GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **426 - 450** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Pyrimidine biosynthesis	Dihydroorotate dehydrogenase (quinone), mitochondrial Multifunctional protein CAD Uridine 5'-monophosphate synthase	P11172 P27708 Q02127	CAD DHODH UMPS	Homo sapiens (human)
Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS)	Solute carrier family 2, facilitated glucose transporter member 2	P11168	GLUT2 SLC2A2	Homo sapiens (human)	G58161NS G93924TT
Intestinal hexose absorption	Regulatory solute carrier protein family 1 member 1 Sodium/glucose cotransporter 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 5	P11168 P13866 P22732 Q92681	GLUT2 GLUT5 NAGT RSC1A1 SGLT1 SLC2A2 SLC2A5 SLC5A1	Homo sapiens (human)	G58161NS G93924TT
Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1)	Solute carrier family 2, facilitated glucose transporter member 1	P11166	GLUT1 SLC2A1	Homo sapiens (human)	G58161NS
ATF6 (ATF6-alpha) activates chaperone genes	Calreticulin Cyclic AMP-dependent transcription factor ATF-4 Cyclic AMP-dependent transcription factor ATF-6 alpha DNA damage-inducible transcript 3 protein Endoplasmic reticulum chaperone BiP Endoplasmin Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma	P11021 P14625 P18848 P18850 P23511 P25208 P27797 P35638 Q13952	ATF4 ATF6 CALR CHOP CHOP10 CREB2 CRTC DDIT3 GADD153 GRP78 GRP94 HAP3 HSP90B1 HSPA5 HSPC4 NFYA NFYB NFYC TRA1 TXREB	Homo sapiens (human)
Toxicity of botulinum toxin type B (botB)	Botulinum neurotoxin type B HA-17 HA-33 protein Ha70 protein NTNHA Synaptotagmin-1 Synaptotagmin-2 Vesicle-associated membrane protein 2	P10844 P21579 P63027 Q45877 Q45878 Q57230 Q8N9I0 Q9LBS8	HA HA-17 HA-33 SVP65 SYB2 SYT SYT1 SYT2 VAMP2 botB ha17 ha34 ha70 ntnha	Homo sapiens (human)
Dasatinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Nilotinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Imatinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Sunitinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Signaling by kinase domain mutants of KIT	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Signaling by extracellular domain mutants of KIT	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Regorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Sorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Masitinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Signaling by juxtamembrane domain KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
KIT mutants bind TKIs	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Miscellaneous substrates	Cytochrome P450 2D6 Cytochrome P450 2S1 Cytochrome P450 2U1 Cytochrome P450 2W1 Cytochrome P450 3A43 Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F2 Cytochrome P450 4F3 Ultra-long-chain fatty acid omega-hydroxylase	P10635 P13584 P78329 Q02928 Q08477 Q5TCH4 Q6NT55 Q7Z449 Q8TAV3 Q96SQ9 Q9HB55 Q9HBI6	CYP2D6 CYP2DL1 CYP2S1 CYP2U1 CYP2W1 CYP3A43 CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F2 CYP4F22 CYP4F3 LTB4H	Homo sapiens (human)
Fatty acids	Cytochrome P450 2A13 Cytochrome P450 2A7 Cytochrome P450 2B6 Cytochrome P450 2D6 Cytochrome P450 2F1 Cytochrome P450 2J2 Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F12 Cytochrome P450 4F2 Cytochrome P450 4F3 Cytochrome P450 4F8 Ultra-long-chain fatty acid omega-hydroxylase	P10635 P13584 P20813 P20853 P24903 P51589 P78329 P98187 Q02928 Q08477 Q16696 Q5TCH4 Q6NT55 Q9HBI6 Q9HCS2	CYP2A13 CYP2A7 CYP2B6 CYP2D6 CYP2DL1 CYP2F1 CYP2J2 CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F12 CYP4F2 CYP4F22 CYP4F3 CYP4F8 LTB4H	Homo sapiens (human)
Defective NEU1 causes sialidosis	Beta-galactosidase Lysosomal protective protein Sialidase-1	P10619 P16278 Q99519	CTSA ELNR1 GLB1 NANH NEU1 PPGB	Homo sapiens (human)
Protein repair	Methionine-R-sulfoxide reductase B1 Methionine-R-sulfoxide reductase B2, mitochondrial Methionine-R-sulfoxide reductase B3 Mitochondrial peptide methionine sulfoxide reductase Protein-L-isoaspartate(D-aspartate) O-methyltransferase Thioredoxin	P10599 P22061 Q8IXL7 Q9NZV6 Q9UJ68 Q9Y3D2	CBS-1 MSRA MSRB MSRB1 MSRB2 MSRB3 PCMT1 SEPX1 TRDX TRX TRX1 TXN	Homo sapiens (human)
RUNX3 Regulates Immune Response and Cell Migration	Core-binding factor subunit beta Integrin alpha-4 Integrin alpha-L Osteopontin Runt-related transcription factor 3	P10451 P13612 P20701 Q13761 Q13951	AML2 BNSP CBFA3 CBFB CD11A CD49D ITGA4 ITGAL OPN PEBP2A3 RUNX3 SPP1	Homo sapiens (human)
Activation of BAD and translocation to mitochondria	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta Apoptosis regulator Bcl-2 BH3-interacting domain death agonist Bcl2-associated agonist of cell death Calcineurin subunit B type 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform	P10415 P27348 P31749 P31751 P31946 P31947 P48454 P55957 P61981 P62258 P63098 P63104 Q04917 Q92934 Q9Y243	AKT1 AKT2 AKT3 BAD BBC6 BCL2 BCL2L8 BID CALNA3 CNA2 CNA3 CNB HME1 PKB PKBG PPP3CC PPP3R1 RAC SFN YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	Homo sapiens (human)
Regulation of MITF-M-dependent genes involved in apoptosis	Adenosine 5'-monophosphoramidase HINT1 Apoptosis regulator Bcl-2 Baculoviral IAP repeat-containing protein 7 Bcl-2-related protein A1 Endoribonuclease Dicer Helicase MOV-10 Histone deacetylase 1 POU domain, class 3, transcription factor 2 Paired amphipathic helix protein Sin3a Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Transient receptor potential cation channel subfamily M member 1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	P10415 P20265 P49773 Q13547 Q16548 Q7Z4N2 Q8NDV7 Q96CA5 Q96ST3 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9 Q9UPY3	AGO1 AGO2 AGO3 AGO4 BCL2 BCL2A1 BCL2L5 BFL1 BIRC7 BRN2 CAGH26 DICER DICER1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 GRS HBPA1 HDAC1 HERNA HINT HINT1 KIAA0928 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAP LIVIN LTRPC1 MLIAP MLSN MLSN1 MOV10 OCT7 OTF7 PKCI1 POU3F2 PRKCNH1 RNF50 RPD3L1 SIN3A TNRC6 TNRC6A TNRC6B TNRC6C TRPM1	Homo sapiens (human)
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen Izumo sperm-egg fusion protein 1 Izumo sperm-egg fusion protein 2 Izumo sperm-egg fusion protein 3 Izumo sperm-egg fusion protein 4	P10323 P21926 Q1ZYL8 Q5VZ72 Q6UXV1 Q8IYV9	ACR ACRS C19orf36 C19orf41 C9orf134 CD9 IZUMO1 IZUMO2 IZUMO3 IZUMO4 MIC3 SCRL TSPAN29	Homo sapiens (human)

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