2 srp-1 srp-2 srp-4 teg-4	Caenorhabditis elegans
Negative regulation of MAPK pathway	14-3-3-like protein 1 14-3-3-like protein 2 BRCA1-associated protein homolog 2 Dual specificity protein phosphatase lip-1 Kinase suppressor of Ras A Mitogen-activated protein kinase mpk-1 Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 Phosphatidylethanolamine-binding protein homolog F40A3.3 Polyubiquitin-A Probable serine/threonine-protein phosphatase PP2A regulatory subunit Progestin and AdipoQ Receptor family Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Raf homolog serine/threonine-protein kinase Ras protein let-60 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase par-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Serine/threonine-protein phosphatase 5 Tyrosine-protein phosphatase 1 Tyrosine-protein phosphatase domain-containing protein Tyrosine-protein phosphatase vhp-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A9UJN4 G5EFD2 G5EFV1 G5EGK8 O16264 O18178 O44514 P0CG71 P22981 P28191 P37165 P39745 P41932 P49632 P91267 Q07292 Q09543 Q10038 Q17446 Q20655 Q8MXI4 Q93344 Q95QN6 Q9NES8 Q9TW45 Q9U1V1 Q9U3L3 Q9XUJ0 Q9XX60 Q9XXC0 V6CIV8	C49C3.10 CELE_F21F3.2 CELE_W09H1.1 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 F40A3.3 brap-2 ftt-1 ftt-2 gska-3 gskl-2 ksr-1 let-60 let-92 lin-34 lin-45 lip-1 mpk-1 paa-1 paqr-3 par-1 par-5 pmk-1 pmk-2 pmk-3 pph-5 pptr-1 pptr-2 ptp-1 raf-1 sur-1 ubia ubib ubl-1 ubq-1 ubq-2 vhp-1	Caenorhabditis elegans
Myogenesis	Helix-loop-helix protein hlh-2 MEF2 transcription factor homolog Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 Myoblast determination protein 1 homolog Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein	G5EEG9 G5EFV1 O44514 P22980 P91267 Q17446 Q8MXI4 Q93344 Q9U325 Q9U3L3 Q9XX60 Q9XXC0	C49C3.10 CELE_F21F3.2 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 CeMef-2 gska-3 gskl-2 hlh-1 hlh-2 mef-2 pmk-1 pmk-2 pmk-3	Caenorhabditis elegans
ERK/MAPK targets	Mitogen-activated protein kinase mpk-1 Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 Mitogen-activated protein kinase Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Putative ribosomal protein S6 kinase alpha-1 Putative ribosomal protein S6 kinase alpha-2 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein phosphatase 2A catalytic subunit	A9UJN4 G5EFV1 G5EGK8 H2KYF8 O44514 P39745 P91267 Q09543 Q17446 Q18846 Q21734 Q8MXI4 Q93344 Q9U3L3 Q9XX60 Q9XXC0	C49C3.10 CELE_F21F3.2 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 gska-3 gskl-2 let-92 mpk-1 mpk-2 paa-1 pmk-1 pmk-2 pmk-3 pptr-2 rskn-1 rskn-2 sur-1	Caenorhabditis elegans
Dectin-2 family	C-type lectin domain-containing protein 87 C-type lectin domain-containing protein 88 C-type lectin domain-containing protein 91 C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Calcineurin-interacting protein 2 EGF-like domain-containing protein EGF-like domain-containing protein	D3KFV8 H2KZ07 O18076 O45275 P91214 Q18821 Q1ZXU1 Q20665 Q21146 Q86NG3 Q94417 Q9N4W5 Q9U2D6 Q9XUF9 Q9XVS3 Q9XVT9 Q9XWC4 Q9XX56	C49C3.4 CELE_F52E1.2 CELE_Y38H6C.8 clec-149 clec-196 clec-199 clec-202 clec-204 clec-224 clec-266 clec-45 clec-47 clec-86 clec-87 clec-88 clec-91 cnp-2 cpg-5 cpg-6 paml-1	Caenorhabditis elegans
RNA Polymerase II Transcription Termination	C2H2-type domain-containing protein Chromatin target of PRMT1 protein C-terminal domain-containing protein Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage stimulation factor 50 kDa subunit DUF3453 domain-containing protein Death domain-containing protein Histone RNA hairpin-binding protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PWI domain-containing protein Poly(A) polymerase Polyadenylation and cleavage factor homolog 11 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA-splicing factor SLU7 Probable cleavage and polyadenylation specificity factor subunit 1 Probable cleavage and polyadenylation specificity factor subunit 2 Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein-associated protein B Probable splicing factor, arginine/serine-rich 2 Probable splicing factor, arginine/serine-rich 3 Probable splicing factor, arginine/serine-rich 4 Probable splicing factor, arginine/serine-rich 6 Probable splicing factor, arginine/serine-rich 7 Protein CASC3 Protein clpf-1 Protein mago nashi homolog RNA helicase RNA-binding protein rnp-4 RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein SAP domain-containing protein Sm domain-containing protein Sm domain-containing protein Small nuclear ribonucleoprotein Sm D3 Spliceosome RNA helicase DDX39B homolog Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Suppressor of forked domain-containing protein THO complex subunit 2 THO complex subunit 5 THO complex subunit 7 homolog UPF3 domain-containing protein WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein pre-mRNA 3' end processing protein pfs-2	A0A164D3G3 C1P629 C2BR94 G5EDE4 O01159 O01763 O16929 O17403 O18219 O44729 O45577 O62185 P34498 P34659 P49029 P52874 P90978 P91867 P91918 Q09345 Q09511 Q09599 Q17348 Q18033 Q18212 Q18409 Q19864 Q19866 Q21155 Q21278 Q21559 Q21832 Q23120 Q7YTG9 Q7YWY5 Q8WQF3 Q93233 Q93594 Q93716 Q95PY8 Q9BL61 Q9GYQ8 Q9N3G0 Q9N4C2 Q9N4G9 Q9N5E3 Q9NEW6 Q9U2P3 Q9U2U0 Q9U3S3 Q9XTU6 U4PCM1 V6CKC3	C49H3.4 CELE_K07A1.15 CELE_Y53G8AR.6 CELE_Y57G11A.5 K07C5.6 RBM8 Y14 aly-3 casc-3 cbp-20 cbp-80 cdl-1 cfim-1 cfim-2 clpf-1 cpf-1 cpf-2 cpsf-1 cpsf-2 cpsf-3 cpsf-4 eif-4A3 fipp-1 hel-1 mag-1 mog-1 ncbp-1 ncbp-2 pabp-2 pap-1 pcf-11 pfs-2 prp-17 rnp-4 rnp-5 rsp-2 rsp-3 rsp-4 rsp-6 rsp-7 rsr-1 smg-4 snr-1 snr-2 snr-5 snr-6 snr-7 srp-1 srp-2 srp-4 suf-1 symk-1 thoc-1 thoc-2 thoc-3 thoc-5 thoc-7 uaf-1 uaf-2 znf-236	Caenorhabditis elegans
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	C2H2-type domain-containing protein Histone RNA hairpin-binding protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein-associated protein B Sm domain-containing protein Sm domain-containing protein Small nuclear ribonucleoprotein Sm D3	O01763 P34659 P91918 Q09599 Q17348 Q7YWY5 Q93594 Q9GYQ8 Q9N4G9 Q9XTU6 V6CKC3	C49H3.4 CELE_K07A1.15 cbp-20 cbp-80 cdl-1 ncbp-1 ncbp-2 snr-1 snr-2 snr-5 snr-6 snr-7 znf-236	Caenorhabditis elegans
SLBP independent Processing of Histone Pre-mRNAs	C2H2-type domain-containing protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein-associated protein B Sm domain-containing protein Sm domain-containing protein Small nuclear ribonucleoprotein Sm D3	O01763 P34659 P91918 Q17348 Q7YWY5 Q93594 Q9GYQ8 Q9N4G9 Q9XTU6 V6CKC3	C49H3.4 CELE_K07A1.15 cbp-20 cbp-80 ncbp-1 ncbp-2 snr-1 snr-2 snr-5 snr-6 snr-7 znf-236	Caenorhabditis elegans
Digestion of dietary carbohydrate	Alpha-amylase Glycoside hydrolase family 1 protein P-type domain-containing protein P-type domain-containing protein Probable endochitinase	P91982 Q11174 Q18758 Q19004 Q21750	C50B6.7 aagr-1 aagr-2 cht-1 klo-1	Caenorhabditis elegans	G58161NS G74621DY G80384UV G93924TT G96370VA
COPI-mediated anterograde transport	ADP-ribosylation factor 1-like 1 ADP-ribosylation factor 1-like 2 ADP-ribosylation factor Actin-related protein 10 Actin Alpha-soluble NSF attachment protein BET1 Coatomer subunit alpha Coatomer subunit beta Coatomer subunit epsilon Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 8 DUF727 domain-containing protein Dynactin subunit 1 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein heavy chain, cytoplasmic Dynein light chain 1, cytoplasmic Dynein light chain Dynein light chain Dynein light chain Dynein light chain Dynein light intermediate chain E3 ubiquitin-protein ligase arc-1 ER lumen protein-retaining receptor erd-2.1 ER lumen protein-retaining receptor erd-2.2 F-actin-capping protein subunit alpha F-actin-capping protein subunit beta GOLD domain-containing protein Gamma-soluble NSF attachment protein Golgi SNAP receptor complex member 1 Golgi SNAP receptor complex member 2 homolog memb-1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 homolog Golgin subfamily A conserved domain-containing protein PDZ GRASP-type domain-containing protein Probable coatomer subunit beta' Probable coatomer subunit delta Probable coatomer subunit gamma Probable coatomer subunit zeta Probable dynactin subunit 2 Probable dynein light chain 2, cytoplasmic Putative syntaxin-5 RAB family Spectrin alpha chain Spectrin beta chain Spectrin beta chain Suppressor/enhancer of lin-12 protein 9 Sushi domain-containing protein Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Transmembrane emp24 domain-containing protein bai Transmembrane protein 115 Uncharacterized protein C50C3.2 Uso1_p115_head domain-containing protein Vesicle-fusing ATPase WD_REPEATS_REGION domain-containing protein YKT6 (Yeast v-SNARE) homolog	A0A1N7SYP5 A0AAC1 E0AHA7 E2JKZ0 G5ED34 G5EE66 G5EEU1 G5EFK4 G5EFW3 G5EGG0 G5EGS5 O17528 O17901 O44502 O44738 O45087 O62246 P34367 P34685 P34686 P41941 P48583 P91151 Q09236 Q09248 Q09473 Q09654 Q10943 Q18194 Q18849 Q18921 Q19020 Q19989 Q1RPT8 Q20168 Q20546 Q20797 Q21270 Q21408 Q21444 Q21557 Q22498 Q22799 Q65XS9 Q6AW08 Q7YTJ8 Q94231 Q94392 Q95XZ0 Q95ZW1 Q9GYR2 Q9N3F1 Q9N3Y1 Q9N4H7 Q9N4I1 Q9NA98 Q9NEQ8 Q9TXZ9 Q9TYL9 Q9U3K1 Q9UAQ6 Q9XWA8	C50C3.2/C50C3.3 C54G4.4 CELE_F11A10.6 CELE_Y42H9AR.1 CELE_Y59A8B.25 CELE_Y59A8B.8 arc-1 arf-1 arf-1.1 arf-1.2 arf-3 arf-5 arl-4 arl-6 arp-1 arp-11 cap-1 cap-2 cfh-1 cgo-2 cog-2 cogc-1 cogc-2 cogc-3 cogc-4 cogc-5 cogc-6 cogc-8 copa-1 copb-1 copb-2 copd-1 cope-1 copg-1 copz-1 dhc-1 dlc-1 dlc-2 dlc-3 dlc-4 dlc-5 dlc-6 dli-1 dnc-1 dnc-2 dnc-4 dnc-5 dnc-6 dyci-1 erd-2 erd-2.1 erd-2.2 gbf-1 golg-2 gos-28 gosr-1 gosr-2.1 gs28 ldlc memb-1 nbet-1 nsf-1 phi-34 rab-1 sel-9 sma-1 snap-1 spc-1 syn-3 syx-5 tmed-10 tmed-3 unc-70 uso-1 ykt-6	Caenorhabditis elegans
RAF/MAP kinase cascade	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Inactive tyrosine-protein kinase kin-32 Kringle domain-containing protein Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Ral guanine nucleotide dissociation stimulator-like 1 Rap guanine nucleotide exchange factor Ras guanyl-releasing protein 3 Ras protein let-60 Ras-GEF domain-containing family member 1B Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5 Son of sevenless homolog Spectrin alpha chain Spectrin beta chain Spectrin beta chain Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Tyrosine-protein phosphatase Lar-like Uncharacterized protein C50C3.2	A0A1I6CMA1 E0AHA7 G5EDB9 G5EDP9 G5EE56 G5EEF1 G5EFK8 G5EFW3 H2KZU7 O44191 P22981 P24348 P29355 P34367 P39745 P91823 Q10656 Q11184 Q18758 Q19770 Q19852 Q21046 Q21408 Q94125 Q95YD4 Q95ZV7 Q9BMN8 Q9N413 Q9N5D3 Q9TZA0 Q9XVQ7 W6RS10	C50C3.2/C50C3.3 CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_R05G6.10 CELE_T22A3.6 aap-1 age-1 ddr-2 egl-15 egl-17 kin-32 kin-36 kin-7 klo-1 klo-2 let-23 let-341 let-60 let-756 lin-34 mpk-1 ptp-3 pvf-1 pxf-1 ra-gef rgef-1 rgl-1 rme-2 sem-5 sma-1 sos-1 spc-1 src-1 sur-1 svh-2 svh-4 unc-70	Caenorhabditis elegans
NCAM signaling for neurite out-growth	Inactive tyrosine-protein kinase kin-32 Mitogen-activated protein kinase mpk-1 Putative ribosomal protein S6 kinase alpha-2 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog Spectrin alpha chain Spectrin beta chain Spectrin beta chain Tyrosine protein-kinase src-1 Tyrosine-protein phosphatase Lar-like Uncharacterized protein C50C3.2	E0AHA7 G5EE56 G5EFW3 P22981 P29355 P34367 P39745 Q18846 Q21408 Q95YD4 Q9BMN8 Q9N5D3	C50C3.2/C50C3.3 kin-32 let-341 let-60 lin-34 mpk-1 ptp-3 rskn-2 sem-5 sma-1 sos-1 spc-1 src-1 sur-1 unc-70	Caenorhabditis elegans
Glycolysis	ATP-dependent 6-phosphofructokinase 1 ATP-dependent 6-phosphofructokinase 2 Enolase Fructose-bisphosphate aldolase 1 Fructose-bisphosphate aldolase 2 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase 1 Glyceraldehyde-3-phosphate dehydrogenase 2 Glyceraldehyde-3-phosphate dehydrogenase 3 Glyceraldehyde-3-phosphate dehydrogenase 4 Phosphoglucomutase-2 Phosphotransferase Phosphotransferase Phosphotransferase Probable ADP-dependent glucokinase Probable glucosamine-6-phosphate isomerase Probable phosphoglycerate kinase Pyruvate kinase Pyruvate kinase Triosephosphate isomerase	B7WNA0 O45934 P04970 P17329 P17330 P17331 P46563 P54216 P91427 Q10657 Q19440 Q23539 Q27483 Q27527 Q7K707 Q86S40 Q9N4A5 Q9TZL8 Q9XU15 Q9XVJ2	C50D2.7 CELE_Y43F4B.5 T03F6.3 aldo-1 aldo-2 enol-1 gpd-1 gpd-2 gpd-3 gpd-4 gpi-1 hxk-1 hxk-2 hxk-3 pfk-1.1 pfk-1.2 pgk-1 pyk-1 pyk-2 tpi-1	Caenorhabditis elegans	G58161NS

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