GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1326 - 1350** of **2090** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
E2F-enabled inhibition of pre-replication complex formation	Cyclin-dependent kinase 1 DNA helicase MCM8 G2/mitotic-specific cyclin-B1 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6	O43913 O43929 P06493 P14635 Q13415 Q13416 Q9UBD5 Q9UJA3 Q9Y5N6	C20orf154 CCNB CCNB1 CDC2 CDC28A CDK1 CDKN1 LATHEO MCM8 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L P34CDC2 PARC1	Homo sapiens (human)
MAPK3 (ERK1) activation	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 Interleukin-6 receptor subunit alpha Interleukin-6 Mitogen-activated protein kinase 3 Non-receptor tyrosine-protein kinase TYK2 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O60674 P05231 P06493 P08887 P23458 P27361 P29597 Q02750 Q06124	CDC2 CDC28A CDK1 CDKN1 ERK1 IFNB2 IL6 IL6R JAK1 JAK1A JAK1B JAK2 MAP2K1 MAPK3 MEK1 P34CDC2 PRKM3 PRKMK1 PTP2C PTPN11 SHPTP2 TYK2	Homo sapiens (human)
Golgi Cisternae Pericentriolar Stack Reorganization	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 General vesicular transport factor p115 Golgi reassembly-stacking protein 1 Golgi reassembly-stacking protein 2 Golgin subfamily A member 2 Golgin-45 Mitogen-activated protein kinase 1 Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-2A Serine/threonine-protein kinase PLK1	O60763 O95067 P06493 P14635 P28482 P53350 P61019 P62820 Q08379 Q9BQQ3 Q9H0U4 Q9H2G9 Q9H8Y8	BLZF1 CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 ERK2 GOLGA2 GOLPH5 GOLPH6 GORASP1 GORASP2 GRASP65 JEM1 MAPK1 P34CDC2 PLK PLK1 PRKM1 PRKM2 RAB1 RAB1A RAB1B RAB2 RAB2A USO1 VDP	Homo sapiens (human)
G2/M DNA replication checkpoint	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Wee1-like protein kinase	O95067 P06493 P14635 P30291 Q99640	CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 MYT1 P34CDC2 PKMYT1 WEE1	Homo sapiens (human)
Activation of NIMA Kinases NEK9, NEK6, NEK7	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Serine/threonine-protein kinase Nek6 Serine/threonine-protein kinase Nek7 Serine/threonine-protein kinase Nek9 Serine/threonine-protein kinase PLK1	O95067 P06493 P14635 P53350 Q8TD19 Q8TDX7 Q9HC98	CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 KIAA1995 NEK6 NEK7 NEK8 NEK9 NERCC P34CDC2 PLK PLK1	Homo sapiens (human)
Mitotic Prophase	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Nuclear mitotic apparatus protein 1	P06493 P14635 Q14980	CCNB CCNB1 CDC2 CDC28A CDK1 CDKN1 NMP22 NUMA NUMA1 P34CDC2	Homo sapiens (human)
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 1C G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Retinoblastoma-associated protein Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3	O00716 O96020 P06400 P11802 P24385 P24864 P24941 P30279 P30281 P38936 P46527 P49918 Q00534 Q01094 Q14186 Q14188 Q14209	BCL1 CAP20 CCND1 CCND2 CCND3 CCNE CCNE1 CCNE2 CDK2 CDK4 CDK6 CDKN1 CDKN1A CDKN1B CDKN1C CDKN2 CDKN6 CIP1 DP1 DP2 E2F1 E2F2 E2F3 KIAA0075 KIP1 KIP2 MDA6 PIC1 PRAD1 RB1 RBBP3 SDI1 TFDP1 TFDP2 WAF1 p27	Homo sapiens (human)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Protein-tyrosine kinase 6	P11802 P24385 P24864 P24941 P46527 Q13882	BCL1 BRK CCND1 CCNE CCNE1 CDK2 CDK4 CDKN1B CDKN2 KIP1 PRAD1 PTK6 p27	Homo sapiens (human)
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	Cyclin-dependent kinase 2 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Retinoblastoma-associated protein	O96020 P06400 P24864 P24941	CCNE CCNE1 CCNE2 CDK2 CDKN2 RB1	Homo sapiens (human)
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Drug-mediated inhibition of CDK4/CDK6 activity	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3	P11802 P24385 P30279 P30281 Q00534	BCL1 CCND1 CCND2 CCND3 CDK4 CDK6 CDKN6 PRAD1	Homo sapiens (human)
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4	Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 2A	P11802 P42771	CDK4 CDKN2 CDKN2A MTS1	Homo sapiens (human)
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4	Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 2A	P11802 P42771	CDK4 CDKN2 CDKN2A MTS1	Homo sapiens (human)
CRMPs in Sema3A signaling	Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 Dihydropyrimidinase-related protein 1 Dihydropyrimidinase-related protein 2 Dihydropyrimidinase-related protein 3 Dihydropyrimidinase-related protein 4 Dihydropyrimidinase-related protein 5 Glycogen synthase kinase-3 beta Neuropilin-1 Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Semaphorin-3A Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14531 O14786 O75051 P06241 P07332 P49841 P51805 Q00535 Q14194 Q14195 Q14563 Q15078 Q16555 Q9BPU6 Q9HCM2 Q9UIW2	CDK5 CDK5R CDK5R1 CDKN5 CRMP1 CRMP2 CRMP3 CRMP4 CRMP5 DPYSL1 DPYSL2 DPYSL3 DPYSL4 DPYSL5 DRP3 FES FPS FYN GSK3B KIAA0463 KIAA1550 NCK5A NOV NRP NRP1 OCT PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B PSSALRE SEMA3A SEMAD SEX ULIP ULIP1 ULIP2 ULIP3 ULIP4 ULIP6 VEGF165R	Homo sapiens (human)
Signaling by FLT3 fusion proteins	Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 GTPase HRas GTPase NRas Golgin subfamily B member 1 NADPH oxidase 4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Spectrin beta chain, non-erythrocytic 1 Thyroid receptor-interacting protein 11 Transcription factor ETV6 Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	P01111 P01112 P11309 P27986 P38936 P41212 P42229 P42336 P51692 Q01082 Q07889 Q14789 Q15643 Q92614 Q9NPH5 Q9UBW7 Q9UQC2	CAP20 CD245 CDKN1 CDKN1A CEV14 CIP1 ETV6 FIM GAB2 GOLGB1 GRB1 HRAS HRAS1 KIAA0216 KIAA0571 MDA6 MYO18A MYSPDZ NOX4 NRAS PIC1 PIK3CA PIK3R1 PIM1 RAMP RENOX SDI1 SOS1 SPTB2 SPTBN1 STAT5 STAT5A STAT5B TEL TEL1 TIAF1 TRIP11 WAF1 ZMYM2 ZNF198	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Cyclin-dependent kinase inhibitor 1 Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P01106 P05549 P38936 Q92754 Q9UGL1	AP2TF BHLHE39 CAP20 CDKN1 CDKN1A CIP1 JARID1B KDM5B MDA6 MYC PIC1 PLU1 RBBP2H1 SDI1 TFAP2 TFAP2A TFAP2C WAF1	Homo sapiens (human)
Cysteine formation from homocysteine	Cystathionine beta-synthase Cystathionine gamma-lyase	P32929 P35520	CBS CTH	Homo sapiens (human)
LTC4-CYSLTR mediated IL4 production	Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Dipeptidase 1 Dipeptidase 2 Dipeptidase 3 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme	P16444 P19440 P36269 Q9H4A9 Q9H4B8 Q9NS75 Q9Y271	CYSLT1 CYSLT2 CYSLT2R CYSLTR1 CYSLTR2 DPEP1 DPEP2 DPEP3 GGT GGT1 GGT5 GGTLA1 MDP RDP	Homo sapiens (human)
Leukotriene receptors	Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Uracil nucleotide/cysteinyl leukotriene receptor	Q13304 Q15722 Q9NPC1 Q9NS75 Q9Y271	BLT BLT1 BLT2R BLTR BLTR2 CMKRL1 CYSLT1 CYSLT2 CYSLT2R CYSLTR1 CYSLTR2 GPR16 GPR17 LTB4R LTB4R2 P2RY7	Homo sapiens (human)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing protein Rho-related GTP-binding protein RhoQ	P13569 P17081 Q9HD26	ABCC7 ARHQ CAL CFTR FIG GOPC RASL7A RHOQ TC10	Homo sapiens (human)
Transport of inorganic cations/anions and amino acids/oligopeptides	Cystinosin Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Excitatory amino acid transporter 5 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	O00341 O60931 P43003 P43004 P43005 P48664 Q70HW3 Q9H598	CTNS EAAC1 EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 GLAST GLAST1 GLT1 HEAAC1 SAMC SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1 VGAT VIAAT	Homo sapiens (human)
Pyrimidine salvage	Cytidine deaminase Deoxycytidine kinase Pseudouridine-5'-phosphatase Thymidine kinase 2, mitochondrial Thymidine kinase, cytosolic Thymidine phosphorylase Uridine phosphorylase 1 Uridine phosphorylase 2 Uridine-cytidine kinase 1 Uridine-cytidine kinase 2 Uridine-cytidine kinase-like 1	O00142 O95045 P04183 P19971 P27707 P32320 Q08623 Q16831 Q9BZX2 Q9HA47 Q9NWZ5	CDA CDD DCK DXF68S1E ECGF1 FAM16AX GS1 HDHD1 HDHD1A PUDP TK1 TK2 TYMP UCK1 UCK2 UCKL1 UMPK UP UPP1 UPP2 URK1 URKL1	Homo sapiens (human)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Cytochrome P450 1A1 Cytochrome P450 1A2 Cytochrome P450 1B1 Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2U1 Cytochrome P450 4A11 Cytochrome P450 4F2	P04798 P05177 P10632 P11712 P33261 P78329 Q02928 Q16678 Q7Z449	CYP1A1 CYP1A2 CYP1B1 CYP2C10 CYP2C19 CYP2C8 CYP2C9 CYP2U1 CYP4A11 CYP4A2 CYP4F2	Homo sapiens (human)
Biosynthesis of protectins	Cytochrome P450 1A1 Cytochrome P450 1A2 Leukotriene A-4 hydrolase Polyunsaturated fatty acid lipoxygenase ALOX15	P04798 P05177 P09960 P16050	ALOX15 CYP1A1 CYP1A2 LOG15 LTA4 LTA4H	Homo sapiens (human)

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