GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **426 - 450** of **1070** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Formation of xylulose-5-phosphate	Aldo-keto reductase family 1 member A1 L-xylulose reductase Lambda-crystallin homolog Sorbitol dehydrogenase Xylulose kinase	P27867 P51635 Q3MIF4 Q811X6 Q920P0	Akr1a1 Alr Cry Cryl1 Dcxr Glb Sdh1 Sord Xylb	Rattus norvegicus (Norway rat)
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	P07943 P27867	Akr1b1 Akr1b4 Aldr1 Sdh1 Sord	Rattus norvegicus (Norway rat)	G58161NS
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 Carbonyl reductase [NADPH] 1 Cytochrome P450 family 8 subfamily B member 1 Hematopoietic prostaglandin D synthase Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase	D4AE56 G3V8J2 O35543 P22057 P35355 P47727 P49430 P83868 Q3MHS3 Q62969 Q63921 Q6AYQ2 Q9JHF3	Akr1c1 Akr1c21 Cbr Cbr1 Cox-1 Cox-2 Cox1 Cox2 Cyp5 Cyp5a1 Cyp8 Cyp8b1 Gsts Hpgds Hsd17b5 Pgds Pges Pig12 Ptgds Ptgds2 Ptges Ptges2 Ptges3 Ptgis Ptgs1 Ptgs2 Tbxas1 Tebp	Rattus norvegicus (Norway rat)
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-mannosidase 2 Alpha-mannosidase Carbohydrate sulfotransferase 10 Tissue alpha-L-fucosidase	A0A0G2JWG1 O54702 P17164 P28494 Q09326 Q6EV76	Chst10 Fuca Fuca1 Fut8 Gnt2 Man2a1 Man2a2 Mana2 Mgat2	Rattus norvegicus (Norway rat)	G70323CJ G82576YO
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Glycoprotein endo-alpha-1,2-mannosidase	Q09325 Q5GF25	Gnt1 Manea Mgat1	Rattus norvegicus (Norway rat)	G58161NS
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A Alpha-2,8-sialyltransferase 8B Beta-1,4-galactosyltransferase 3 Beta-1,4-galactosyltransferase 4 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 MGAT4 family, member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	A0A0G2K3K5 B2GV39 D3ZEV3 D4A2A5 G3V8D0 O88419 P13721 P61131 Q07977 Q08834 Q5M854 Q66HH1 Q6P768	B4galt2 B4galt3 B4galt4 B4galt5 B4galt6 Mgat4a Mgat4b Mgat4c Mgat5 Siat1 Siat4c Siat8b St3gal4 St6gal1 St8sia2 St8sia3 Stx	Rattus norvegicus (Norway rat)	G81533KY
O-linked glycosylation of mucins	Alpha-1,4-N-acetylglucosaminyltransferase Beta 1,6-N-acetylglucosaminyltransferase Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase C1GALT1-specific chaperone 1 Glucosaminyl (N-acetyl) transferase 1 Glucosaminyl (N-acetyl) transferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Mucin 15, cell surface associated Mucin 19, oligomeric Mucin 20, cell surface associated Mucin 5AC, oligomeric mucus/gel-forming Mucin 5B, oligomeric mucus/gel-forming Mucin 6, oligomeric mucus/gel-forming Mucin-13 Mucin-1 Mucin-2 (Fragment) Mucin-4 N-acetylgalactosaminyltransferase 7 Polypeptide N-acetylgalactosaminyltransferase 10 Polypeptide N-acetylgalactosaminyltransferase 11 Polypeptide N-acetylgalactosaminyltransferase 13 Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 5 Polypeptide N-acetylgalactosaminyltransferase-like 5 Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Queuosine-tRNA galactosyltransferase Sulfotransferase UDP-GlcNAc	A0A0G2JXL5 A0A0G2K1Q3 A0A0G2K3K5 A0A0G2K8X5 A0A8I5ZYW6 A0A8I6AAU0 A0A8I6ARU0 A0A8I6AU26 A0A8I6GM17 A0A8J8XFR5 D3ZAU0 D3ZBX5 D3ZC66 D3ZE36 D3ZEF9 D3ZG90 D3ZLS2 D3ZQA1 D3ZX31 D4A3A9 D4A3H6 D4A6I9 D4A849 D4A864 F1LQN1 F7EK02 O88419 O88422 P97881 Q10473 Q499P3 Q5CD99 Q62635 Q63661 Q64165 Q66H69 Q6AYL7 Q6GV29 Q6P6V1 Q6UE39 Q8CH87 Q925R7 Q99NB2 Q9JJ05 Q9R0C5	A4gnt AC096792.1 B3gnt2 B3gnt3 B3gnt4 B3gnt5 B3gnt6 B3gnt7 B3gnt8 B3gnt9 B3gntl1 B4galt5 B4galt6 C1galt1 C1galt1c1 Chst4 Galnt1 Galnt10 Galnt11 Galnt12 Galnt13 Galnt15 Galnt16 Galnt17 Galnt18 Galnt2 Galnt5 Galnt6 Galnt7 Galnt9 Galntl5 Galntl6 Gcnt1 Gcnt3 Gcnt4 Gcnt7 LOC102550196 Muc1 Muc13 Muc15 Muc19 Muc2 Muc20 Muc4 Muc5ac Muc5b Muc6 Qtgal Smc gcnt	Rattus norvegicus (Norway rat)
COPII-mediated vesicle transport	Alpha-1-antiproteinase Alpha-soluble NSF attachment protein Amphiregulin Ankyrin repeat domain 28 BET1 homolog Beta-soluble NSF attachment protein CD59 glycoprotein Casein kinase I isoform delta Cathepsin Z Coagulation factor VIII Collagen type VII alpha 1 chain Cornichon family AMPA receptor auxiliary protein 1 Dipeptidyl peptidase 1 Folate receptor alpha Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor 1 Golgi SNAP receptor complex member 2 Golgi reassembly-stacking protein 1 Golgin subfamily A member 2 Guanine nucleotide-exchange factor SEC12 Lectin, mannose-binding 2 Multiple coagulation factor deficiency protein 2 homolog Protein ERGIC-53-like Protein ERGIC-53 Protein SEC13 homolog Protein cornichon homolog 2 Protein cornichon homolog 3 Protein phosphatase 6, regulatory subunit 3 Protein transport protein SEC23 Protein transport protein Sec16B Protein transport protein Sec31A Protein transport protein sec16 Protransforming growth factor alpha Ras-related protein Rab-1A Ras-related protein Rab-1B SEC22 homolog C, vesicle trafficking protein SEC23 interacting protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Sec1 family domain-containing protein 1 Serine/threonine-protein phosphatase 6 catalytic subunit Small COPII coat GTPase SAR1B Synaptobrevin homolog YKT6 Syntaxin-17 Syntaxin-5 Trafficking from ER to golgi regulator Trafficking protein particle complex 2 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Vesicle-fusing ATPase Vesicle-trafficking protein SEC22a Vesicle-trafficking protein SEC22b	A0A0G2K112 A0A0G2K350 A0A0G2K626 A0A0G2K9K4 A0A8I5ZRE4 A0A8I5ZTA3 A0A8I6GHK6 B0BNE3 B2RYU6 B5DFC3 D0Q0Y7 D3ZE04 D3ZEB1 D3ZES2 D3ZW15 D3ZZA8 D4A3S0 E9PU02 F1MAH5 F1MAQ4 F7FPK8 G3V8M6 G3V8Q8 G3V9S9 M0R3S2 O35165 O35254 P01134 P10536 P17475 P19490 P24338 P27274 P41542 P54921 P80067 P85969 Q06486 Q08851 Q2KMM2 Q4KM74 Q5BJL8 Q5BJU5 Q5EGY4 Q5FB95 Q5HZY2 Q5U1Z2 Q5XFW8 Q62839 Q62896 Q62902 Q62991 Q63524 Q63584 Q642F4 Q64620 Q69BT7 Q6NYB7 Q75N33 Q8K5B3 Q9QUL6 Q9R1T3 Q9WTV0 Q9Z158 Q9Z2Q1	AABR07042915.1 Ankrd28 Areg Bet1 Cd59 Cnih1 Cnih2 Cnih3 Col7a1 Csnk1d Ctsc Ctsy Ctsz Erg1 Ergic53 Ergl F8 Folr1 GluA1 Glur1 Golga2 Gorasp1 Gosr2 Grasp65 Gria1 Gs27 Hckid LOC100909916 Lman1 Lman1l Lman2 Lztr2 Mcfd2 Napa Napb Napg Nsf Ppp6c Ppp6r3 Ppp6r3-ps1 Ppv Preb RGD1564492 Ra410 Rab1 Rab1A Rab1b Rgpr Rnp24 Saps3-ps1 Sar1b Sbdn Scfd1 Sdgf Sdnsf Sec12 Sec13 Sec13l1 Sec16a Sec16b Sec22a Sec22b Sec22c Sec22l1 Sec22l2 Sec23a Sec23ip Sec24a Sec24b Sec24c Sec24d Sec31a Sec31l1 Serpina1 Sly1 Snap Snapa Snapb Stx17 Stx5 Stx5a Stxbp1l2 Tfg Tgfa Tmed10 Tmed2 Tmp21 Trappc1 Trappc10 Trappc2 Trappc2l Trappc2ll1 Trappc3 Trappc4 Trappc5 Trappc6a Trappc6b Trappc9 Uso1 Vap1 Vdp Ykt6	Rattus norvegicus (Norway rat)
Cargo concentration in the ER	Alpha-1-antiproteinase Amphiregulin CD59 glycoprotein Cathepsin Z Coagulation factor VIII Collagen type VII alpha 1 chain Cornichon family AMPA receptor auxiliary protein 1 Dipeptidyl peptidase 1 Folate receptor alpha Glutamate receptor 1 Golgi SNAP receptor complex member 2 Guanine nucleotide-exchange factor SEC12 Lectin, mannose-binding 2 MIA SH3 domain ER export factor 2 MIA SH3 domain ER export factor 3 Multiple coagulation factor deficiency protein 2 homolog Protein ERGIC-53-like Protein ERGIC-53 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein SEC23 Protransforming growth factor alpha SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Small COPII coat GTPase SAR1B Syntaxin-5 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Vesicle-trafficking protein SEC22b	A0A0G2JVM2 A0A0G2K112 A0A0G2K626 A0A8I5ZSK4 B5DFC3 D0Q0Y7 D3ZE04 D3ZEB1 D3ZW15 D3ZZA8 F7FPK8 G3V8M6 G3V9S9 O35165 P01134 P17475 P19490 P24338 P27274 P80067 Q08851 Q4KM74 Q5BJU5 Q5FB95 Q5HZY2 Q62902 Q63524 Q63584 Q8K5B3 Q9R1T3 Q9WTV0	Areg Cd59 Cnih1 Cnih2 Cnih3 Col7a1 Ctsc Ctsy Ctsz Ergic53 Ergl F8 Folr1 GluA1 Glur1 Gosr2 Gria1 Gs27 Lman1 Lman1l Lman2 Mcfd2 Mia2 Mia3 Preb Rnp24 Sar1b Sdgf Sdnsf Sec12 Sec22b Sec22l1 Sec23a Sec24a Sec24b Sec24c Sec24d Serpina1 Stx5 Stx5a Tgfa Tmed10 Tmed2 Tmp21	Rattus norvegicus (Norway rat)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor	P10608 P15823 P18090 P19328 P22086 P22909 P23944 P26255 P43140	Adra1a Adra1b Adra1c Adra1d Adra2a Adra2b Adra2c Adrb1 Adrb1r Adrb2 Adrb2r Adrb3 Adrb3r	Rattus norvegicus (Norway rat)
Sialic acid metabolism	Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8E Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 1 Beta-galactoside alpha-2,6-sialyltransferase 2 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Carboxypeptidase Lactosylceramide alpha-2,3-sialyltransferase N-acetylneuraminate lyase N-acetylneuraminate synthase N-acylneuraminate cytidylyltransferase N-acylneuraminate-9-phosphatase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 Sialidase-1 Sialidase-2 Sialidase-3 Solute carrier family 35 member A1 Type 2 lactosamine alpha-2,3-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase exo-alpha-sialidase	A0A0G2JZH4 A0A1W2Q5Z7 A0A8I6AHG2 A0A8I6ARV9 A0A8I6GKW3 A1KQY6 D3ZUM4 D3ZWB7 G3V7T2 G3V8D0 G3V9C4 M0R3S4 O35826 P13721 P61131 P61943 P69060 Q02734 Q07977 Q11205 Q5M969 Q64627 Q64686 Q66H59 Q68G12 Q6ZXC8 Q6ZXY9 Q6ZYN8 Q701R3 Q99PW3 Q99PW5	Cmas Ctsa Glb1 Glcne Gne Hdhd4 Nanp Nans Neu1 Neu2 Neu3 Neu4 Npl Siat1 Siat10 Siat4b Siat4c Siat5 Siat6 Siat7c Siat8b Siat8e Siat9 Slc35a1 St3gal1 St3gal2 St3gal3 St3gal4 St3gal5 St3gal6 St6gal1 St6gal2 St6galnac1 St6galnac2 St6galnac3 St6galnac4 St6galnac5 St6galnac6 St8sia1 St8sia2 St8sia3 St8sia4 St8sia5 St8siav Stx siat7B	Rattus norvegicus (Norway rat)
NCAM1 interactions	Alpha-2,8-sialyltransferase 8B Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IV alpha 5 chain Neural cell adhesion molecule 1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	A0A0G2K742 A0A8I5ZZ86 A1KQY6 F1LRJ1 F1M6Q3 F1MA59 P13596 Q07977	Col4a1 Col4a2 Col4a3 Col4a4 Col4a5 LOC100911572 Ncam Ncam1 Siat8b St8sia2 St8sia4 Stx	Rattus norvegicus (Norway rat)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	P19328 P22086 P22909	Adra2a Adra2b Adra2c	Rattus norvegicus (Norway rat)
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase-1 Hyaluronidase-3 Iduronate 2-sulfatase Neurocan core protein Versican core protein (Fragments)	D3ZE16 F1LLW8 P47853 P50430 P55067 P55068 Q00657 Q01129 Q641X3 Q6AXR4 Q76HM9 Q76HN1 Q9ERB4 Q9ERQ6	Arsb Bcan Behab Bgn Caleb Cspg2 Cspg3 Cspg4 Cspg5 Dcn Hexa Hexb Hyal1 Hyal3 Ids Idua LOC100363795 Ncan Ng2 Ngc Vcan	Rattus norvegicus (Norway rat)	G27025MB
Termination of O-glycan biosynthesis	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Mucin 15, cell surface associated Mucin 19, oligomeric Mucin 20, cell surface associated Mucin 5AC, oligomeric mucus/gel-forming Mucin 5B, oligomeric mucus/gel-forming Mucin 6, oligomeric mucus/gel-forming Mucin-13 Mucin-1 Mucin-2 (Fragment) Mucin-4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase	A0A0G2JXL5 A0A0G2K8X5 A0A1W2Q5Z7 A0A8I6AAU0 A0A8I6AHG2 A0A8I6GM17 D3ZAU0 D4A6I9 F7EK02 P13721 P61131 P97881 Q02734 Q11205 Q62635 Q63661 Q64686 Q6ZYN8	AC096792.1 Muc1 Muc13 Muc15 Muc19 Muc2 Muc20 Muc4 Muc5ac Muc5b Muc6 Siat1 Siat4b Siat4c Siat5 Siat6 Siat7c Smc St3gal1 St3gal2 St3gal3 St3gal4 St6gal1 St6galnac2 St6galnac3 St6galnac4 siat7B	Rattus norvegicus (Norway rat)
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Alpha-actinin-1 Alpha-parvin Dual specificity testis-specific protein kinase 1 LIM and senescent cell antigen-like-containing domain protein Parvin, beta Paxillin Ras suppressor protein 1 Rho guanine nucleotide exchange factor 6	A0A8I5Y6N4 A0A8I6A6W3 D4A8F2 Q5XXR3 Q63572 Q66H76 Q9HB97 Q9Z1P2	Actn1 Actp Arhgef6 Lims1 Parva Parvb Pxn Rsu1 Tesk1	Rattus norvegicus (Norway rat)
Miscellaneous transport and binding events	Alpha-adducin Beta-adducin Cystinosin, lysosomal cystine transporter Dematin actin binding protein Gamma-adducin Leucine rich repeat containing 8 VRAC subunit B Lysosomal amino acid transporter 1 homolog Magnesium transporter MRS2 homolog, mitochondrial Magnesium transporter protein 1 Mineralization regulator ANKH NIPA magnesium transporter 1 NIPA magnesium transporter 2 NIPA-like domain containing 1 NIPA-like domain containing 2 NIPA-like domain containing 3 NIPA-like domain containing 4 Prolactin-inducible protein homolog Tumor suppressor candidate 3 Volume-regulated anion channel subunit LRRC8A Volume-regulated anion channel subunit LRRC8C Volume-regulated anion channel subunit LRRC8D Volume-regulated anion channel subunit LRRC8E Zinc-alpha-2-glycoprotein	A0A0G2K4T6 A0A8I5ZXT2 A0A8I6GMM8 B0BMY1 D3ZA72 D3ZG79 D3ZKE2 D3ZUV1 D4A758 F1M5J3 O35777 O70417 P58366 Q05764 Q3KRC6 Q498T9 Q4V8I7 Q5U308 Q62847 Q63028 Q63678 Q6AY49 Q9ET09	Add1 Add2 Add3 Ank Ankh Azgp1 Ctns Dmtn Iag2 Lrrc5 Lrrc8 Lrrc8a Lrrc8b Lrrc8c Lrrc8d Lrrc8e Magt1 Mrs2 Mrs2l Nipa1 Nipa2 Nipal1 Nipal2 Nipal3 Nipal4 Pip Pqlc2 Rpt Slc66a1 Tusc3	Rattus norvegicus (Norway rat)
Caspase-mediated cleavage of cytoskeletal proteins	Alpha-adducin Caspase 7 Caspase-3 Caspase-6 Caspase-8 Gelsolin Growth arrest-specific 2 Microtubule-associated protein tau Plectin Sorbin and SH3 domain-containing protein 2 Spectrin alpha chain, non-erythrocytic 1 Vimentin	A0A8I5ZQU7 G3V857 O35397 O35413 P16086 P19332 P30427 P31000 P55213 Q63028 Q68FP1 Q9JHX4	Add1 Argbp2 Casp3 Casp6 Casp7 Casp8 Cpp32 Gas2 Gsn Mapt Mch2 Mtapt Plec Plec1 Sorbs2 Spna2 Spta2 Sptan1 Tau Vim	Rattus norvegicus (Norway rat)
Choline catabolism	Alpha-aminoadipic semialdehyde dehydrogenase Betaine--homocysteine S-methyltransferase 1 Choline dehydrogenase, mitochondrial Choline transporter-like protein 1 Dimethylglycine dehydrogenase, mitochondrial Sarcosine dehydrogenase, mitochondrial	O09171 Q63342 Q64057 Q64380 Q6UPE0 Q8VII6	Ald7a1 Aldh7a1 Bhmt Cd92 Cdw92 Chdh Ctl1 Dmgdh Sardh Slc44a1	Rattus norvegicus (Norway rat)
Alpha-defensins	Alpha-defensin N-terminal domain-containing protein Anionic trypsin-2-like Anionic trypsin-2 Defensin alpha 10 Defensin alpha 11 Defensin alpha 24 Defensin alpha 4 Defensin alpha 6 Defensin alpha 8 Defensin alpha 9 Defensin alpha-like protein 1 NAD(P)(+)--arginine ADP-ribosyltransferase Neutrophil antibiotic peptide NP-2 Neutrophil antibiotic peptide NP-3B Serine protease 1 Similar to Anionic trypsin II precursor (Pretrypsinogen II) T-cell surface glycoprotein CD4 Trypsin 10 trypsin trypsin	A0A8I5Y5M6 A0A8I5ZME9 A0A8I6APH4 A0A8I6GLV0 D3ZJK0 D3ZQV0 F1LSU5 P00762 P00763 P05540 Q4JEI2 Q4JEI3 Q4JEI5 Q4JEI6 Q4JEI8 Q4JEI9 Q62714 Q62715 Q9Z1F1 W4VSR6	Art1 Cd4 Defa Defa-rs1 Defa10 Defa11 Defa24 Defa6 Defa8 Defa9 Defal1 Defcr4 ENSRNOG00000064390 LOC100365995 LOC102554637 LOC683849 Np4 Prss1 Prss2 Prss2l1 Prss3 Rd5 Trp1 Try1 Try10 Try2 Try4 Try5 Tryp1	Rattus norvegicus (Norway rat)
Defensins	Alpha-defensin N-terminal domain-containing protein Beta-defensin 14 Beta-defensin 17 Beta-defensin 18 Beta-defensin 1 Beta-defensin 25 Beta-defensin 30 Beta-defensin 41 Beta-defensin 43 Beta-defensin 4 Beta-defensin Beta-defensin Beta-defensin Beta-defensin Defensin alpha 10 Defensin alpha 11 Defensin alpha 24 Defensin alpha 4 Defensin alpha 6 Defensin alpha 8 Defensin alpha 9 Defensin alpha-like protein 1 Neutrophil antibiotic peptide NP-2 Neutrophil antibiotic peptide NP-3B	A0A8I6GLV0 A0A8J8YAJ6 F1LSU5 F7EMF7 F7FD31 O88514 O89117 Q32ZF3 Q32ZF5 Q32ZG2 Q32ZG7 Q32ZH1 Q32ZH4 Q32ZH5 Q32ZH7 Q4JEI2 Q4JEI3 Q4JEI5 Q4JEI6 Q4JEI8 Q4JEI9 Q62714 Q62715 Q9Z1F1	Defa Defa-rs1 Defa10 Defa11 Defa24 Defa6 Defa8 Defa9 Defal1 Defb1 Defb14 Defb17 Defb18 Defb2 Defb21 Defb24 Defb25 Defb28 Defb3 Defb30 Defb36 Defb4 Defb41 Defb43 Defcr4 ENSRNOG00000064390 Np4 Rd5	Rattus norvegicus (Norway rat)
ALPK1 signaling pathway	Alpha-kinase 1 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 TRAF-interacting protein with FHA domain-containing protein A Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 D3ZTA7 P0C8E4 P0CG51 P62982 Q5U303 Q5XIB9 Q63429	Alpk1 LOC100360645 Map3k7 Map3k7ip2 Rps27a Tab1 Tab2 Tab3 Tifa Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Cell-extracellular matrix interactions	Alpha-parvin FERM domain containing kindlin 2 Filamin A Filamin binding LIM protein 1 Filamin-C Integrin-linked protein kinase LIM and senescent cell antigen-like-containing domain protein LIM and senescent cell antigen-like-containing domain protein Parvin, beta Vasodilator-stimulated phosphoprotein	A0A0G2KAE1 A0A8I5Y6N4 A0A8I5ZV49 A0A8I6A6W3 A0A8I6G699 D3ZHA0 F7EWC1 F7FP13 Q99J82 Q9HB97	Abpl Actp Fblim1 Fermt2 Fln2 Flna Flnc ILK1 ILK2 Ilk Lims1 Lims2 Parva Parvb Vasp	Rattus norvegicus (Norway rat)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	Alpha-parvin Integrin beta-1 Integrin-linked protein kinase Paxillin	P49134 Q66H76 Q99J82 Q9HB97	Actp ILK1 ILK2 Ilk Itgb1 Parva Pxn	Rattus norvegicus (Norway rat)
PKR-mediated signaling	Alpha-synuclein Cellular tumor antigen p53 Cyclin-dependent kinase 1 Cytoplasmic protein DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase FA complementation group A FA complementation group B FA complementation group E FA complementation group F FA complementation group G FA complementation group L FA complementation group M FA core complex associated protein 100 FA core complex associated protein 24 Fanconi anemia core complex-associated protein 20 Fanconi anemia group C protein homolog Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 ISG15 ubiquitin-like modifier Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Microtubule-associated protein tau Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleophosmin Protein phosphatase 2 scaffold subunit A alpha RBR-type E3 ubiquitin transferase RISC-loading complex subunit TARBP2 RNA helicase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Sphingosine kinase 1 Tripartite motif-containing 25 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin/ISG15-conjugating enzyme E2 L6 mitogen-activated protein kinase kinase	A0A0G2JWL4 A0A0G2JX93 A0A0G2K7F0 A0A8I5ZNL4 A0A8I6ABZ7 A0A8I6AGX8 A0A8I6AH74 A0A8I6ANR6 B2RZ33 D3ZAU3 D3ZDI7 D3ZE71 D3ZXL1 D4A3X3 D4A5I2 D4A9N5 D4AAA5 F1M0R6 F1M286 O35870 P0DMW0 P0DMW1 P10361 P13084 P14659 P19332 P35233 P37377 P39951 P52631 P55063 P55266 P62716 P63018 P63331 Q3SWU0 Q4QQT4 Q4V8C7 Q4V8J2 Q5XI34 Q63184 Q66HG9 Q6TMG5 Q7TP98 Q91V26 Q925D6 Q9JIL3 Q9QY78 Q9R0T3	Adar Arih1 Cdc2 Cdc2a Cdk1 Cdkn1 Chuk Dhx9 Dnajc3 Dsrad Eif2ak2 Faap100 Faap20 Faap24 Facc Fanca Fancb Fancc Fance Fancf Fancg Fancl Fancm Hsc70 Hsc73 Hsp70-1 Hsp70-2 Hsp70-3 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hst70 Ikbkb Ikbkg Ikkb Ilf2 Ilf3 Ips1 Isg15 Map2k6 Mapt Mavs Mkk6 Mtapt Nck1 Nemo Npm1 P53 P58ipk Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Prkr Prkra Ptpn2 RGD1564719 Snca Sphk1 Stat1 Stat3 Stat4 Tarbp2 Tau Tp53 Trim25 Ube2l6 Visa	Rattus norvegicus (Norway rat)

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