GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZUM2 D3ZXR7 M0RA08 Q56DL5 Q63691 Q9QX05	Cd14 Ly96 Plin3 Sarm1 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase-activating protein Cytochrome P450 4A10 Cytochrome P450 4A12 Cytochrome P450 4A14 Cytochrome P450 4A2 Cytochrome P450 4B1 Cytochrome P450 4F1 Cytochrome P450 4F3 Cytochrome P450 4F4 Cytochrome P450, family 4, subfamily f, polypeptide 40 Dipeptidase 1 Dipeptidase 2 Dipeptidase 3 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Leukotriene A-4 hydrolase Leukotriene C4 synthase MAPK activated protein kinase 2 Multidrug resistance-associated protein 1 Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15	D3ZTC9 P07314 P08516 P12527 P15129 P20291 P20816 P20817 P24464 P30349 P31430 P33274 P51869 Q02759 Q3MID2 Q5M872 Q5U2X4 Q80ZF4 Q8CG09 Q925U2 Q9QWE9	Abcc1 Alox12l Alox15 Alox5 Alox5ap Cyp4a-1 Cyp4a-2 Cyp4a-3 Cyp4a-8 Cyp4a1 Cyp4a10 Cyp4a11 Cyp4a12 Cyp4a14 Cyp4a2 Cyp4a3 Cyp4a8 Cyp4b-1 Cyp4b1 Cyp4f-1 Cyp4f1 Cyp4f18 Cyp4f2 Cyp4f3 Cyp4f4 Cyp4f40 Dpep1 Dpep2 Dpep3 Flap Ggt Ggt1 Ggt5 Ggtla1 Lta4h Ltc4s Mapkapk2 Mrp1 Rdp	Rattus norvegicus (Norway rat)
Voltage gated Potassium channels	Potassium voltage-gated channel modifier subfamily F member 1 Potassium voltage-gated channel modifier subfamily G member 4 Potassium voltage-gated channel modifier subfamily V member 2 Potassium voltage-gated channel subfamily A member 10 Potassium voltage-gated channel subfamily A member 1 Potassium voltage-gated channel subfamily A member 2 Potassium voltage-gated channel subfamily A member 3 Potassium voltage-gated channel subfamily A member 4 Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily A member 6 Potassium voltage-gated channel subfamily A member 7 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily B member 2 Potassium voltage-gated channel subfamily C member 1 Potassium voltage-gated channel subfamily C member 2 Potassium voltage-gated channel subfamily C member 3 Potassium voltage-gated channel subfamily C member 4 Potassium voltage-gated channel subfamily D member 1 Potassium voltage-gated channel subfamily D member 2 Potassium voltage-gated channel subfamily D member 3 Potassium voltage-gated channel subfamily G member 1 Potassium voltage-gated channel subfamily G member 2 Potassium voltage-gated channel subfamily G member 3 Potassium voltage-gated channel subfamily H member 1 Potassium voltage-gated channel subfamily H member 2 Potassium voltage-gated channel subfamily H member 3 Potassium voltage-gated channel subfamily H member 4 Potassium voltage-gated channel subfamily H member 5 Potassium voltage-gated channel subfamily H member 6 Potassium voltage-gated channel subfamily H member 7 Potassium voltage-gated channel subfamily H member 8 Potassium voltage-gated channel subfamily KQT member 1 Potassium voltage-gated channel subfamily Q member 5 Potassium voltage-gated channel subfamily S member 1 Potassium voltage-gated channel subfamily S member 2 Potassium voltage-gated channel subfamily S member 3 Potassium voltage-gated channel subfamily V member 1 Voltage-gated potassium channel subunit beta-1 Voltage-gated potassium channel subunit beta-2 Voltage-gated potassium channel subunit beta-3	D3ZRW4 D3ZYK3 D3ZZR6 D4A810 D4AD53 D4AD66 D4ADX7 F1LY25 O08962 O54852 O54853 O88758 O88759 O89047 P10499 P15384 P15385 P15387 P17659 P19024 P22462 P25122 P62483 P63142 P63144 P97557 Q01956 Q62897 Q63099 Q63472 Q63494 Q63734 Q63881 Q8R523 Q9EPI9 Q9ER26 Q9QWS8 Q9QYU3 Q9R1T9 Q9Z0N7	Ckbeta2 Ckbeta3 Eag Eag2 Elk1 Elk2 Elk3 Erg Erg2 Erg3 Kcna1 Kcna10 Kcna2 Kcna3 Kcna4 Kcna5 Kcna6 Kcna7 Kcna9 Kcnab1 Kcnab2 Kcnab3 Kcnb1 Kcnb2 Kcnb3 Kcnc1 Kcnc2 Kcnc3 Kcnc4 Kcnd1 Kcnd2 Kcnd3 Kcnf1 Kcng1 Kcng2 Kcng3 Kcng4 Kcnh1 Kcnh2 Kcnh3 Kcnh4 Kcnh5 Kcnh6 Kcnh7 Kcnh8 Kcnq1 Kcnq5 Kcns1 Kcns2 Kcns3 Kcnv1 Kcnv2 Kvb1 Kvlqt1	Rattus norvegicus (Norway rat)
Platelet Aggregation (Plug Formation)	Glycoprotein 9 Glycoprotein Ib platelet subunit alpha Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin	D3ZQU7 O08770 P18292 Q4AEG0 Q9JJM7	F2 Gp1ba Gp1bb Gp5 Gp9	Rattus norvegicus (Norway rat)
DSCAM interactions	Cell adhesion molecule DSCAM DS cell adhesion molecule-like 1	D3ZPL7 Q8VHZ8	Dscam Dscaml1	Rattus norvegicus (Norway rat)
Butyrophilin (BTN) family interactions	Butyrophilin, subfamily 1, member A1 Butyrophilin, subfamily 2, member A2 Butyrophilin-like 9 Butyrophilin-like protein 2 CD209a molecule Periplakin Xanthine dehydrogenase/oxidase	D3ZP17 D4A076 D4A5T8 F1LRV5 M0R7E0 P22985 Q6MG97	Btn1a1 Btn2a2 Btnl2 Btnl9 Cd209a LOC684480 Ppl Xdh	Rattus norvegicus (Norway rat)
Ribavirin ADME	Adenosine deaminase Adenosine kinase Cytosolic purine 5'-nucleotidase Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 3 Inosine triphosphate pyrophosphatase Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Purine nucleoside phosphorylase Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	D3ZMY7 D3ZW55 O54698 P19804 P85973 Q05982 Q62773 Q64640 Q80WK7 Q8VIH3 Q920P6	Ada Adk Cnt2 Cnt3 Ent1 Ent3 Itpa Nme1 Nme2 Np Nt5c2 Pnp Slc28a2 Slc28a3 Slc29a1 Slc29a3 Spnt	Rattus norvegicus (Norway rat)
Tryptophan catabolism	3-hydroxyanthranilate 3,4-dioxygenase Amino acid transporter heavy chain SLC3A2 Indoleamine 2,3-dioxygenase 1 Indoleamine 2,3-dioxygenase 2 Kynureninase Kynurenine 3-monooxygenase Kynurenine--oxoglutarate transaminase 1 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Large neutral amino acids transporter small subunit 1 Solute carrier family 36 member 4 Tryptophan 2,3-dioxygenase	D3ZMH7 F1LV46 O88867 P21643 P46953 P70712 Q08415 Q63016 Q64602 Q794F9 Q9ERD9	Aadat Ccbl1 Haao Ido Ido1 Ido2 Indo Indol1 Kat Kat2 Kmo Kyat1 Kynu Lat1 Mpe16 Slc36a4 Slc3a2 Slc7a5 Ta1 Tdo Tdo2	Rattus norvegicus (Norway rat)
Receptor Mediated Mitophagy	Autophagy protein 5 Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta FUN14 domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Proto-oncogene tyrosine-protein kinase Src Serine/threonine-protein kinase Serine/threonine-protein phosphatase PGAM5, mitochondrial Ubiquitin-like protein ATG12	D3ZMG0 F7FH41 P19139 P67874 Q2TBJ5 Q3MQ06 Q562B5 Q5BJS4 Q62625 Q6XVN8 Q9WUD9	Apg12l Atg12 Atg5 Ck2n Csnk2a1 Csnk2a2 Csnk2b Fundc1 Map1alc3 Map1lc3 Map1lc3a Map1lc3b Pgam5 Src Ulk1	Rattus norvegicus (Norway rat)
Phase 4 - resting membrane potential	ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 14 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4 Potassium channel subfamily K member 10 Potassium channel subfamily K member 12 Potassium channel subfamily K member 13 Potassium channel subfamily K member 15 Potassium channel subfamily K member 18 Potassium channel subfamily K member 1 Potassium channel subfamily K member 2 Potassium channel subfamily K member 3 Potassium channel subfamily K member 4 Potassium channel subfamily K member 9 Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel, subfamily K, member 5 Potassium two pore domain channel subfamily K member 16	D3ZLR9 D4A806 G3V8R8 G3V8V5 O54912 O70596 P52188 P52190 Q2KTA6 Q64273 Q6Q1P3 Q8R5I0 Q920B6 Q9ERS0 Q9ERS1 Q9ES08 Q9JIS4 Q9Z2T2	Irk1 Irk2 Irk3 Irk4 Kcnj12 Kcnj14 Kcnj2 Kcnj4 Kcnk1 Kcnk10 Kcnk12 Kcnk13 Kcnk15 Kcnk16 Kcnk18 Kcnk2 Kcnk3 Kcnk4 Kcnk5 Kcnk6 Kcnk7 Kcnk9 LOC364241 Task Task1 Task3 Task5 Trek Trek2 Tresk-2 Tresk2	Rattus norvegicus (Norway rat)
Synthesis of 12-eicosatetraenoic acid derivatives	Arachidonate 12-lipoxygenase, 12R-type Glutathione peroxidase 1 Glutathione peroxidase 2 Hydroperoxide isomerase ALOXE3 Phospholipid hydroperoxide glutathione peroxidase Polyunsaturated fatty acid lipoxygenase ALOX12 Polyunsaturated fatty acid lipoxygenase ALOX15	D3ZKX9 F1LQ70 P04041 P36970 P83645 Q02759 Q2KMM4	Alox12 Alox12b Alox12l Alox15 Aloxe3 Gpx1 Gpx2 Gpx4	Rattus norvegicus (Norway rat)
Switching of origins to a post-replicative state	Chromatin licensing and DNA replication factor 1 Geminin, DNA replication inhibitor	D3ZKD4 D3ZWJ0	Cdt1 Gmnn	Rattus norvegicus (Norway rat)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Procathepsin L Serpin family B member 13 Similar to Cathepsin L precursor (Major excreted protein) (MEP)	D3ZKA0 D3ZKC3 O35186 P07154	Cts7l2 Ctsk Ctsl Ctsl1 Ctsll3 RGD1308751 Serpinb13	Rattus norvegicus (Norway rat)
Heme signaling	Apolipoprotein A-I Apolipoprotein B-100 BTB domain and CNC homolog 1 C-type lectin domain family 1 member B Exportin-1 Hemoglobin subunit alpha-1/2 Hemoglobin subunit beta-1 Lymphocyte antigen 96 Membrane-associated progesterone receptor component 2 Proton-coupled folate transporter Toll-like receptor 4	D3ZJD8 D4ACD2 P01946 P02091 P04639 Q56DL5 Q5EBA8 Q5XIU9 Q7TMA5 Q80U96 Q9QX05	Apoa1 Apob Bach1 Clec1b Crm1 Hba-a1 Hba1 Hbb Hcp1 LOC100911490 Ly96 Pcft Pgrmc2 Slc46a1 Tlr4 Xpo1	Rattus norvegicus (Norway rat)
Metal ion SLC transporters	Ceruloplasmin Hephaestin High affinity copper uptake protein 1 Natural resistance-associated macrophage protein 1 Natural resistance-associated macrophage protein 2 Solute carrier family 30, member 10 Solute carrier family 40 member 1 Solute carrier family 41 member Solute carrier family 41 member	D3ZJB7 D3ZM22 D4A7D4 O54902 P13635 P70553 Q920H8 Q923U9 Q9JK41	Bcg Copt1 Cp Ctr1 Dct1 Dmt1 Fpn1 Fpt1 Heph Nramp1 Nramp2 Slc11a1 Slc11a2 Slc30a10 Slc31a1 Slc40a1 Slc41a1 Slc41a2	Rattus norvegicus (Norway rat)
Chromatin modifying enzymes	Bromodomain and WD repeat domain containing 1 Histone H3.1 Histone H3 Protein-arginine deiminase type-1 Protein-arginine deiminase type-2 Protein-arginine deiminase type-3 Protein-arginine deiminase type-4 Protein-arginine deiminase Transcription activator BRG1	D3ZJ08 D4AAI9 D4ABN7 O88806 O88807 P20717 P70708 Q6LED0 Q8K1P7	Baf190a Brg1 Brwd1 H3c13 Hist2h3c2 Pad1 Pad2 Pad3 Pad4 Padi1 Padi2 Padi3 Padi4 Padi6 Pdi Pdi1 Pdi2 Pdi3 Pdi4 Smarca4 Snf2b Snf2l4	Rattus norvegicus (Norway rat)
RHO GTPases activate PKNs	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta 3-phosphoinositide-dependent protein kinase 1 M-phase inducer phosphatase Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 14A Protein phosphatase 1 regulatory subunit Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Stratifin Transforming protein RhoA	D3ZIC4 D4ADT2 G3V9A3 O08874 O55173 P35213 P61589 P61983 P62142 P62260 P62747 P63102 P68255 P68511 Q10728 Q63433 Q6RUV5 Q99MC0	Arha Arha2 Arhb Cdc25c Cpi Cpi17 Mbs Msfs1 Mypt1 Pak2 Pdk1 Pdpk1 Pkn Pkn1 Pkn2 Ppp1cb Ppp1r12a Ppp1r12b Ppp1r14a Prk1 Prk2 Prkcl1 Prkcl2 Rac Rac1 Rhoa Rhob Sfn Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase B, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA thioesterase 4 Acyl-CoA thioesterase 6 Acyl-coenzyme A thioesterase 8 Enoyl-CoA delta isomerase 2 Malonyl-CoA decarboxylase, mitochondrial Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2	D3ZHR2 D3ZIQ1 D3ZSE3 P07871 P07872 P07896 P97852 Q5XIC0 Q8VHK0 Q920F5 Q9Z2M4	Abcd1 Acaa1 Acaa1b Acot4 Acot6 Acot8 Acox Acox1 Decr2 Eci2 Edh17b4 Ehhadh Hsd17b4 Mfe1 Mlycd Peci Pte1	Rattus norvegicus (Norway rat)
Ephrin signaling	ARF GTPase-activating protein GIT1 Cytoplasmic protein Ephrin B3 Ephrin type-B receptor 1 Ephrin type-B receptor 3 Ephrin type-B receptor 6 Ephrin-B1 Myosin regulatory light chain RLC-A Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Syntenin-1 Tyrosine-protein kinase Fyn receptor protein-tyrosine kinase receptor protein-tyrosine kinase	D3ZH39 D4A3M8 F1MAJ0 G3V7D4 M0RDA4 O55043 P09759 P0C0K7 P13832 P35465 P52796 Q62829 Q62844 Q64303 Q6RUV5 Q9JI92 Q9WUD9 Q9Z272	Arhgef7 Efnb1 Efnb3 Elk Ephb1 Ephb2 Ephb3 Ephb4 Ephb6 Eplg2 Epth2 Fyn Git1 LOC686310 Lerk2 Nck2 Pak1 Pak2 Pak3 Pak3bp Pixb Rac Rac1 Rlc-a Sdcbp Src	Rattus norvegicus (Norway rat)
Ligand-receptor interactions	Cell adhesion molecule-related/down-regulated by oncogenes Hedgehog protein Hedgehog protein Hedgehog-interacting protein Patched Sonic hedgehog protein	D3ZGL3 F1LP42 G3V7Y0 O35158 Q63673 Q6UY90	Cdo Cdon Dhh Hhip Ihh Ptch Ptch1 Shh Vhh-1	Rattus norvegicus (Norway rat)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	D3ZGB8 P01346 P08025 P24062	Cilp Igf-1 Igf-2 Igf1 Igf1r Igf2	Rattus norvegicus (Norway rat)
RA biosynthesis pathway	Alcohol dehydrogenase 1 Aldehyde dehydrogenase 1A1 Aldehyde dehydrogenase 8 family, member A1 Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Cellular retinoic acid-binding protein 1 Cytochrome P450 26A1 Cytochrome P450 26B1 Cytochrome P450, family 26, subfamily C, polypeptide 1 Dehydrogenase/reductase SDR family member 4 Dehydrogenase/reductase SDR family member 9 LRRGT00111 Retinal dehydrogenase 2 Retinaldehyde dehydrogenase 3 Retinol dehydrogenase 10 Retinol dehydrogenase 13 Retinol dehydrogenase 14 Retinol dehydrogenase 7 Short chain dehydrogenase/reductase family 16C, member 5	D3ZFR9 D3ZS85 D3ZUY0 D3ZXY4 D4AAL3 G3V7X8 G3V861 P06757 P51647 P55006 P62966 Q3MHS3 Q63639 Q64563 Q6AYQ2 Q6TUD3 Q80ZF7 Q8K4D8 Q8VD48 Q8VID1	Adh-1 Adh1 Adh2 Adh4 Akr1c1 Akr1c21 Aldh Aldh1a1 Aldh1a2 Aldh1a3 Aldh6 Aldh8a1 Crabp1 Cyp26a1 Cyp26b1 Cyp26c1 Dhrs4 Dhrs9 Hsd17b5 LOC683474 Raldh2 Raldh3 Rdh10 Rdh11 Rdh13 Rdh14 Rdh3 Rdh7 Sdr16c5 eRolDH	Rattus norvegicus (Norway rat)
Uptake of dietary cobalamins into enterocytes	Cobalamin binding intrinsic factor Cubilin Protein amnionless	D3ZFK9 O70244 P17267	Amn Cblif Cubn Gif Ifcr	Rattus norvegicus (Norway rat)
HDL clearance	Apolipoprotein A-I Cubilin Protein amnionless Scavenger receptor class B member 1 Vigilin	D3ZFK9 O70244 P04639 P97943 Q9Z1A6	Amn Apoa1 Cubn Hbp Hdlbp Ifcr Scarb1	Rattus norvegicus (Norway rat)
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase-1 Hyaluronidase-3 Iduronate 2-sulfatase Neurocan core protein Versican core protein (Fragments)	D3ZE16 F1LLW8 P47853 P50430 P55067 P55068 Q00657 Q01129 Q641X3 Q6AXR4 Q76HM9 Q76HN1 Q9ERB4 Q9ERQ6	Arsb Bcan Behab Bgn Caleb Cspg2 Cspg3 Cspg4 Cspg5 Dcn Hexa Hexb Hyal1 Hyal3 Ids Idua LOC100363795 Ncan Ng2 Ngc Vcan	Rattus norvegicus (Norway rat)	G27025MB

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