GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 176 - 200 of 499 in total
Pathway Name Protein Name UniProt ID Gene Symbol ▲ Organism GlyTouCan ID
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
  • C52E4.5
  • mans-1
Caenorhabditis elegans
Synthesis of Leukotrienes (LT) and Eoxins (EX)
  • C53D5.5
  • CELE_H14N18.4
  • CELE_T03D8.6
  • CELE_T19H12.6
  • CELE_Y7A9A.1
  • CELE_Y97E10AR.2
  • ltah-1.1
  • mrp-1
Caenorhabditis elegans
Glycogen synthesis
  • CC8.2
  • CELE_R05F9.6
  • CELE_T04A8.7
  • CELE_T10B10.8
  • gsy-1
  • gyg-1
  • gyg-2
  • rml-1
Caenorhabditis elegans
Synthesis of IP3 and IP4 in the cytosol
  • CELE_E04F6.4
  • CELE_T05C3.6
  • CELE_Y51A2D.13
  • F09G2.8
  • cal-5
  • daf-18
  • egl-8
  • inpp-1
  • lfe-2
  • ocrl-1
  • plc-1
  • plc-3
  • plc-4
  • unc-26
Caenorhabditis elegans
Pentose phosphate pathway
  • CELE_F07A11.5
  • CELE_F08F8.7
  • CELE_Y43F4B.5
  • F09E5.3
  • T25B9.9
  • Y57G11C.3
  • gspd-1
  • rpia-1
  • shpk-1
  • tald-1
  • tkt-1
Caenorhabditis elegans
O-glycosylation of TSR domain-containing proteins
  • CELE_F09F9.4
  • CELE_F11C7.2
  • CELE_T21B6.3
  • CELE_ZC250.2
  • gon-1
  • pad-2
  • sbsp-1
  • spon-1
Caenorhabditis elegans
RET signaling
  • CELE_F09G2.1
  • CELE_Y69A2AR.31
Caenorhabditis elegans
PI3K/AKT Signaling
  • CELE_F11E6.8
  • CELE_F14B4.1
  • CELE_F59F5.3
  • CELE_T22A3.6
  • CELE_W04B5.5
  • CELE_Y71H2AM.12
  • CeTor
  • aap-1
  • age-1
  • akt-1
  • akt-2
  • cash-1
  • ced-10
  • ddr-2
  • egl-15
  • egl-17
  • kin-36
  • kin-7
  • klo-1
  • klo-2
  • let-23
  • let-363
  • let-756
  • mlst-8
  • nipi-3
  • pvf-1
  • rac-1
  • rac-2
  • rict-1
  • rme-2
  • sem-5
  • sgk-1
  • sinh-1
  • src-1
  • svh-2
  • svh-4
Caenorhabditis elegans
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • CELE_F11E6.8
  • CELE_F14B4.1
  • CELE_F59F5.3
  • CELE_T22A3.6
  • CELE_Y71H2AM.12
  • aap-1
  • age-1
  • akt-1
  • akt-2
  • cash-1
  • ced-10
  • ddr-2
  • egl-15
  • egl-17
  • kin-36
  • kin-7
  • klo-1
  • klo-2
  • let-23
  • let-756
  • let-92
  • paa-1
  • ppk-1
  • ppk-2
  • pptr-1
  • pptr-2
  • pvf-1
  • rac-1
  • rac-2
  • rme-2
  • sem-5
  • src-1
  • svh-2
  • svh-4
Caenorhabditis elegans
Negative regulation of MET activity
  • CELE_F11E6.8
  • CELE_F20H11.4
  • CELE_M04G7.2
  • CELE_T13H5.1
  • CELE_T22A3.6
  • CELE_T28F4.3
  • CELE_Y71G12B.31
  • CELE_ZK616.65
  • cdap-2
  • dep-1
  • eak-5
  • eak-6
  • ehs-1
  • hgrs-1
  • pqn-19
  • sdf-9
  • sem-5
  • sli-1
  • sma-10
  • stam-1
  • svh-2
  • ubia
  • ubib
  • ubl-1
  • ubq-1
  • ubq-2
  • unc-57
Caenorhabditis elegans
MET activates RAP1 and RAC1
  • CELE_F11E6.8
  • CELE_F46H5.4
  • CELE_T22A3.6
  • CELE_Y34B4A.4
  • ced-10
  • ced-2
  • rac-1
  • rap-1
  • sem-5
  • svh-2
Caenorhabditis elegans
MET activates STAT3
  • CELE_F11E6.8
  • CELE_T12G3.2
  • CELE_T22A3.6
  • sta-1
  • sta-2
  • stat-b
  • svh-2
Caenorhabditis elegans
MET activates PI3K/AKT signaling
  • CELE_F11E6.8
  • CELE_T22A3.6
  • aap-1
  • age-1
  • sem-5
  • svh-2
Caenorhabditis elegans
MET receptor recycling
  • CELE_F11E6.8
  • CELE_T22A3.6
  • apt-9
  • arf-6
  • ced-2
  • sem-5
  • svh-2
Caenorhabditis elegans
MET activates RAS signaling
  • CELE_F11E6.8
  • CELE_T22A3.6
  • let-341
  • let-60
  • lin-34
  • sem-5
  • sos-1
  • svh-2
Caenorhabditis elegans
MET Receptor Activation
  • CELE_F11E6.8
  • CELE_T22A3.6
  • svh-2
Caenorhabditis elegans
Signaling by MST1
  • CELE_F11E6.8
  • CELE_T22A3.6
  • svh-2
Caenorhabditis elegans
Drug-mediated inhibition of MET activation
  • CELE_F11E6.8
  • CELE_T22A3.6
  • svh-2
Caenorhabditis elegans
Sema4D mediated inhibition of cell attachment and migration
  • CELE_F11E6.8
  • R-ras1
  • ced-10
  • mab-20
  • plx-2
  • rac-1
  • ras-1
  • ras1
  • rga-5
  • rho-1
  • rhoa
  • sema-1a
  • smp-1
  • smp-2
  • svh-2
Caenorhabditis elegans
HSF1-dependent transactivation
  • CELE_F11F1.1
  • CeTor
  • daf-15
  • daf-21
  • hsb-1
  • hsf-1
  • hsp-1
  • hsp-12.2
  • hsp12-2
  • hsp70a
  • let-363
  • mlst-8
  • unc-43
Caenorhabditis elegans
HSP90 chaperone cycle for SHRs
  • CELE_F11F1.1
  • daf-21
  • dnj-12
  • dnj-19
  • hsp-1
  • hsp70a
  • sti-1
Caenorhabditis elegans
TRP channels
  • CELE_F13B12.3
  • ced-11
  • cup-5
  • gon-2
  • gtl-1
  • gtl-2
  • ocr-1
  • ocr-2
  • ocr-3
  • ocr-4
  • strpc1
  • trp-1
  • trp-2
  • trpl-2
Caenorhabditis elegans
Cargo recognition for clathrin-mediated endocytosis
  • CELE_F14B4.1
  • CELE_F49C12.9
  • CELE_T27E4.1
  • ap50
  • apa-2
  • apb-1
  • aps-2
  • apt-10
  • arr-1
  • cdap-2
  • chc-1
  • clic-1
  • csn-1
  • csn-2
  • csn-3
  • csn-4
  • csn-5
  • csn-6
  • cwn-2
  • dpy-23
  • dsh-1
  • dsh-2
  • ehs-1
  • epn-1
  • fcho-1
  • gar-3
  • hgrs-1
  • itsn-1
  • kin-7
  • let-23
  • lin-17
  • mig-5
  • mrp-6
  • ncap-1
  • ned-8
  • npr-25
  • ooc-5
  • pqn-19
  • rme-2
  • scav-3
  • sem-5
  • sli-1
  • snb-1
  • snb-2
  • snb-5
  • snb-6
  • snb-7
  • snt-1
  • snt-2
  • snt-4
  • snt-5
  • stam-1
  • sue-1
  • tkr-1
  • tor-1
  • tor-2
  • ubia
  • ubib
  • ubl-1
  • ubq-1
  • ubq-2
  • ubql-1
  • unc-11
  • unc-17
  • unc-41
  • unc-57
  • vamp-7
  • wnt-2
Caenorhabditis elegans
Clathrin-mediated endocytosis
  • CELE_F14B4.1
  • CELE_T27E4.1
  • amph-1
  • ap50
  • apa-2
  • apb-1
  • aps-2
  • apt-10
  • arp-2
  • arr-1
  • arx-1
  • arx-2
  • arx-3
  • arx-4
  • arx-5
  • arx-6
  • arx-7
  • cdap-2
  • chc-1
  • clic-1
  • cwn-2
  • dnj-25
  • dpy-23
  • dsh-1
  • dsh-2
  • dyn-1
  • ehs-1
  • epn-1
  • fcho-1
  • gar-3
  • hgrs-1
  • hipr-1
  • hsp-1
  • hsp70a
  • itsn-1
  • kin-7
  • let-23
  • lin-17
  • lst-4
  • mig-5
  • mrp-6
  • ncap-1
  • npr-25
  • ocrl-1
  • ppk-1
  • pqn-19
  • rab-5
  • rme-2
  • rme-6
  • scav-3
  • sdpn-1
  • sem-5
  • sli-1
  • snb-1
  • snb-2
  • snb-5
  • snb-6
  • snb-7
  • snt-1
  • snt-2
  • snt-4
  • snt-5
  • stam-1
  • sue-1
  • tkr-1
  • toca-1
  • toca-2
  • ubia
  • ubib
  • ubl-1
  • ubq-1
  • ubq-2
  • unc-11
  • unc-17
  • unc-26
  • unc-41
  • unc-57
  • vamp-7
  • wnt-2
Caenorhabditis elegans
Signaling by EGFR
  • CELE_F14B4.1
  • CELE_Y111B2A.12
  • kin-7
  • let-23
  • rme-2
  • sma-10
  • src-1
Caenorhabditis elegans

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024