GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **499** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Unblocking of NMDA receptors, glutamate binding and activation	Alpha-actinin, sarcomeric Calcium/calmodulin-dependent protein kinase type II Disks large homolog 1 EF-hand domain-containing protein GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 LITAF domain-containing protein NMDA-type ionotropic glutamate receptor NMR-2 Protein lap1	A0A1T5HUM0 G5ECY0 G5EEH3 G5EGQ9 O01623 O61967 O62305 P34299 Q10914 Q17697 Q18136 Q21415 Q23158 Q8MXV8	atn-1 cal-5 dlg-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 let-413 nmr-1 nmr-2 unc-43	Caenorhabditis elegans
Digestion of dietary carbohydrate	Alpha-amylase Glycoside hydrolase family 1 protein P-type domain-containing protein P-type domain-containing protein Probable endochitinase	P91982 Q11174 Q18758 Q19004 Q21750	C50B6.7 aagr-1 aagr-2 cht-1 klo-1	Caenorhabditis elegans	G58161NS G74621DY G80384UV G93924TT G96370VA
VEGFR2 mediated vascular permeability	Alpha-catenin-like protein hmp-1 Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 EF-hand domain-containing protein Heat shock protein 90 Juxtamembrane domain-associated catenin Protein nipi-3 Protein vav-1 RICTOR_N domain-containing protein Ras-related protein ced-10 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Stress-activated map kinase-interacting protein 1 homolog Target of rapamycin complex subunit lst8 Target of rapamycin homolog non-specific serine/threonine protein kinase	G5EED4 G5EFN2 G5EGQ3 O44326 P90947 P91040 Q03206 Q10953 Q17850 Q17941 Q18136 Q18688 Q18825 Q45FX5 Q95Q95 Q9NA80 Q9U308 Q9UA62 Q9XTG7	CELE_W04B5.5 CeTor akt-1 akt-2 bar-1 cal-5 ced-10 daf-21 hmp-1 hmp-2 jac-1 let-363 max-2 mlst-8 nipi-3 pak-1 pvl-1 rac-1 rict-1 sinh-1 spy-1 vav-1 wrm-1	Caenorhabditis elegans
Lysosomal oligosaccharide catabolism	Alpha-mannosidase Probable beta-mannosidase	Q20829 Q93324	C33G3.4 aman-1	Caenorhabditis elegans	G00027MO G28233ME G70323CJ G90333CG
COPII-mediated vesicle transport	Alpha-soluble NSF attachment protein BET1 Cathepsin Z-1 DUF727 domain-containing protein ERGIC-53-like protein Fibronectin type-III domain-containing protein GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Gamma-soluble NSF attachment protein Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 Golgi SNAP receptor complex member 2 homolog memb-1 Golgin subfamily A conserved domain-containing protein L-type lectin-like domain-containing protein PDZ GRASP-type domain-containing protein Probable trafficking protein particle complex subunit 2 Protein SEC13 homolog Protein cornichon homolog 1 Protein tfg-1 Protein transport protein SEC23 Protein transport protein Sec24C Protein transport protein sec-16A.1 Protein transport protein sec16 Putative syntaxin-5 RAB family Rab-GAP TBC domain-containing protein SERPIN domain-containing protein SERPIN domain-containing protein Sec1 family domain-containing protein 1 Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Small COPII coat GTPase SAR1 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 3 homolog Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Trafficking protein particle complex subunit Uso1_p115_head domain-containing protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein YKT6 (Yeast v-SNARE) homolog Yeast SEC homolog	A0A1T5HUM0 A9Z1L1 B1GRL5 B1V899 G4SNB8 G5ECY2 G5EDE8 G5EE40 G5EEU1 G5EFH4 G5EFY6 G5EGA4 G5EGG0 G5EGP8 H2KZQ8 O01623 O02173 O17365 O45520 P34299 P34605 P34643 P41941 Q10914 Q17697 Q18287 Q18921 Q19371 Q19651 Q19989 Q1RPT8 Q20100 Q20364 Q20797 Q21115 Q21415 Q22170 Q22361 Q23368 Q23445 Q8MXV8 Q93330 Q94241 Q94392 Q9N3Y1 Q9N4A7 Q9NA81 Q9NEQ8 Q9TXZ9 Q9U1W1 Q9U2Z1 Q9UAQ6 Q9XU81 Q9XVQ1 Q9XWI2	C28G1.2 CELE_F15D3.4 CELE_F44G3.7 CELE_T10F2.5 CELE_Y42H9AR.1 CELE_Y59A8B.25 CELE_Y59A8B.8 CeSec13R cle-1 cni-1 cnih-2 cpz-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 golg-2 gosr-2.1 ile-1 ile-2 memb-1 nbet-1 npp-20 nsf-1 rab-1 sar-1 sec-12 sec-13 sec-16 sec-16A.1 sec-16A.2 sec-16a.2 sec-22 sec-23 sec-24.1 sec-24.2 sec-31 sedl-1 sly-1 snap-1 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 syn-3 syx-5 tbc-20 tfg-1 trpp-1 trpp-10 trpp-3 trpp-4 trpp-5 trpp-6 trpp-9 uso-1 ykt-6	Caenorhabditis elegans
Interconversion of polyamines	Amine oxidase domain-containing protein Thialysine N-epsilon-acetyltransferase	O17731 O76383	D2023.4 hpo-15	Caenorhabditis elegans
PAOs oxidise polyamines to amines	Amine oxidase domain-containing protein	O76383	hpo-15	Caenorhabditis elegans
Amino acid transport across the plasma membrane	Amino acid transporter transmembrane domain-containing protein Amino acid transporter transmembrane domain-containing protein Amino acid transporter transmembrane domain-containing protein Amino acid transporter transmembrane domain-containing protein Amino acid transporter transmembrane domain-containing protein Amino acid transporter Amino acid transporter Excitatory amino acid transporter Mitochondrial carnitine/acylcarnitine carrier protein CACL Probable amino acid transporter skat-1 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Sodium-dependent nutrient amino acid transporter 1 Sodium-dependent transporter snf-5 Transporter Transporter	G4SQY7 G5EBM5 G5EE39 O18210 O45936 O62286 P34479 P90890 Q10901 Q18595 Q21353 Q21751 Q22682 Q8I4M0 Q9UAY8 Q9XUG5 Q9XX44	glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 skat-1 slc-25A29 slc-25a29 slc-36.1 slc-36.2 slc-36.3 slc-36.4 slc-36.5 snf-2 snf-5 snf-7 snf-9	Caenorhabditis elegans
RAC1 GTPase cycle	Amino acid transporter Amino acid transporter Arf-GAP domain-containing protein C2 DOCK-type domain-containing protein CED-5 CRAL-TRIO domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Chimerin 2 Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Excitatory amino acid transporter F-BAR domain-containing protein FYVE, RhoGEF and PH domain-containing protein tag-77 Formin-homology and zinc finger domains protein 1 GTPase-activating protein pac-1 Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor Guanine nucleotide-binding protein alpha-12 subunit MAGUK family Membrane-associated protein gex-3 Moesin/ezrin/radixin homolog 1 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Partitioning defective protein 6 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein ECT2 Protein let-99 Protein unc-112 Protein vav-1 Protein vav Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rac GTPase-activating protein 1 Ras-related protein Rab-7a Ras-related protein ced-10 Rho GTPase-activating protein 20 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH2 domain-containing protein SH3 domain-containing protein SH3 domain-containing protein START domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase mrck-1 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Son of sevenless homolog Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A0K3AR51 A0A2K5AU23 A0A4V0ILM7 A5PEW5 A5Z2X2 F0IWT2 G5EDP9 G5EDU3 G5EEN3 G5EEN8 G5EF62 G5EF80 G5EFE1 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 O01583 O01847 O02495 O17772 O17905 O18210 O44518 O45611 O61460 O61528 P03949 P34288 P34489 P46549 P46941 P55163 P91406 Q03206 Q05062 Q10901 Q10929 Q17850 Q18685 Q18879 Q19370 Q19467 Q19572 Q20440 Q20487 Q20496 Q21025 Q21341 Q21353 Q21430 Q21751 Q22682 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q94125 Q95XW5 Q965J0 Q965N4 Q9GYK2 Q9N5D3 Q9NAN2 Q9U364 Q9UAY8 Q9XUS9 Q9XVH4 Q9XVI0 Q9XVK6 Q9XW53 U4PAK0 X5LX76	C05D9.3 CELE_F22G12.5 CELE_F23H11.4 CELE_F46H5.4 CELE_T04C9.1 CELE_Y105E8A.25 CELE_Y57G11C.1147 PLD aap-1 abi-1 abl-1 aex-4 age-1 cav-1 cav-2 cdc-42 ced-10 ced-5 cgef-1 chin-1 citk-1 citk-2 cyk-1 cyk-4 ect-2 ephx-1 fozi-1 frm-3 gap gcp-2.1 gcp-2.2 gei-1 gex-2 gex-3 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 gpa-12 hum-7 kin-18 let-341 let-99 magu-1 max-2 mrck-1 pac-1 pak-1 pak-2 par-6 pes-7 pix-1 pkn-1 pld-1 rab-7 rac-1 rga-1 rga-2 rga-5 rga-8 rga-9 rhgf-1 rhi-1 ric-4 rlbp-1 snb-1 sos-1 spv-1 srgp-1 sulu syd-1 tag-325 tag-77 tag-81 tiam-1 toe-2 uig-1 unc-112 unc-73 vab-1 vang-1 vav-1 wve-1	Caenorhabditis elegans
RAC3 GTPase cycle	Amino acid transporter Amino acid transporter Arf-GAP domain-containing protein CRAL-TRIO domain-containing protein Cadherin-4 Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Excitatory amino acid transporter GTPase-activating protein pac-1 Glutamate carboxypeptidase 2 homolog MAGUK family Membrane-associated protein gex-3 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphoinositide 3-kinase adapter subunit Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein let-99 Protein unc-112 Protein vav-1 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rac GTPase-activating protein 1 Rap guanine nucleotide exchange factor 1 Ras-related protein Rab-7a Ras-related protein ced-10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 Wiskott-Aldrich syndrome protein family member t-SNARE protein aex-4	A0A0K3AR51 A0A2K5AU23 A5PEW5 A5Z2X2 G5EDP9 G5EEN8 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 H2KZX7 O01443 O01847 O02495 O17590 O18210 O44518 O45611 O61460 O61528 P03949 P34288 P46549 P46941 P55163 P91406 Q03206 Q05062 Q10901 Q10929 Q17850 Q18685 Q18879 Q19319 Q19370 Q19467 Q20496 Q21341 Q21353 Q21751 Q22682 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q95XW5 Q9GYK2 Q9UAY8 Q9XUS9 Q9XVK6	C05D9.3 CELE_F22G12.5 CELE_F23H11.4 CELE_T04C9.1 CELE_Y34B4A.4 CELE_Y57G11C.1147 aap-1 abi-1 abl-1 aex-4 cav-1 cav-2 cdc-42 cdh-4 ced-10 cgef-1 cyk-1 cyk-4 gap gcp-2.1 gcp-2.2 gex-2 gex-3 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 kin-18 let-99 magu-1 max-2 ocrl-1 pac-1 pak-1 pak-2 rab-7 rac-1 rga-1 rga-5 rga-6 rga-8 rhi-1 ric-4 snb-1 srgp-1 sulu syd-1 tag-325 tag-81 tiam-1 toe-2 unc-112 unc-73 vab-1 vang-1 vav-1 wve-1	Caenorhabditis elegans
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Cystinosin homolog Excitatory amino acid transporter Mitochondrial carrier protein PET8 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Vesicular GABA transporter	O18210 P34579 Q09500 Q10901 Q18934 Q21353 Q21751 Q22682 Q9UAY8	ctns-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 slc-25A26 slc-25a26 unc-47	Caenorhabditis elegans
Astrocytic Glutamate-Glutamine Uptake And Metabolism	Amino acid transporter Amino acid transporter Excitatory amino acid transporter Glutamine synthetase Probable glutamine synthetase Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 glutamine synthetase glutamine synthetase glutamine synthetase	O02225 O18210 P34497 Q10901 Q21353 Q21751 Q22682 Q95YD1 Q9U307 Q9UAY8 Q9XVU2	gln-1 gln-2 gln-3 gln-5 gln-6 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7	Caenorhabditis elegans
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Aminopeptidase ltah-1.1 Gamma-glutamyltransferase Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Multidrug resistance-associated protein 1	A0A486WVP7 B5BM47 G5EFT4 H2L030 H2L0B7 O18256 Q3S1M2 Q9N5V4	C53D5.5 CELE_H14N18.4 CELE_T03D8.6 CELE_T19H12.6 CELE_Y7A9A.1 CELE_Y97E10AR.2 ltah-1.1 mrp-1	Caenorhabditis elegans
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase-like protein AC3.5 Aminopeptidase Aminopeptidase Aminopeptidase Aminopeptidase Aminopeptidase Aminopeptidase Aspartic protease 10 Aspartic protease 17 Aspartic protease 1 Aspartic protease 3 Aspartic protease 4 Aspartic protease 6 Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Cathepsin Z-1 Gut esterase 1 Inactive angiotensin-converting enzyme-related protein NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family Neprilysin-11 Neprilysin-1 Neprilysin-21 Neprilysin-2 Neprilysin Neprilysin Neprilysin Neprilysin Neprilysin Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase A1 domain-containing protein Peptidase M13 C-terminal domain-containing protein Peptidase M13 C-terminal domain-containing protein Peptidase M13 N-terminal domain-containing protein Peptidase M14 carboxypeptidase A domain-containing protein Peptidase M14 carboxypeptidase A domain-containing protein Peptidase M14 carboxypeptidase A domain-containing protein Peptidase M14 carboxypeptidase A domain-containing protein Peptidase_M1 domain-containing protein Peptidase_M13 domain-containing protein Peptidase_M13 domain-containing protein Peptidase_M13_N domain-containing protein Puromycin-sensitive aminopeptidase Putative aminopeptidase-2 Putative carboxypeptidase suro-1 SERPIN domain-containing protein SERPIN domain-containing protein Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein ShKT domain-containing protein ShKT domain-containing protein ShKT domain-containing protein Vacuolar H ATPase	A0A131MCS3 A0A1C3NSL8 A0A5S9MNU9 A5A631 A9Z1L1 G3MU29 G5EC01 G5EC13 G5EC96 G5ECY2 G5ED52 G5EDJ7 G5EE40 G5EEI4 G5EFH4 G5EGH4 G5EGP8 H2KYL1 H2KZE5 H2L0K5 H2L0K7 H2L0M5 H9G2Y9 O01302 O01530 O01531 O01532 O16338 O16339 O16607 O16636 O16652 O16789 O16790 O16795 O16796 O17365 O44857 O45072 O45311 O45520 O45569 P55956 P92016 Q04457 Q17405 Q18020 Q18287 Q18581 Q18673 Q19651 Q21266 Q21966 Q22008 Q22317 Q22523 Q22531 Q22763 Q22972 Q23268 Q23427 Q400M1 Q4LDP0 Q4TT88 Q6A577 Q7JKL9 Q86NE0 Q8MQ23 Q8MYN5 Q8MYN6 Q8MYN7 Q94271 Q9BL88 Q9NAA0 Q9TZC6 Q9U2H2 Q9U2T0 Q9U2T1 Q9XTY9 Q9XU75 Q9XVQ1 Q9XVV9 Q9XW75	AC3.5 C28G1.2 CELE_F02D8.4 CELE_F15D3.4 CELE_F41C6.4 CELE_F44G3.7 CELE_F49B2.6 CELE_R03G8.6 CELE_T06A4.1 CELE_T06A4.3 CELE_T12E12.6 CELE_W01A8.6 CELE_Y18H1A.9 CELE_Y42A5A.1 CELE_Y53F4B.20 CELE_Y59C2A.1 CELE_Y67D8C.9 CELE_ZC434.9 T16G12.1 acn-1 anp-1 asp-1 asp-10 asp-12 asp-13 asp-14 asp-15 asp-16 asp-17 asp-18 asp-19 asp-2 asp-3 asp-4 asp-5 asp-6 asp-7 asp-8 asp-9 cest-1 cest-1.1 cest-1.2 cest-12 cest-13 cest-16 cest-17 cest-19 cest-2.1 cest-2.2 cest-2.3 cest-24 cest-26 cpz-1 ges-1 hrg-7 nep-1 nep-10 nep-11 nep-12 nep-13 nep-16 nep-17 nep-18 nep-2 nep-20 nep-21 nep-22 nep-23 nep-24 nep-25 nep-26 nep-3 nep-4 nep-6 nep-8 nep-9 pam-1 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 suro-1 vha-20	Caenorhabditis elegans
Erythrocytes take up carbon dioxide and release oxygen	Ammonium transporter AmtB-like domain-containing protein Anion exchange protein Carbonic anhydrase Putative carbonic anhydrase 3 Putative carbonic anhydrase 5	O02637 Q10462 Q22947 Q27504 Q58QG8	abts-4 cah-3 cah-5 cah-6 rhr-1	Caenorhabditis elegans
Erythrocytes take up oxygen and release carbon dioxide	Ammonium transporter AmtB-like domain-containing protein Anion exchange protein Carbonic anhydrase Putative carbonic anhydrase 3 Putative carbonic anhydrase 5	O02637 Q10462 Q22947 Q27504 Q58QG8	abts-4 cah-3 cah-5 cah-6 rhr-1	Caenorhabditis elegans
Regulation of IGF Activity by IGFBP	Amyloid-beta-like protein Anoctamin Apolipoprotein L, 1 Apolipoprotein L3-like BMP-like protein unc-129 Calumenin-like protein Cystatin cpi-2 DUF19 domain-containing protein Dauer larva development regulatory growth factor daf-7 Disintegrin and metalloproteinase domain-containing protein 10 homolog EGL-17 Endoplasmin homolog Extracellular serine/threonine protein kinase CeFam20 Fibronectin type-III domain-containing protein Galectin domain-containing protein Glucosidase 2 subunit beta J domain-containing protein Multiple epidermal growth factor-like domains protein 6 NTR domain-containing protein NUCleoBindin homolog Nidogen PNPLA domain-containing protein PNPLA domain-containing protein Patanin-like phospholipase domain-containing protein atgl-1 Probable syndecan Protein dbl-1 Protein disulfide-isomerase 1 Protein disulfide-isomerase 2 Protein disulfide-isomerase A6 homolog Putative alpha-L-fucosidase Putative metalloproteinase inhibitor tag-225 SERPIN domain-containing protein SERPIN domain-containing protein SPARC Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Sulfhydryl oxidase Thioredoxin domain-containing protein Transmembrane protein 132 homolog VWFA domain-containing protein	A9Z1L1 G5EBH7 G5EBY8 G5EC87 G5ECM9 G5ECY2 G5EE40 G5EEF1 G5EEL5 G5EFD9 G5EFH4 G5EFX3 H2FLL2 H2KZY5 H2L2L3 O17365 O45520 P34714 P49713 P50605 P91189 P92172 Q09EE8 Q10651 Q11067 Q11186 Q17770 Q17967 Q18048 Q18096 Q18287 Q18948 Q19651 Q20684 Q21265 Q21267 Q22235 Q8MQ51 Q8WQF7 Q8WQF8 Q93791 Q9BL47 Q9N5Z7 Q9XTW2 Q9XVQ1	B0524.2 C16E9.1 C18E9.7 C28G1.2 CELE_D1054.1 CELE_F07F6.7 CELE_F07F6.8 CELE_F15D3.4 CELE_F44G3.7 CELE_F47B7.2 CELE_M04D5.1 CELE_W01A8.8 CELE_Y64G10A.7 CELE_ZK1307.8 W03G11.3 Y71H2AM.10 anoh-2 apl-1 atgl-1 calu-1 cet-1 cpi-2 daf-7 dbl-1 dnj-7 egl-17 enpl-1 famk-1 lec-2 nid-1 nucb-1 ost-1 pdi-1 pdi-2 pdi-6 sdn-1 sparc srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 sup-17 tag-225 tag-320 timp-1 unc-129	Caenorhabditis elegans
Post-translational protein phosphorylation	Amyloid-beta-like protein Anoctamin Apolipoprotein L, 1 Apolipoprotein L3-like BMP-like protein unc-129 Calumenin-like protein Cystatin cpi-2 DUF19 domain-containing protein Dauer larva development regulatory growth factor daf-7 Disintegrin and metalloproteinase domain-containing protein 10 homolog EGL-17 Endoplasmin homolog Extracellular serine/threonine protein kinase CeFam20 Fibronectin type-III domain-containing protein Galectin domain-containing protein Glucosidase 2 subunit beta J domain-containing protein Multiple epidermal growth factor-like domains protein 6 NTR domain-containing protein NUCleoBindin homolog Nidogen PNPLA domain-containing protein PNPLA domain-containing protein Patanin-like phospholipase domain-containing protein atgl-1 Probable syndecan Protein dbl-1 Protein disulfide-isomerase 1 Protein disulfide-isomerase 2 Protein disulfide-isomerase A6 homolog Putative alpha-L-fucosidase Putative metalloproteinase inhibitor tag-225 SERPIN domain-containing protein SERPIN domain-containing protein SPARC Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Sulfhydryl oxidase Thioredoxin domain-containing protein Transmembrane protein 132 homolog VWFA domain-containing protein	A9Z1L1 G5EBH7 G5EBY8 G5EC87 G5ECM9 G5ECY2 G5EE40 G5EEF1 G5EEL5 G5EFD9 G5EFH4 G5EFX3 H2FLL2 H2KZY5 H2L2L3 O17365 O45520 P34714 P49713 P50605 P91189 P92172 Q09EE8 Q10651 Q11067 Q11186 Q17770 Q17967 Q18048 Q18096 Q18287 Q18948 Q19651 Q20684 Q21265 Q21267 Q22235 Q8MQ51 Q8WQF7 Q8WQF8 Q93791 Q9BL47 Q9N5Z7 Q9XTW2 Q9XVQ1	B0524.2 C16E9.1 C18E9.7 C28G1.2 CELE_D1054.1 CELE_F07F6.7 CELE_F07F6.8 CELE_F15D3.4 CELE_F44G3.7 CELE_F47B7.2 CELE_M04D5.1 CELE_W01A8.8 CELE_Y64G10A.7 CELE_ZK1307.8 W03G11.3 Y71H2AM.10 anoh-2 apl-1 atgl-1 calu-1 cet-1 cpi-2 daf-7 dbl-1 dnj-7 egl-17 enpl-1 famk-1 lec-2 nid-1 nucb-1 ost-1 pdi-1 pdi-2 pdi-6 sdn-1 sparc srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 sup-17 tag-225 tag-320 timp-1 unc-129	Caenorhabditis elegans
RHOB GTPase cycle	Anillin-like protein 2 Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 CRAL-TRIO domain-containing protein Cadherin domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 DH domain-containing protein DH domain-containing protein FH2 domain-containing protein FH2 domain-containing protein Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphoinositide 3-kinase adapter subunit Probable rho GDP-dissociation inhibitor Protein ECT2 Protein kinase domain-containing protein Protein let-99 Protein vav-1 Rac GTPase-activating protein 1 Ras-like GTP-binding protein rhoA Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho guanine nucleotide exchange factor osg-1 Rho-GAP domain-containing protein Rho-associated protein kinase let-502 SH2 domain-containing protein START domain-containing protein Stomatin-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tight junction protein ZO-1 Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A4V0IKG6 A0A4V0ILM7 A5PEW5 D6VPA1 F0IWT2 G5EDP9 G5EEN8 G5EFE1 H2KY90 H2KYI7 H2KZH5 H2KZV6 O02495 O17772 O44326 O45611 O61528 P91406 P92199 Q09994 Q10953 Q17777 Q18825 Q18879 Q19479 Q19958 Q20440 Q20496 Q21341 Q21653 Q22038 Q23130 Q45FX5 Q5F4U0 Q7JP75 Q8I103 Q93332 Q94051 Q965J0 Q9U364 Q9XUS9	C07B5.4 CELE_T04C9.1 CELE_Y105E8A.25 aap-1 aex-4 ani-2 bar-1 cav-1 cav-2 cdh-10 cgef-1 cyk-1 cyk-4 daam-1 ect-2 ephx-1 gck-4 gcp-2.1 gcp-2.2 gei-1 hmp-2 hum-7 inft-2 let-502 let-99 osg-1 pes-7 pkn-1 pvl-1 rga-1 rga-5 rhgf-1 rhi-1 rho-1 rhoa ric-4 snb-1 spy-1 sto-2 tag-81 toe-2 unc-73 vang-1 vav-1 wrm-1 zoo-1	Caenorhabditis elegans
Bicarbonate transporters	Anion exchange protein Anion exchange protein	B3WFV9 Q58QG8	abts-1 abts-4	Caenorhabditis elegans
Postmitotic nuclear pore complex (NPC) reformation	Apple domain-containing protein GTP-binding nuclear protein ran-1 Nuclear Pore complex Protein Nuclear pore complex protein 15 Nuclear pore complex protein 5 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup98-Nup96 Nucleoporin SEH1 Protein SEC13 homolog Ran GTPase-activating protein 2 Regulator of chromosome condensation SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier WD_REPEATS_REGION domain-containing protein	G5ECB4 G5EEH9 O17915 O45933 P34342 P34343 P55853 Q17872 Q18211 Q19131 Q22078 Q8T8M4 Q95017 Q9N4A7	CeSec13R npp-10 npp-15 npp-18 npp-2 npp-20 npp-23 npp-5 npp-6 nup133 ran-1 ran-2 ran-3 sec-13 smo-1 smt3 srap-1 sumo ubc-9	Caenorhabditis elegans
RAC2 GTPase cycle	Arf-GAP domain-containing protein Armadillo repeat-containing domain-containing protein CED-5 CRAL-TRIO domain-containing protein Cadherin-4 Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Glutamate carboxypeptidase 2 homolog MAGUK family Membrane-associated protein gex-3 Metaxin-1 homolog N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein let-99 Protein vav-1 Rac GTPase-activating protein 1 Ras-related protein Rab-18 Ras-related protein Rab-7a Ras-related protein ced-10 Ras-related protein rac-2 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein SAM50-like protein gop-3 SH3 domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Target of ERK kinase mpk-1 Uncharacterized integrin beta-like protein C05D9.3 Vang-like protein WAPL domain-containing protein Wiskott-Aldrich syndrome protein family member	A0A0K3AR51 A0A2K5AU23 A5Z2X2 G5EDP9 G5EDU3 G5EEN3 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV6 O01847 O02495 O17772 O44518 O45503 O45611 O61460 O61528 P46549 P46576 P55163 P91406 Q03206 Q05062 Q10929 Q17850 Q18879 Q19319 Q19467 Q20496 Q21341 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q94124 Q94125 Q95XW5 Q9BL44 Q9GYK2 Q9U1V2 Q9XUS9 Q9XVK6	C05D9.3 CELE_F22G12.5 CELE_T04C9.1 CELE_Y57G11C.1147 CELE_Y67A10A.7 CELE_Y71H2AM.12 PLD aap-1 abi-1 age-1 cav-1 cav-2 cdc-42 cdh-4 ced-10 ced-5 cgef-1 cyk-1 cyk-4 gcp-2.1 gcp-2.2 gex-2 gex-3 git-1 gop-3 kin-18 let-99 magu-1 max-2 mtx-1 pak-1 pak-2 pes-7 pld-1 rab-7 rac-1 rac-2 rga-1 rga-5 rga-8 rhi-1 snb-1 sulu syd-1 tiam-1 toe-2 unc-73 vab-1 vang-1 vav-1 wve-1	Caenorhabditis elegans
RHOU GTPase cycle	Arf-GAP domain-containing protein CHp/Wrch Rho-like protein homolog Calponin-homology (CH) domain-containing protein Cell division control protein 42 homolog E3 ubiquitin-protein ligase wwp-1 Ephrin receptor 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Inactive tyrosine-protein kinase kin-32 Intersectin-1 Microtubule-actin cross-linking factor 1 Myosin motor domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family PDZ domain-containing protein Partitioning defective protein 6 Phosphoinositide 3-kinase adapter subunit Probable clathrin heavy chain 1 Protein let-99 Rho-GAP domain-containing protein SH2 domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Sex muscle abnormal protein 5 Signal transducing adapter molecule 1 Spectrin alpha chain Spectrin beta chain Target of ERK kinase mpk-1 Thioredoxin-like protein UBA domain-containing protein Vang-like protein	A0A0K3AS36 A0A1N7SYP3 E0AHA7 G5EDP9 G5EES9 G5EFU0 G5EG81 G5EGQ3 H2KY90 H2KZH5 O01498 O17772 O61460 P29355 P34574 Q05062 Q17796 Q17850 Q19370 Q19467 Q19739 Q20398 Q21341 Q21408 Q21430 Q95PX0 Q95XA9 Q95YD4 Q9N2Z7 Q9NAN2 U4PBY2	CELE_T24B8.7 aap-1 cdc-42 chc-1 chw-1 gap-3 git-1 hgrs-1 hum-8 itsn-1 kin-32 let-99 magu-4 max-2 nck-1 pak-1 pak-2 par-6 pes-7 pix-1 pqn-19 sem-5 spc-1 srgp-1 stam-1 toe-2 txl txl-1 unc-70 vab-1 vab-10 vang-1 wwp-1	Caenorhabditis elegans
RHOV GTPase cycle	Arf-GAP domain-containing protein CHp/Wrch Rho-like protein homolog Calponin-homology (CH) domain-containing protein Cell division control protein 42 homolog Ephrin receptor 1 GTPase-activating protein pac-1 Microtubule-actin cross-linking factor 1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family PDZ domain-containing protein Partitioning defective protein 6 Phosphoinositide 3-kinase adapter subunit Probable clathrin heavy chain 1 Protein kinase domain-containing protein Protein let-99 SH2 domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Spectrin alpha chain Spectrin beta chain Target of ERK kinase mpk-1 Thioredoxin-like protein Tropomyosin isoforms a/b/d/f UBA domain-containing protein Uncharacterized protein C09G1.4 Unconventional myosin-IXa-like Vang-like protein WW domain-containing protein tag-325	A0A1N7SYP3 E0AHA7 F0IWT2 G5EDP9 G5EES9 G5EFU0 G5EG81 G5EGQ3 H2KY90 H2KZH5 O17772 O61460 P34288 P34574 P46941 Q05062 Q17850 Q17865 Q19467 Q19739 Q20398 Q21341 Q21408 Q21430 Q22866 Q95PX0 Q95XA9 Q9NAC7 Q9NAN2	C09G1.4 CELE_T24B8.7 CELE_Y53F4B.1 aap-1 cdc-42 chc-1 chw-1 gap gap-3 git-1 hum-7 let-99 lev-11 magu-4 max-2 nck-1 pac-1 pak-1 pak-2 par-6 pes-7 pix-1 spc-1 tag-325 tmy-1 toe-2 txl txl-1 unc-70 vab-1 vab-10 vang-1	Caenorhabditis elegans
Ephrin signaling	Arf-GAP domain-containing protein Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin receptor 1 Ephrin-4 Myosin regulatory light chain NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Ras-related protein ced-10 SH2 domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Tyrosine protein-kinase src-1	G5EE56 G5EEE7 G5EGQ3 O44516 O61460 Q03206 Q09510 Q17850 Q19467 Q19475 Q21430 Q95PX0 Q95XA9 Q9U3M2	ced-10 efn-2 efn-3 efn-4 gap-3 git-1 mab-26 max-2 mlc-4 nck-1 pak-1 pix-1 rac-1 src-1 vab-1 vab-2	Caenorhabditis elegans

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