GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Fatty acyl-CoA biosynthesis	(3R)-3-hydroxyacyl-CoA dehydrogenase 3-oxoacyl-[acyl-carrier-protein] reductase ATP-citrate synthase Acetyl-CoA carboxylase 1 Fatty acid synthase Long-chain fatty acid transport protein 2 Lysosomal thioesterase PPT2 MORC family CW-type zinc finger 2 Palmitoyl-protein thioesterase 1 Ribonuclease P/MRP subunit p14 Stearoyl-CoA desaturase 2	A0A8I6A0M8 D4A2C4 O70489 P11497 P12785 P16638 P45479 P97524 Q6MGB5 Q6P7B9 Q7TS56	Acac Acaca Acly Acsvl1 Cbr4 Cln1 Facvl1 Fasn Fatp2 Hsd17b8 Morc2 Ppt Ppt1 Ppt2 Rpp14 Scd2 Slc27a2 Vlacs Vlcs	Rattus norvegicus (Norway rat)
BBSome-mediated cargo-targeting to cilium	ADP-ribosylation factor-like protein 6 Bardet-Biedl syndrome 1 Bardet-Biedl syndrome 2 protein homolog Bardet-Biedl syndrome 4 Bardet-Biedl syndrome 7 protein homolog Bardet-Biedl syndrome 9 Leucine zipper transcription factor-like protein 1 Melanin-concentrating hormone receptor 1 Protein smoothened Rab-3A-interacting protein Somatostatin receptor type 3 Tetratricopeptide repeat domain 8	A0A1P8YVD0 A0A8I6AHB5 A0A8I6GF94 D4A4U2 F1M285 P30936 P97639 P97698 Q562C6 Q62739 Q66H90 Q99MH9	Arl6 Bbs1 Bbs2 Bbs4 Bbs7 Bbs9 Gpr24 Lztfl1 Mchr1 Rab3ip Rabin3 Rabin8 Slc1 Smo Smoh Sstr3 Ttc8	Rattus norvegicus (Norway rat)
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Cystinosin, lysosomal cystine transporter Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A8I6AAR8 D3ZG79 D3ZT83 O35458 O35921 P24942 P31596 P51907	Ctns Eaac1 Eaat1 Eaat2 Eaat3 Eaat4 Glt1 Slc1a1 Slc1a2 Slc1a3 Slc1a6 Slc1a7 Slc25a26 Slc32a1 Vgat Viaat	Rattus norvegicus (Norway rat)
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 G protein subunit alpha transducin 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit gamma Phosphodiesterase Phosphodiesterase Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin	A0A8I5ZN27 D3Z8C9 D3ZDI8 D3ZSS5 D4AAI1 M0R4R9 P51489 P54311 Q62927	CNCG2 CNCG3L CNCG4 Cncg Cncg1 Cnga1 Cngb1 Gnat1 Gnb1 Gngt1 Pde6a Pde6b Pde6g RCNC2 Rho	Rattus norvegicus (Norway rat)
Neurofascin interactions	Ankyrin 1 Neurofascin Syntenin-1	A0A8I5ZJ94 P97685 Q9JI92	Ank1 Nfasc Sdcbp	Rattus norvegicus (Norway rat)
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein T Centromere protein U Centromere protein W Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 MIS18 binding protein 1 Nucleophosmin Opa interacting protein 5 Protein Mis18-alpha RB binding protein 4, chromatin remodeling factor Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	A0A0G2JXI9 A0A0G2K615 A0A1W2Q6F6 A0A8I5ZQQ5 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A3Y0 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AQI0 A0A8I6AWT3 A0A8I6G659 A1L1L1 A9UMV8 B2RZC4 D3Z896 D3ZGQ8 D3ZKM9 D3ZVK7 D3ZXP3 D4A1W1 D4A9X9 D4AC25 D4ACM0 E9PSW8 F1M389 G3V9C7 M0RBQ5 P0CC09 P13084 P60123 P62804 Q00729 Q3ZAU7 Q4V8G7 Q561R1 Q5U1Z7 Q5U2W4 Q63517 Q66H02 Q71UF4	Cenpc Cenpc1 Cenph Cenpi Cenpk Cenpl Cenpm Cenpn Cenpo Cenpp Cenpq Cenpr Cenpt Cenpu Cenpw Cug2 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Fshprh1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist4 Hist4h4 Hjurp Itgb3bp Knl1 LOC100365043 LOC100910200 LOC120097726 LOC679342 LOC681185 LOC684797 Lrpr1 Mis18a Mis18bp1 Mlf1ip Npm1 Nrif3 Oip5 Rbbp4 Rbbp7 Rsf1 Ruvbl1 Smarca5 Th2b Tip49 Tip49a	Rattus norvegicus (Norway rat)
Processing of SMDT1	AFG3 like matrix AAA peptidase subunit 2 ATP-dependent zinc metalloprotease YME1L1 Calcium uniporter protein Calcium uniporter regulatory subunit MCUb Calcium uptake protein 1, mitochondrial Calcium uptake protein 2, mitochondrial Essential MCU regulator, mitochondrial Mitochondrial calcium uptake family, member 3 Mitochondrial inner membrane m-AAA protease component paraplegin Mitochondrial-processing peptidase subunit alpha Mitochondrial-processing peptidase subunit beta Presenilin-associated rhomboid-like protein, mitochondrial Prohibitin 1 Prohibitin-2 Stomatin-like protein 2, mitochondrial m-AAA protease-interacting protein 1, mitochondrial	A0A0G2K059 A0A8I6A2H6 A0A8I6ASM9 F1LN92 F1LUQ0 P20069 P67779 Q03346 Q3B8P0 Q4FZT0 Q5XIH7 Q6AY04 Q6P6Q9 Q7TT47 Q925S8 Q99P63	Afg3l2 Bcap37 Cbara1 Efha1 Maip1 Mcu Mcub Micu1 Micu2 Micu3 Mppa Mppb Parl Phb Phb1 Phb2 Pmpca Pmpcb Psarl Smdt1 Smhs2 Spg7 Stoml2 Yme1l1	Rattus norvegicus (Norway rat)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase Alpha-1,3-glucosyltransferase Alpha-1,3/1,6-mannosyltransferase ALG2 Dol-P-Man Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase Mannose-P-dolichol utilization defect 1 Mannosyltransferase Mannosyltransferase UDP-N-acetylglucosamine transferase subunit ALG13 UDP-N-acetylglucosamine transferase subunit ALG14 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	A0A8I6B3Y3 B1WBY3 D3ZCW5 D4A5S6 E9PT91 F7EMK2 G3V6U3 M0R7D2 Q3T1L5 Q5I0K7 Q6AY85	Alg1 Alg12 Alg13 Alg14 Alg2 Alg3 Alg6 Alg8 Alg9 Dpagt1 Mpdu1	Rattus norvegicus (Norway rat)
DAP12 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Beta-2-microglobulin GRB2-related adaptor protein 2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Killer cell lectin like receptor C1 Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 NKG2-D type II integral membrane protein Natural killer cells antigen CD94 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Proto-oncogene tyrosine-protein kinase LCK Ras-related C3 botulinum toxin substrate 1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3	A0A0G2JUX8 A0A0G2K344 A0A0G2K6M9 A0A8I5ZPB5 A0A8J8YIH6 D3ZYG0 D3ZZ89 D4A3T0 O35778 O70215 O70601 P07151 P08644 P10686 P20171 P24135 P62994 Q01621 Q04970 Q3KR57 Q5M824 Q62844 Q63787 Q63788 Q64725 Q6RUV5 Q6X9T7 Q9Z1L0	Ash B2m Btk Cd94 Dap12 Fyn Grap2 Grb2 Hras Hras1 Klrc1 Klrd1 Klrk1 Kras Kras2 Lat Lck Lcp2 Nkg2d Nkrp2 Nras Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg1 Plcg2 Rac Rac1 Shc1 Sos1 Syk Trem2 Tyrobp Vav2 Vav3	Rattus norvegicus (Norway rat)
Interconversion of nucleotide di- and triphosphates	Adenylate kinase 2, mitochondrial Adenylate kinase 4, mitochondrial Adenylate kinase 5 Adenylate kinase 7 Adenylate kinase 8 Adenylate kinase 8 Adenylate kinase isoenzyme 1 Adenylate kinase isoenzyme 6 CTP synthase 2 CTP synthase Deoxycytidylate deaminase Deoxyuridine 5'-triphosphate nucleotidohydrolase Glutaredoxin-1 Glutathione reductase (Fragment) NAD(+) diphosphatase Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleoside diphosphate kinase Ribonucleoside-diphosphate reductase subunit M2 Ribonucleoside-diphosphate reductase Ribonucleotide reductase regulatory TP53 inducible subunit M2B Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidylate synthase UMP-CMP kinase dTMP kinase guanylate kinase	A0A0G2K524 A0A8I5Y915 A0A8I6A2B3 A0A8I6AFQ3 D4ADQ1 F1M632 F7F0L0 G3V816 M0R515 M0R7U1 O89049 P11232 P19804 P29410 P39069 P45352 P70583 P70619 Q05982 Q4KLN6 Q4KM73 Q5EB68 Q5M9G0 Q5U2N0 Q68FP8 Q9ESH6 Q9WUS0	Ak1 Ak2 Ak3l1 Ak4 Ak5 Ak6 Ak7 Ak8 Ak9 Akd2 Cinap Cmpk Cmpk1 Ctps1 Ctps2 Dctd Dtymk Dut Dutp Glrx Glrx1 Grx Gsr Guk1 Nme1 Nme2 Nme3 Nudt13 RGD1559879 Rrm1 Rrm2 Rrm2b Trxr1 Txn Txn1 Txnrd1 Tyms	Rattus norvegicus (Norway rat)
PDH complex synthesizes acetyl-CoA from PYR	Ac1164 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	D4A5G8 P08461 P26284 P49432 Q06437 Q6P6R2 Q7TQ85	Dlat Dld LOC311254 Pdha1 Pdha1l1 Pdha2 Pdhb Pdhx	Rattus norvegicus (Norway rat)
GABA receptor activation	Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit alpha-2 Gamma-aminobutyric acid receptor subunit alpha-3 Gamma-aminobutyric acid receptor subunit alpha-4 Gamma-aminobutyric acid receptor subunit alpha-5 Gamma-aminobutyric acid receptor subunit alpha-6 Gamma-aminobutyric acid receptor subunit beta-1 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-3 Gamma-aminobutyric acid receptor subunit rho-1 Gamma-aminobutyric acid receptor subunit rho-2 Gamma-aminobutyric acid receptor subunit rho-3 Gamma-aminobutyric acid type A receptor subunit theta Rho guanine nucleotide exchange factor 9	G3V875 P15431 P18508 P19969 P20236 P23576 P28471 P28473 P30191 P47742 P50572 P50573 P62813 P63079 P63138 Q9QX73	Arhgef9 Gabra-1 Gabra-2 Gabra-3 Gabra-5 Gabra-6 Gabra1 Gabra2 Gabra3 Gabra4 Gabra5 Gabra6 Gabrb-1 Gabrb-2 Gabrb-3 Gabrb1 Gabrb2 Gabrb3 Gabrg2 Gabrg3 Gabrq Gabrr1 Gabrr2 Gabrr3	Rattus norvegicus (Norway rat)
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	O88446 Q63089 Q9R0W2	Oct1 Oct2 Oct3 Slc22a1 Slc22a2 Slc22a3	Rattus norvegicus (Norway rat)
Hedgehog 'off' state	Adenylate cyclase type 10 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Cytoplasmic dynein 2 heavy chain 1 G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Intraflagellar transport 140 Intraflagellar transport 52 Intraflagellar transport 88 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 57 homolog Kinesin family member 7 Kinesin-like protein Ofd1 centriole and centriolar satellite protein Patched Protein fuzzy homolog Protein inturned Protein smoothened Rpgrip1-like Suppressor of fused homolog Tectonic-like complex member MKS1 Tetratricopeptide repeat domain 21B Tubby-like protein WD repeat domain 19 WD repeat-containing protein 35 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A0G2JZL6 A0A8I5Y075 A0A8I5ZPQ6 A0A8I6A606 A0A8I6AA62 A0A8I6GBB8 A6N6J5 D3Z8G3 D4A1V1 D4A3N4 D4A9P0 D4ACE5 F1LQT1 F1LQZ3 F1LV01 F1LY69 F1M2B7 F1M5Q2 F1M656 F1M9H1 G3V6X8 M0R5U4 P09456 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 P97698 Q03343 Q04400 Q3B756 Q499Q5 Q6UY90 Q9JJ79 Q9JKU3 Q9Z286	Adcy1 Adcy10 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Dhc1b Dlp4 Dnch2 Dnchc2 Dync2h1 Fuz Gli1 Gli2 Gli3 Gpr161 Ift122 Ift140 Ift172 Ift52 Ift57 Ift88 Intu Kif3a Kif7 LOC100364088 Mks1 Ofd1 Pdzd6 Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b Ptch Ptch1 Rpgrip1l Sac Slb Smo Smoh Sufu Ttc21b Tulp3 Wdr19 Wdr35	Rattus norvegicus (Norway rat)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Growth factor receptor-bound protein 2 Neurotrophin-4 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A244 D4A3T0 P23363 P34131 P62994 Q63604	Ash Bdnf Frs2 Grb2 Nt4 Ntf4 Ntf5 Ntrk2 Sos1 Trkb	Rattus norvegicus (Norway rat)
Interleukin-10 signaling	Interleukin 10 receptor subunit alpha Interleukin 10 receptor subunit beta Interleukin-10 Signal transducer and activator of transcription 3 Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I6AM23 D3ZD03 D3ZM36 G3V830 P29456 P52631	Il-10 Il10 Il10ra Il10rb Jak1 Stat3 Tyk2	Rattus norvegicus (Norway rat)
Signaling by ERBB2	Betacellulin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Yes	A0A8I5Y1H8 A0A8I6AQ55 F1LM93 G3V6K6 O35569 P06494 P07522 P43322 P82995 Q06175 Q62799 Q62844 Q63692 Q9WUD9 Q9Z0L5	Btc Cdc37 Dtr Egf Egfr Erbb2 Erbb3 Ereg Fyn Hbegf Hegfl Hsp86 Hsp90aa1 Hspca Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Src Yes1	Rattus norvegicus (Norway rat)
Prostanoid ligand receptors	Prostacyclin receptor Prostaglandin D2 receptor 2 Prostaglandin D2 receptor-like Prostaglandin D2 receptor Prostaglandin E2 receptor EP1 subtype Prostaglandin E2 receptor EP2 subtype Prostaglandin E2 receptor EP3 subtype Prostaglandin E2 receptor EP4 subtype Prostaglandin F2-alpha receptor Thromboxane A2 receptor	O35932 P34978 P34980 P43114 P43118 P43253 P70597 Q62928 Q6XKD3 Q9R261	Crth2 Gpr44 Ptgdr Ptgdr2 Ptgdrl Ptger1 Ptger2 Ptger3 Ptger4 Ptgfr Ptgir Tbxa2r	Rattus norvegicus (Norway rat)
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Amyloid-beta precursor protein Angiotensinogen Annexin A1 Appetite-regulating hormone B1 bradykinin receptor B2 bradykinin receptor Beta-adrenergic receptor kinase 1 Bombesin receptor subtype-3 C-C motif chemokine 6 C-C motif chemokine ligand 9 Chemokine XC receptor 1 Cholecystokinin receptor type A Cholecystokinin Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Extracellular calcium-sensing receptor Formyl peptide receptor 2 Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3 Free fatty acid receptor 4 G protein-coupled receptor 132 G protein-coupled receptor 143 G protein-coupled receptor 39 G protein-coupled receptor 68 G-protein coupled receptor 4 G-protein coupled receptor 65 G-protein coupled receptor family C group 6 member A Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Gastrin Glucagon receptor Gonadotropin-releasing hormone receptor Growth hormone secretagogue receptor type 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine H1 receptor Hypocretin neuropeptide precursor Kalirin KiSS-1 receptor Kininogen-1 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Lymphotactin Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 4 Lysophosphatidic acid receptor 5 Lysophosphatidic acid receptor 6 Melanin-concentrating hormone receptor 1 Melanopsin Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Metastasis-suppressor KiSS-1 Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M3 Muscarinic acetylcholine receptor M5 Neuromedin B Neuromedin-B receptor Neuromedin-K receptor Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Neuropeptide S receptor Neuropeptide S Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Orexigenic neuropeptide QRFP Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Oxytocin receptor Oxytocin-neurophysin 1 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 6 P2Y receptor family member 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-activating factor receptor Pro-FMRFamide-related neuropeptide FF Pro-MCH Pro-glucagon Pro-thyrotropin-releasing hormone Progonadoliberin-1 Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Prostaglandin E2 receptor EP1 subtype Prostaglandin F2-alpha receptor Protachykinin-1 Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Pyroglutamylated RFamide peptide receptor like Regulator of G-protein signaling 13 Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 18 Regulator of G-protein signaling 19 Regulator of G-protein signaling 1 Regulator of G-protein signaling 21 Regulator of G-protein signaling 2 Regulator of G-protein signaling 3 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Regulator of G-protein signaling like 1 Rho guanine nucleotide exchange factor 25 Substance-K receptor Substance-P receptor Tachykinin-3 Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Triple functional domain protein Type-1 angiotensin II receptor A Tyrosine-protein kinase Uracil nucleotide/cysteinyl leukotriene receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B Vasopressin V1a receptor Vasopressin-neurophysin 2-copeptin	A0A0G2JZN6 A0A0G2K344 A0A0G2K505 A0A0G2K6M9 A0A8I5ZV65 A0A8I5ZW42 A0A8I6A964 A0A8I6AD76 A0A8I6AF64 A0A8I6AM80 A0A8I6AWY9 A0A8I6GAY3 A0A8I6GLD4 A0A8J8XRQ3 A0A8J8Y1V6 B0YIR8 B2GV46 D3ZCS1 D3ZGG9 D3ZHA3 D3ZSW1 D4A082 D4A1W6 D4AAI1 D4ADR1 F1M0Z1 F2Z3T8 G3V8K2 O08725 O35353 O55232 O70521 O88302 O89040 P01015 P01150 P01179 P01186 P01355 P04563 P06767 P06883 P07150 P07490 P08435 P08482 P08483 P08592 P08909 P08911 P08934 P0C0L6 P0C0P7 P10687 P12760 P13207 P14200 P14600 P14842 P15823 P16177 P16610 P18292 P20068 P20789 P21451 P22388 P23385 P23943 P23944 P24053 P24393 P25023 P25095 P26684 P26817 P26824 P30082 P30551 P30553 P30560 P30969 P30994 P31390 P31424 P34978 P41232 P43118 P43140 P43425 P46002 P48442 P49651 P49684 P49797 P49799 P49800 P51672 P52287 P52500 P54311 P54313 P56700 P56718 P56719 P61794 P61954 P62882 P63077 P63219 P70536 P70597 P82471 P83860 P97583 P97639 P97844 P97924 Q01717 Q09QM4 Q2AC31 Q4G072 Q4KLH9 Q4L0E8 Q5FVN3 Q5H8A2 Q63371 Q63384 Q63645 Q63787 Q63788 Q63789 Q68FP3 Q6P720 Q70VB1 Q765I2 Q76EI6 Q7TSB7 Q8K3T4 Q8K418 Q8K5E0 Q8R413 Q8R414 Q8R415 Q8R416 Q8R456 Q920E0 Q920E1 Q924T8 Q924T9 Q924U0 Q924U1 Q99JE6 Q9EP86 Q9EQD2 Q9ESQ4 Q9JHX0 Q9JID2 Q9JJI5 Q9QW07 Q9QYH7 Q9QZQ4 Q9R0Q2 Q9WVA9	5ht1c A4 AD1 Adra1a Adra1b Adra1c Adra1d Adrbk1 Agt Agtr1 Agtr1a Anx1 Anxa1 App Arhgef25 At1a Avp Avpr1a B1bkr Bdkrb1 Bdkrb2 Bkr Blt Brs3 Btk Bv8 Casr Cck Cckar Cckbr Ccl6 Ccl9 Chrm-1 Chrm-3 Chrm-5 Chrm1 Chrm3 Chrm5 Cyslt1 Cyslt2 Cysltr1 Cysltr2 Duo Edg2 Edg7 Edn1 Edn2 Edn3 Ednra Ednrb F2 F2r F2rl1 F2rl2 F2rl3 Ffar1 Ffar2 Ffar3 Ffar4 Fpr2 Gaip Gas Gast Gcg Gcgr Geft Ghrl Ghsr Gna11 Gna14 Gna15 Gnaq Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Gnrh Gnrh1 Gnrhr Gpcr91 Gpr120 Gpr132 Gpr14 Gpr143 Gpr147 Gpr154 Gpr17 Gpr24 Gpr39 Gpr4 Gpr40 Gpr41 Gpr43 Gpr54 Gpr65 Gpr66 Gpr68 Gpr73 Gpr73l1 Gpr74 Gprc1a Gprc1e Gprc2a Gprc6a Grk2 Grm1 Grm5 Grp Grpr Hapip Hcrt Hcrtr1 Hcrtr2 Hrh1 Htr1c Htr2 Htr2a Htr2b Htr2c Kalrn Kiss1 Kiss1r Kng Kng1 Lpa1 Lpa3 Lpar1 Lpar2 Lpar3 Lpar4 Lpar5 Lpar6 Ltb4r Ltb4r2 Ltn Mch Mchr1 Mglur1 Mglur5 Nka Nkna Nknb Nmb Nmbr Nms Nmu Nmur1 Nmur2 Npff Npff1 Npff2 Npffr1 Npffr2 Npgpr Nps Npsr1 Ntr2 Nts Ntsr Ntsr1 Ntsr2 O3far1 Opn4 Ot Otr Ox Oxt Oxtr P2ru1 P2ry1 P2ry10 P2ry2 P2ry5 P2ry6 P2y5 P518 Par1 Par2 Par3 Par4 Pcar1 Pik3ca Pik3r1 Pik3r2 Pik3r3 Pkr1 Pkr2 Plcb1 Plcb2 Plcb3 Plcb4 Pmch Ppox Prok1 Prok2 Prokr1 Prokr2 Ptafr Ptger1 Ptgfr Qrfp Qrfprl RGD1560028 Rgs1 Rgs13 Rgs16 Rgs17 Rgs18 Rgs19 Rgs2 Rgs21 Rgs3 Rgs4 Rgs5 Rgsl1 Rgsr Scyc1 Senr Serpina8 Slc1 Srl Tac1 Tac1r Tac2 Tac2r Tac3 Tac3r Tacr1 Tacr2 Tacr3 Tbxa2r Tgr1 Trh Trhr Trio Urp Uts2 Uts2b Uts2d Uts2r XCR1 Xcl1 Xcr1	Rattus norvegicus (Norway rat)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor 1 Klotho	Q04589 Q8VI82 Q9Z2Y9	Fgf23 Fgfr1 Flg Kl	Rattus norvegicus (Norway rat)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormone alpha-2 Glycoprotein hormone subunit beta 5 Glycoprotein hormones alpha chain Gonadotropin-releasing hormone receptor Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Progonadoliberin-1 Thyrotropin receptor Thyrotropin subunit beta	P01230 P04652 P07490 P11962 P16235 P18427 P20395 P21463 P30969 Q5VJF5 Q925Q4	Cga Cga1 Fshb Fshr Gnrh Gnrh1 Gnrhr Gpa2 Gpb5 Gpha2 Gphb5 Lhb Lhcgr Tshb Tshr Zsig51	Rattus norvegicus (Norway rat)
Synthesis of PI	CDP-diacylglycerol--inositol 3-phosphatidyltransferase Membrane-associated phosphatidylinositol transfer protein 1 PITPNM family member 3 Phosphatidate cytidylyltransferase 1 Phosphatidylinositol transfer protein, membrane-associated 2	A0A8I6AUE0 M0RDK4 O35052 P70500 Q5U2N3	Cdipt Cds Cds1 Nir2 Pis1 Pitpnm Pitpnm1 Pitpnm2 Pitpnm3	Rattus norvegicus (Norway rat)
GPVI-mediated activation cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3-phosphoinositide-dependent protein kinase 1 C-type lectin domain family 1 member B Cell division control protein 42 homolog Glycoprotein VI High affinity immunoglobulin epsilon receptor subunit gamma Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase, regulatory subunit 6 Podoplanin Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene vav Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5ZPB5 A0A8I6A1P8 A0A8I6G942 A0A8J8YIH6 D3ZFJ0 D3ZJD8 D3ZYG0 D4A4I3 M0R8A3 O55173 O70601 P20411 P24135 P41499 P54100 P61589 P62747 P81718 Q01621 Q07014 Q32PX6 Q62844 Q63787 Q63788 Q63789 Q64294 Q64725 Q6MG59 Q6RUV5 Q8CFN2 Q9Z1L0	Arha Arha2 Arhb Cdc42 Clec1b Fce1g Fcer1g Fyn G6b Gp6 Lat Lck Lcp2 Lyn Mpig6b Pdk1 Pdpk1 Pdpn Pik3ca Pik3cb Pik3cg Pik3r1 Pik3r2 Pik3r3 Pik3r5 Pik3r6 Plcg2 Ptph6 Ptpn11 Ptpn6 Rac Rac1 Rac2 Rhoa Rhob Rhog Syk Vav Vav1 Vav2 Vav3	Rattus norvegicus (Norway rat)
Glycosphingolipid biosynthesis	2-hydroxyacylsphingosine 1-beta-galactosyltransferase Alpha-2,8-sialyltransferase 8E Beta-1,3-galactosyltransferase 4 Beta-1,4 N-acetylgalactosaminyltransferase 1 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 Ceramide glucosyltransferase Ceramide kinase Galactose-3-O-sulfotransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 UDP-GalNAc	A0A0G2K3K5 D3Z9Y3 D3ZCT9 M0R3S4 O88178 O88419 Q02734 Q09426 Q10468 Q10980 Q10984 Q11205 Q68G12 Q6AY39 Q6ZXC8 Q6ZXY9 Q99NB2 Q9JI93 Q9R0E0	A4galt B3galnt1 B3galt3 B3galt4 B3gnt5 B4galnt1 B4galt5 B4galt6 Cerk Cgt Fta Ftb Fut1 Fut2 Gal3st1 Galgt Galgt1 Sec1 Siat4b Siat5 Siat6 Siat8e Siat9 St3gal2 St3gal3 St3gal5 St6galnac5 St6galnac6 St8sia5 St8siav Ugcg Ugt4 Ugt8	Rattus norvegicus (Norway rat)
G alpha (s) signalling events	3',5'-cyclic-AMP phosphodiesterase 4A 3',5'-cyclic-AMP phosphodiesterase 4C (Fragment) 3',5'-cyclic-AMP phosphodiesterase 4D Beta-2 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 5 G protein-coupled receptor kinase 6 High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (Fragment) Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B	A0A8I5ZTX5 A0A8I5ZWQ4 A0A8I6A416 O08593 P10608 P14270 P14644 P26817 P26819 P29066 P29067 P54748 P97711 Q01062 Q01066 Q62833 Q62865 Q63085 Q76KC6 Q8VID6 Q9QYJ6	Adrb2 Adrb2r Adrbk1 Adrbk2 Arrb1 Arrb2 Dpde1 Gprk5 Gprk6 Grk2 Grk3 Grk5 Grk6 Pde10a Pde11a Pde1a Pde1b Pde1b1 Pde2a Pde3a Pde3b Pde4a Pde4c Pde4d Pde7a Pde7b Pde8a Pde8b RNPDE8A	Rattus norvegicus (Norway rat)

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