GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Phospholipase C-mediated cascade; FGFR4	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Protein let-756	G5EEF1 Q10656 Q11184 Q18758 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-756	Caenorhabditis elegans
HSF1 activation	Co-chaperone protein daf-41 Elongation factor 1-alpha Heat shock protein 90 Heat shock transcription factor hsf-1 Histone deacetylase domain-containing protein Transitional endoplasmic reticulum ATPase homolog 2	G5EFT5 P53013 P54812 Q18688 Q23280 Q9U266	cdc-48.2 daf-21 daf-41 eft-3 eft-4 hda-10 hsf-1 p23	Caenorhabditis elegans
G alpha (i) signalling events	CELF35-1 Dopamine receptor 2 Dopamine receptor 3 G protein gamma domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 3 profile domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein alpha-16 subunit Guanine nucleotide-binding protein alpha-4 subunit Guanine nucleotide-binding protein alpha-6 subunit Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma Muscarinic acetylcholine receptor gar-3 Neuropeptide receptor 18 Probable G-protein coupled receptor C06G4.5 Probable metabotropic glutamate receptor mgl-1 RGS domain-containing protein RGS domain-containing protein Regulator of G-protein signaling 7 Regulator of G-protein signaling egl-10 Regulator of G-protein signaling rgs-10 Regulator of G-protein signaling rgs-11 Regulator of G-protein signaling rgs-1 Regulator of G-protein signaling rgs-2 Regulator of G-protein signaling rgs-3 Regulator of G-protein signaling rgs-6 Regulator of G-protein signaling rgs-7 Regulator of G-protein signaling rgs-9 SERPIN domain-containing protein SERPIN domain-containing protein Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Tetratricopeptide repeat protein 28 Tyramine receptor Ser-2 Tyramine receptor tyra-2 Tyrosine protein-kinase src-1	A0A0K3AXD3 A0A3B1DQQ4 A0A5S9MNH1 A1IMB8 A9Z1L1 E7EM37 G5ECB2 G5ECK9 G5ECT6 G5ECY2 G5ECZ3 G5EE40 G5EE56 G5EFH4 G5EGH0 H2KZ99 H2L0Q3 O01818 O02213 O17365 O17589 O18014 O45520 O45523 O45524 P17343 P34295 P34311 P49808 P49809 P54406 Q09502 Q09630 Q18287 Q18312 Q18563 Q19084 Q19651 Q19779 Q19955 Q1ZXT2 Q20636 Q20827 Q20841 Q23033 Q23376 Q6RYS9 Q7JP61 Q8MPR3 Q8WQC0 Q93743 Q9BIG5 Q9N2V6 Q9N452 Q9U7D5 Q9XVQ1	C06G4.5 C28G1.2 CELE_F15D3.4 CELE_F35H10.10 CELE_F44G3.7 CELE_F55D10.4 CELE_F57C9.6 CELE_ZK813.5 ador-1 ags-3 dop-2 dop-2L dop-3 eat-11 eat-16 egl-10 gar-3 gbb-1 gbb-2 gbp-2 gnrr-4 gpa-16 gpa-4 gpa-6 gpb-1 gpb-2 gpc-1 gpc-2 gtr-1 mgl-1 mgl-3 npr-16 npr-18 npr-23 npr-24 npr-25 npr-26 npr-28 octr-1 rgs-1 rgs-10 rgs-11 rgs-2 rgs-3 rgs-4 rgs-6 rgs-7 rgs-8.1 rgs-8.2 rgs-9 ser-2 ser-4 spn-1 src-1 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 tyra-2	Caenorhabditis elegans
Degradation of the extracellular matrix	Cathepsin L-like Contactin rig-6 Disintegrin and metalloproteinase domain-containing protein adm-2 Disintegrin and metalloproteinase domain-containing protein unc-71 Ig-like domain-containing protein Kringle domain-containing protein MMP-like protein Matrix metalloproteinase-A Matrix metalloproteinase-B Matrix metalloproteinase-C Peptidase M12B domain-containing protein Peptidase metallopeptidase domain-containing protein Titin homolog Uncharacterized protein Zinc metalloproteinase nas-39	C6KRM7 G4SLH0 G5EBU3 G5ECC4 G5EDW5 G5EFD5 G5EGM1 H2KZ60 O17913 O44836 O45734 P91823 Q20176 Q21182 Q9N5X7	CELE_K03B8.6 CELE_T22A3.6 adm-1 adm-2 cpl-1 nas-39 rig-5 rig-6 tag-275 ttn-1 unc-71 zmp-1 zmp-2 zmp-3 zmp-5 zmp-6	Caenorhabditis elegans
L13a-mediated translational silencing of Ceruloplasmin expression	60S ribosomal protein L29 COP9/Signalosome and eIF3 complex-shared subunit 1 Eukaryotic initiation factor 4A Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 3 30 kDa subunit Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 4C Eukaryotic translation initiation factor 4E-1 Eukaryotic translation initiation factor 4E-2 Eukaryotic translation initiation factor 4E-3 Eukaryotic translation initiation factor 4E-5 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23B Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5B Large ribosomal subunit protein uL6 MIF4G domain-containing protein Plectin/S10 N-terminal domain-containing protein Polyadenylate-binding protein RNA helicase Ribosomal Protein, Small subunit Ribosomal protein L37 Serine/arginine-rich splicing factor 2 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS9 Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein protein-synthesizing GTPase	A0A486WX07 G4S0D4 O01504 O01692 O01802 O01868 O01869 O01974 O02056 O02328 O02639 O17218 O17570 O18240 O18650 O44480 O45226 O45499 O45551 O45781 O45946 O61820 O61955 O62388 P27639 P30642 P34334 P34339 P34662 P37165 P46769 P47991 P48150 P48152 P48154 P48156 P48158 P48166 P49041 P49180 P49181 P49196 P49197 P49405 P50880 P51403 P51404 P52814 P52819 P52821 P56570 P61866 P90983 P91053 P91055 P91128 P91374 P91913 P91914 Q09533 Q18967 Q19162 Q19706 Q19869 Q19877 Q1XFY9 Q20206 Q20228 Q20647 Q20935 Q21230 Q21693 Q21930 Q22054 Q22716 Q23312 Q27389 Q8WQA8 Q93572 Q94261 Q95QW0 Q95XR0 Q95Y04 Q95Y90 Q965S8 Q966C6 Q9BKU3 Q9BKU5 Q9BL19 Q9N3X2 Q9N4I4 Q9NEN6 Q9TXP0 Q9TXU7 Q9U2A8 Q9U302 Q9U332 Q9XUP3 Q9XVE9 Q9XVF7 Q9XVP0 Q9XWI6 Q9XWP7 Q9XWS4	C16C8.14 C16C8.16 C16C8.20 C37A2.7 CELE_F57B9.3 CELE_W01D2.1 CELE_Y37E3.8 cif-1 csn-7 drr-2 egl-45 eif-1.A eif-1.a eif-2alpha eif-2beta eif-2gamma eif-3.A eif-3.B eif-3.C eif-3.D eif-3.E eif-3.F eif-3.G eif-3.H eif-3.I eif-3.J eif-3.K eif-3.L eif-3.M eif-3.j ife-1 ife-2 ife-3 ife-5 ifg-1 iftb-1 inf-1 pab-1 rla-0 rla-1 rpa-0 rpa-1 rpl-1 rpl-10 rpl-10a rpl-11.2 rpl-12 rpl-13 rpl-14 rpl-15 rpl-16 rpl-17 rpl-18 rpl-19 rpl-2 rpl-20 rpl-21 rpl-22 rpl-23 rpl-24.1 rpl-25.2 rpl-26 rpl-27 rpl-28 rpl-29 rpl-3 rpl-30 rpl-31 rpl-32 rpl-33 rpl-35 rpl-36 rpl-36.A rpl-37a rpl-38 rpl-39 rpl-4 rpl-41 rpl-43 rpl-5 rpl-6 rpl-7 rpl-7A rpl-8 rpl-9 rps-0 rps-1 rps-10 rps-11 rps-12 rps-13 rps-14 rps-15 rps-16 rps-17 rps-18 rps-19 rps-2 rps-20 rps-21 rps-22 rps-23 rps-24 rps-25 rps-26 rps-27 rps-28 rps-29 rps-3 rps-4 rps-5 rps-6 rps-7 rps-8 rps-9 ubl-1	Caenorhabditis elegans
Amino acids regulate mTORC1	DAF-15 Folliculin GTP-binding protein Rheb homolog 1 GTP-binding protein Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 Ragulator complex protein LAMTOR2 homolog Ras-related GTP-binding protein C Sodium-coupled neutral amino acid transporter 9 homolog Target of rapamycin complex subunit lst8 Target of rapamycin homolog UDENN FNIP1/2-type domain-containing protein V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGB3 G5EGP4 H2L0I8 O17268 P30628 P34443 P34462 P91040 P91303 Q19425 Q19626 Q20591 Q22494 Q22743 Q23680 Q68TI8 Q8WQG5 Q95Q95 Q95X44 Q95YD5 Q9N2U6 Q9N5A0 Q9XW92 Q9XXU9 S6FMZ4	CeTor F13H10.3 daf-15 flcn-1 fnip-2 fus-1 let-363 lmtr-2 lmtr-3 lmtr-5 mlst-8 raga-1 ragc-1 rdy-1 rheb-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
Sodium/Proton exchangers	Na(+)/H(+) exchanger protein 2 Na(+)/H(+) exchanger protein 7 Probable Na(+)/H(+) antiporter nhx-3 Probable Na(+)/H(+) antiporter nhx-9 Sodium/hydrogen exchanger Sodium/hydrogen exchanger Sodium/hydrogen exchanger	G5EBK1 G5EBN7 G5ED88 H2L039 O16452 P35449 Q8T5S1	nhx-2 nhx-3 nhx-5 nhx-6 nhx-7 nhx-8 nhx-9 pbo-4	Caenorhabditis elegans
SHC-mediated cascade:FGFR2	EGL-17 Myoblast growth factor receptor egl-15 Protein let-756 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog	G5EEF1 P22981 P29355 Q10656 Q11184 Q9N5D3	egl-15 egl-17 let-341 let-60 let-756 lin-34 sem-5 sos-1	Caenorhabditis elegans
SLBP independent Processing of Histone Pre-mRNAs	C2H2-type domain-containing protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein-associated protein B Sm domain-containing protein Sm domain-containing protein Small nuclear ribonucleoprotein Sm D3	O01763 P34659 P91918 Q17348 Q7YWY5 Q93594 Q9GYQ8 Q9N4G9 Q9XTU6 V6CKC3	C49H3.4 CELE_K07A1.15 cbp-20 cbp-80 ncbp-1 ncbp-2 snr-1 snr-2 snr-5 snr-6 snr-7 znf-236	Caenorhabditis elegans
Asymmetric localization of PCP proteins	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Frizzled-2 Frizzled-4 LIM zinc-binding domain-containing protein MPN domain-containing protein PCI domain-containing protein Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Protein Wnt-2 Protein mom-5	A0A0K3AWM6 G5ECQ2 G5EDV1 H2KYA1 O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P34889 P46502 P90868 P91477 Q04908 Q10920 Q17971 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q27488 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9XTT9 Q9XUV0	C14C10.5 CELE_F35G12.12 cfz-2 cwn-2 lin-17 mom-5 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 prkl-1 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 wnt-2	Caenorhabditis elegans
RHO GTPases Activate Formins	Actin-1 Actin-2 Actin-3 Actin-4 Cell division control protein 42 homolog DiSHevelled related DiSHevelled related FH2 domain-containing protein FH2 domain-containing protein Formin-homology and zinc finger domains protein 1 Ras-like GTP-binding protein rhoA Ras-related protein ced-10 Rho-GAP domain-containing protein Segment polarity protein dishevelled homolog mig-5 Tyrosine protein-kinase src-1 WAPL domain-containing protein	A0A0K3AUI8 D6VPA1 G5EE56 P0DM41 P0DM42 P10984 P10986 P34489 Q03206 Q05062 Q18239 Q19370 Q19479 Q22038 Q22227 Q7JP75	act-1 act-2 act-3 act-4 cdc-42 ced-10 cyk-1 daam-1 dsh-1 dsh-2 fozi-1 inft-2 mig-5 rac-1 rho-1 rhoa src-1 srgp-1	Caenorhabditis elegans
Switching of origins to a post-replicative state	DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM7 DNA replication licensing factor mcm-4 DNA replication licensing factor mcm-5 DNA replication licensing factor mcm-6	O16297 P34647 Q21902 Q95XQ8 Q9XVR7 Q9XXI9	MCM7 let-358 lin-6 mcm-2 mcm-3 mcm-4 mcm-5 mcm-6 mcm-7	Caenorhabditis elegans
MET Receptor Activation	Kringle domain-containing protein Protein kinase domain-containing protein Tyrosine-protein kinase receptor svh-2	H2KZU7 P91823 Q9XVQ7	CELE_F11E6.8 CELE_T22A3.6 svh-2	Caenorhabditis elegans
Class A/1 (Rhodopsin-like receptors)	G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein	H2KZ99 O18014 Q19779 Q1ZXT2 Q20827	CELE_F55D10.4 ador-1 gnrr-4 gtr-1 npr-25	Caenorhabditis elegans
Cation-coupled Chloride cotransporters	K+/Cl-Cotransporter K+/Cl-Cotransporter Potassium/chloride cotransporter 3 Solute carrier family 12 member 1 Solute carrier family 12 protein B0303.11	H2KZC3 H8ESD5 P34261 Q09573 S6FWN4	B0303.11 kcc-1 kcc-2 kcc-3 nkcc-1	Caenorhabditis elegans
KEAP1-NFE2L2 pathway	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 BZIP domain-containing protein Cullin-3 MPN domain-containing protein Nuclear protein localization protein 4 homolog 2 PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Protein kinase C-like 3 Protein lgg-2 Protein skinhead-1 RING-box protein 1 RING-type domain-containing protein Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Sestrin homolog Transitional endoplasmic reticulum ATPase homolog 2 Ubiquitin fusion degradation protein 1 homolog Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein ZZ-type domain-containing protein	A0A0M7REQ4 O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P34707 P37165 P46502 P49632 P54812 P90868 P91477 Q04908 Q10920 Q17391 Q17746 Q17941 Q17971 Q18115 Q18787 Q19266 Q19324 Q19584 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q23457 Q23536 Q27488 Q95005 Q95008 Q95PZ7 Q95QZ9 Q966I8 Q9GZH5 Q9N3T6 Q9N4D6 Q9N599 Q9XTG7 Q9XTT9 Q9XUV0	C14C10.5 CELE_F35G12.12 CELE_Y47G6A.14 aPKC akt-1 akt-2 cdc-48.2 cul-3 gldi-4 lgg-2 npl-4.2 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 pkc-3 psmd-9 psme-3 rbx-1 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 sesn-1 skn-1 sknr-1 ubia ubib ubl-1 ubq-1 ubq-2 ufd-1	Caenorhabditis elegans
Synthesis of 5-eicosatetraenoic acids	Arylesterase Arylesterase Mechanosensory abnormality protein 6 PON (Paraoxonase) and MEC-6 Like SMP-30/Gluconolactonase/LRE-like region domain-containing protein	B1V898 O01811 Q21427 Q2V071 Q966L1	mec-6 poml-1 poml-2 poml-3 poml-4	Caenorhabditis elegans
RHOH GTPase cycle	ANK_REP_REGION domain-containing protein Amino acid transporter Amino acid transporter Anion exchange protein Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 Caveolin-1 Caveolin-2 Excitatory amino acid transporter Glutamate carboxypeptidase 2 homolog Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial N-acetylated-alpha-linked acidic dipeptidase 2 Probable methionine synthase Probable rho GDP-dissociation inhibitor Protein FAM91A1 Protein kinase domain-containing protein Putative NipSnap protein K02D10.1 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rap-GAP domain-containing protein Ras-related protein Rab-18 Ras-related protein Rab-7a Ras-related protein ced-10 Ras-related protein rac-2 Rho-associated protein kinase let-502 Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Stomatin-2 Synaptobrevin-1 Transitional endoplasmic reticulum ATPase homolog 2 Tyrosine protein-kinase src-1 Tyrosine-protein kinase csk-1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase UBX domain-containing protein 2 Vang-like protein WD_REPEATS_REGION domain-containing protein	A0A061ADQ6 A0A0K3ARA3 B3WFV9 G5EBM6 G5ECJ6 G5EE56 G5EFU0 G5EGQ3 H2KY90 H2KZ40 O02495 O18210 O44326 O62219 P34492 P54812 P91406 P92199 Q03206 Q09582 Q10901 Q10953 Q17850 Q18462 Q18825 Q18879 Q19958 Q20496 Q21353 Q21751 Q22682 Q23146 Q23571 Q23595 Q93332 Q94051 Q94124 Q9BL44 Q9N2W5 Q9N4S6 Q9U3B5 Q9UAY8 Q9XW34 V6CLC2	C34F11.5 CELE_F33H2.2 CELE_K09B11.5 CELE_R151.1 CELE_T25B9.5 CELE_Y110A7A.9 CELE_Y52D5A.2 CELE_Y69E1A.3 CELE_Y71H2AM.12 CELE_ZK792.4 K02D10.1 abts-1 bar-1 cav-1 cav-2 cdc-48.2 ced-10 csk-1 dbt-1 gcp-2.1 gcp-2.2 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 hgap-1 hmp-2 kin-21 let-502 max-2 metr-1 pak-1 pak-2 pvl-1 rab-7 rac-1 rac-2 rhi-1 snb-1 spy-1 src-1 sto-2 ubxn-2 vang-1 wrm-1	Caenorhabditis elegans
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor gar-3	Q9U7D5	gar-3	Caenorhabditis elegans
RAF activation	14-3-3-like protein 1 14-3-3-like protein 2 BRCA1-associated protein homolog 2 GTP binding protein Kinase suppressor of Ras A Leucine-rich repeat protein soc-2 Mitochondrial prohibitin complex protein 1 Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Raf homolog serine/threonine-protein kinase Ras protein let-60 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase par-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Serine/threonine-protein phosphatase PP1-alpha Serine/threonine-protein phosphatase	A9UJN4 G5EC18 G5EFD2 G5EGA7 G5EGK8 O18178 P22981 P41932 Q07292 Q09543 Q20655 Q22875 Q27497 Q95QN6 Q9BKU4 Q9NAC7 Q9TW45	CELE_Y53F4B.1 Ras2 brap-2 ftt-1 ftt-2 gsp-1 ksr-1 let-60 let-92 lin-34 lin-45 paa-1 par-1 par-5 phb-1 pph-1 pptr-1 pptr-2 raf-1 ras-2 soc-2 sur-8	Caenorhabditis elegans
Signaling by EGFR	EGF-like domain-containing protein EGF-like domain-containing protein Leucine-rich repeats and immunoglobulin-like domains protein sma-10 Receptor tyrosine-protein kinase let-23 Tyrosine protein-kinase src-1 WD_REPEATS_REGION domain-containing protein	E0R7L2 G5EE56 G5EFK8 O44191 P24348 Q965M2	CELE_F14B4.1 CELE_Y111B2A.12 kin-7 let-23 rme-2 sma-10 src-1	Caenorhabditis elegans
Sema3A PAK dependent Axon repulsion	Fer-related kinase 1 Ras-related protein ced-10 Sema domain-containing protein Sema domain-containing protein Semaphorin-1A Semaphorin-2A Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Tyrosine protein-kinase src-1	G5EE56 G5EGQ3 Q03206 Q17330 Q17850 Q22146 Q95XP4 Q9TYS4 U4PRY7	ced-10 frk-1 mab-20 max-2 pak-1 plx-1 rac-1 sema-1a smp-1 smp-2 src-1	Caenorhabditis elegans
Rap1 signalling	14-3-3-like protein 1 14-3-3-like protein 2 Raf homolog serine/threonine-protein kinase Rap guanine nucleotide exchange factor 1 Rap-GAP domain-containing protein Rap-GAP domain-containing protein Ras guanyl-releasing protein 3 Ras-related protein Rap-1 cAMP-dependent protein kinase catalytic subunit cGMP-dependent protein kinase egl-4	H2L055 H2L2C2 O76360 P21137 P34578 P41932 Q07292 Q18246 Q19770 Q20655	CELE_F53A10.2 cgk-1 egl-4 epac-1 ftt-1 ftt-2 kin-1 lin-45 odr-9 par-5 raf-1 rap-1 rgef-1 sipa-1	Caenorhabditis elegans
MET activates PTK2 signaling	Inactive tyrosine-protein kinase kin-32 Integrin alpha ina-1 Integrin alpha pat-2 Kringle domain-containing protein Multiple epidermal growth factor-like domains protein 6 Protein kinase domain-containing protein Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Uncharacterized integrin beta-like protein C05D9.3	G5EE56 G5EFX3 H2KZU7 P34446 P91823 Q03600 Q95YD4 Q9GYK2 Q9XVQ7	C05D9.3 CELE_F11E6.8 CELE_T22A3.6 CELE_Y64G10A.7 ina-1 kin-32 pat-2 src-1 svh-2	Caenorhabditis elegans
MET activates RAS signaling	Kringle domain-containing protein Protein kinase domain-containing protein Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog Tyrosine-protein kinase receptor svh-2	H2KZU7 P22981 P29355 P91823 Q9N5D3 Q9XVQ7	CELE_F11E6.8 CELE_T22A3.6 let-341 let-60 lin-34 sem-5 sos-1 svh-2	Caenorhabditis elegans

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